2D10

crystal structure of the radixin ferm domain complexed with the nherf-1 c-terminal tail peptide

• Total interactions analyzed: 28
• Total true interactions: 10
• Strongest Interaction:
  • Chains: A-E
  • Int. Res.: 71
  • Norm. En. per Res.: -3.5424
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-20.6117	-39.1543	-34.3125	-94.0785	64	1	0	2215	4	43	44
A-C	-7.243	2.4161	-20.2217	-25.0487	19	1	0	1030	3	21	17
A-D	-40.6323	3.8818	-295.719	-332.4696	133	20	6	12477	0	47	55
A-E	-11.2909	1.309	-241.53	-251.5119	71	4	5	9283	0	25	15
B-C	-33.3625	2.4166	-294.398	-325.3439	138	26	5	12786	0	46	55
B-D	0.0	0.0	-10.4238	-10.4238	15	1	0	585	0	8	10
B-F	-8.6437	5.284	-220.049	-223.4087	73	3	5	8786	1	26	14
C-E	0.0	0.0	-6.8532	-6.8532	5	0	0	197	0	0	0
C-G	-9.146	0.9799	-216.195	-224.3611	76	5	5	8762	0	22	15
D-H	-30.4207	-3.8913	-230.555	-264.8671	77	4	4	8807	1	25	15

