2D39

trivalent recognition unit of innate immunity system; crystal structure of human m-ficolin fibrinogen-like domain

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 74
  • Norm. En. per Res.: -2.9533
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-39.986	-43.2879	-128.861	-212.1349	75	4	2	5309	4	9	14
A-C	-42.5094	-44.8215	-131.211	-218.5419	74	10	2	5487	4	13	15
B-C	-36.408	4.6683	-127.428	-159.1676	70	8	2	5253	4	9	13

Interface residues

• A-B: ALA174A, ARG124B, ARG140A, ARG160B, ARG170A, ASN190A, ASN192A, ASN214B, ASP123B, ASP147B, ASP149B, ASP151B, ASP163A, ASP167A, ASP210B, CYS146B, GLN177A, GLN182A, GLN182B, GLU185A, GLU212B, GLU320B, GLY125B, GLY130B, GLY152B, GLY164A, GLY178A, GLY180A, GLY184A, GLY184B, GLY189A, GLY213B, HIS132B, HIS215B, ILE193A, LEU122B, LEU128B, LEU136A, LEU142A, LEU145A, LEU145B, LEU183A, LEU183B, LEU188A, LYS176A, LYS317B, MET148B, MET162A, MET162B, MET294A, PHE127B, PHE158A, PHE179A, PHE186A, PHE186B, PHE211B, PRO141A, SER129B, SER165A, SER181A, SER181B, THR133A, THR143A, THR150B, TRP131A, TRP131B, TRP187A, TYR126B, TYR175A, VAL144A, VAL157A, VAL157B, VAL166A, VAL209B, VAL318B
• A-C: ALA174C, ARG124A, ARG140C, ARG160A, ARG170C, ASN190C, ASN192C, ASN214A, ASP147A, ASP149A, ASP151A, ASP163C, ASP167C, ASP210A, CYS146A, GLN177C, GLN182A, GLN182C, GLU185C, GLU212A, GLU320A, GLY125A, GLY130A, GLY152A, GLY164C, GLY178C, GLY180C, GLY184A, GLY184C, GLY189C, GLY213A, HIS132A, HIS215A, ILE193C, LEU122A, LEU128A, LEU136C, LEU142C, LEU145A, LEU145C, LEU183A, LEU183C, LEU188C, LYS176C, LYS317A, MET148A, MET162A, MET162C, MET294C, PHE127A, PHE158C, PHE179C, PHE186A, PHE186C, PHE211A, PRO141C, SER129A, SER165C, SER181A, SER181C, THR133C, THR143C, THR150A, TRP131A, TRP131C, TRP187C, TYR126A, TYR175C, VAL144C, VAL157A, VAL157C, VAL166C, VAL209A, VAL318A
• B-C: ALA174B, ARG124C, ARG140B, ARG160C, ARG170B, ASN190B, ASN192B, ASP123C, ASP147C, ASP149C, ASP151C, ASP163B, ASP167B, CYS146C, GLN177B, GLN182B, GLN182C, GLU185B, GLU320C, GLY125C, GLY130C, GLY152C, GLY164B, GLY178B, GLY180B, GLY184B, GLY184C, GLY189B, GLY213C, HIS132C, HIS215C, ILE193B, LEU122C, LEU128C, LEU136B, LEU142B, LEU145B, LEU145C, LEU183B, LEU183C, LEU188B, LYS176B, LYS317C, MET148C, MET162B, MET162C, PHE127C, PHE158B, PHE179B, PHE186B, PHE186C, PRO141B, SER129C, SER165B, SER181B, SER181C, THR133B, THR143B, THR150C, TRP131B, TRP131C, TRP187B, TYR126C, TYR175B, VAL144B, VAL157B, VAL157C, VAL166B, VAL209C, VAL318C