Interface residues

• A-B: ALA148A, ARG151A, ARG156A, ARG246B, ARG273A, ARG275A, ARG293B, ARG8A, ASN149A, ASN23B, ASN251B, ASN62B, ASN74A, ASP113A, ASP150A, ASP231A, ASP232A, ASP252B, ASP261B, ASP31B, ASP69B, GLN155A, GLN160A, GLN28B, GLN67B, GLN68B, GLN77A, GLU159A, GLU207A, GLU215A, GLU229A, GLU73A, GLY54A, HIS161A, HIS230A, HIS288B, ILE260B, LEU158A, LEU234A, LEU274B, LEU281B, LEU61B, LYS165A, LYS233A, LYS262B, LYS278B, LYS27B, LYS296B, LYS53A, LYS60B, LYS63B, LYS64B, LYS71A, MET292B, PHE250B, PRO297B, PRO75A, SER52A, THR24B, THR25B, THR299B, TRP217A, TYR55A, VAL157A
• A-C: ARG180C, ASN138C, ASN210A, ASP231A, ASP232A, GLU140C, GLU177C, GLU215A, GLU229A, GLY213A, HIS230A, ILE141C, LEU216A, LYS139C, LYS143C, LYS211A, LYS212A, THR214A, TYR137C
• A-D: ALA132A, ALA132D, ALA148A, ALA148D, ALA14A, ALA14D, ALA19A, ALA19D, ARG100A, ARG100D, ARG151A, ARG151D, ARG180A, ARG180D, ARG184A, ARG184D, ARG8A, ARG8D, ASN138A, ASN138D, ASN149A, ASN149D, ASN23A, ASN23D, ASN6A, ASN6D, ASN74A, ASN74D, ASP136A, ASP136D, ASP13A, ASP13D, ASP150A, ASP150D, ASP31A, ASP31D, GLN131A, GLN131D, GLN21A, GLN21D, GLN28A, GLN28D, GLN32A, GLN32D, GLU140A, GLU140D, GLU15A, GLU15D, GLU166A, GLU166D, GLU169A, GLU169D, GLU17A, GLU17D, GLU96D, GLY135A, GLY135D, GLY145A, GLY145D, GLY181D, GLY38A, GLY38D, HIS142A, HIS142D, HIS176A, HIS176D, ILE141A, ILE141D, ILE20A, ILE20D, ILE5A, ILE5D, ILE97A, ILE97D, LEU147A, LEU147D, LEU16A, LEU16D, LEU29A, LEU29D, LEU39D, LEU76A, LEU76D, LYS133A, LYS133D, LYS139A, LYS139D, LYS143A, LYS143D, LYS165A, LYS165D, LYS27A, LYS27D, LYS35A, LYS35D, LYS3A, LYS3D, LYS64D, PHE18A, PHE18D, PHE30A, PHE30D, PRO144A, PRO144D, PRO22D, PRO4A, PRO4D, PRO75A, PRO75D, THR24A, THR24D, THR25A, THR25D, THR36A, THR36D, TYR134A, TYR134D, TYR137A, TYR137D, TYR146A, TYR146D, VAL130A, VAL130D, VAL33A, VAL33D, VAL34A, VAL34D, VAL37A, VAL37D, VAL7A, VAL7D, VAL9A, VAL9D
• A-E: ALA264A, ALA343E, ARG246A, ARG342E, ASN210A, ASN226A, ASN247A, ASN352E, ASN357E, ASP197A, ASP261A, ASP266A, ASP347E, GLN196A, GLN345E, GLU199A, GLU215A, GLU229A, GLU244A, GLU353E, GLY213A, GLY239A, HIS230A, ILE208A, ILE227A, ILE238A, ILE245A, ILE248A, ILE257A, ILE260A, LEU198A, LEU216A, LEU218A, LEU223A, LEU225A, LEU234A, LEU354E, LEU358E, LYS209A, LYS211A, LYS212A, LYS237A, LYS258A, LYS263A, LYS341E, LYS350E, LYS351E, MET200A, MET346E, PHE240A, PHE267A, PHE269A, PHE355E, PRO236A, PRO241A, PRO259A, PRO265A, PRO344E, SER243A, SER340E, SER349E, SER356E, THR214A, THR235A, TRP217A, TRP242A, TRP348E, TYR228A, TYR270A, VAL256A, VAL268A
• B-C: ALA132B, ALA132C, ALA148B, ALA148C, ALA14B, ALA14C, ALA19B, ALA19C, ARG100B, ARG100C, ARG151B, ARG151C, ARG180C, ARG184B, ARG184C, ARG40B, ARG40C, ARG8B, ARG8C, ASN138B, ASN138C, ASN149B, ASN149C, ASN23B, ASN23C, ASN6B, ASN6C, ASN74B, ASN74C, ASP136B, ASP136C, ASP13B, ASP13C, ASP150B, ASP150C, ASP31B, ASP31C, GLN131B, GLN131C, GLN21B, GLN21C, GLN28B, GLN28C, GLN32B, GLN32C, GLU140B, GLU140C, GLU15B, GLU15C, GLU166B, GLU166C, GLU169B, GLU169C, GLU17B, GLU17C, GLY135B, GLY135C, GLY145B, GLY145C, GLY181C, GLY38B, GLY38C, HIS142B, HIS142C, HIS176B, HIS176C, ILE141B, ILE141C, ILE20B, ILE20C, ILE5B, ILE5C, ILE97B, ILE97C, LEU147B, LEU147C, LEU16B, LEU16C, LEU183B, LEU183C, LEU29B, LEU29C, LEU39B, LEU39C, LEU76B, LEU76C, LYS133B, LYS133C, LYS139B, LYS139C, LYS143B, LYS143C, LYS165B, LYS165C, LYS27B, LYS27C, LYS35B, LYS35C, LYS3B, LYS3C, LYS64B, LYS64C, MET182C, PHE18B, PHE18C, PHE30B, PHE30C, PRO144B, PRO144C, PRO22B, PRO22C, PRO4B, PRO4C, PRO75B, PRO75C, THR24B, THR24C, THR25B, THR25C, THR36B, THR36C, TYR134B, TYR134C, TYR137B, TYR137C, TYR146B, TYR146C, VAL130B, VAL130C, VAL33B, VAL33C, VAL34B, VAL37B, VAL37C, VAL7B, VAL7C, VAL9B, VAL9C
• B-D: ASN251B, ASN6D, ASN74D, ASP252B, GLU17D, GLU73D, LYS253B, LYS254B, LYS3D, PHE255B, PRO4D, PRO75D, TYR270B, VAL256B, VAL268B
• B-F: ALA264B, ALA343F, ARG246B, ARG342F, ASN210B, ASN226B, ASN247B, ASN352F, ASN357F, ASP197B, ASP221B, ASP261B, ASP266B, ASP347F, GLN196B, GLN345F, GLU199B, GLU215B, GLU229B, GLU244B, GLU353F, GLY213B, GLY239B, HIS230B, ILE208B, ILE227B, ILE238B, ILE245B, ILE248B, ILE257B, ILE260B, LEU198B, LEU216B, LEU218B, LEU223B, LEU225B, LEU234B, LEU354F, LEU358F, LYS209B, LYS211B, LYS212B, LYS237B, LYS258B, LYS263B, LYS341F, LYS350F, LYS351F, MET346F, PHE240B, PHE267B, PHE269B, PHE355F, PRO236B, PRO241B, PRO259B, PRO265B, PRO344F, SER243B, SER339F, SER340F, SER349F, SER356F, THR214B, THR235B, TRP217B, TRP242B, TRP348F, TYR228B, TYR270B, VAL203B, VAL256B, VAL268B
• C-E: ASN357E, GLU140C, LEU358E, LYS139C, TYR137C
• C-G: ALA264C, ALA343G, ARG246C, ARG342G, ASN210C, ASN226C, ASN247C, ASN352G, ASN357G, ASP197C, ASP261C, ASP266C, ASP347G, ASP88C, GLN196C, GLN345G, GLU199C, GLU215C, GLU229C, GLU244C, GLU353G, GLU87C, GLY213C, GLY239C, HIS230C, ILE208C, ILE227C, ILE238C, ILE245C, ILE248C, ILE257C, ILE260C, LEU198C, LEU216C, LEU218C, LEU223C, LEU225C, LEU234C, LEU354G, LEU358G, LYS209C, LYS211C, LYS212C, LYS237C, LYS258C, LYS262C, LYS263C, LYS341G, LYS350G, LYS351G, MET200C, MET346G, PHE240C, PHE267C, PHE269C, PHE355G, PRO236C, PRO241C, PRO259C, PRO265C, PRO344G, SER243C, SER339G, SER340G, SER349G, SER356G, THR214C, THR235C, TRP217C, TRP242C, TRP348G, TYR201C, TYR228C, TYR270C, VAL256C, VAL268C
• D-H: ALA264D, ALA343H, ARG246D, ARG342H, ASN210D, ASN226D, ASN247D, ASN352H, ASN357H, ASP197D, ASP221D, ASP261D, ASP266D, ASP347H, GLN196D, GLN345H, GLU199D, GLU215D, GLU229D, GLU244D, GLU353H, GLY213D, GLY239D, HIS230D, ILE194D, ILE208D, ILE227D, ILE238D, ILE245D, ILE248D, ILE257D, ILE260D, LEU198D, LEU216D, LEU218D, LEU223D, LEU225D, LEU234D, LEU354H, LEU358H, LYS193D, LYS209D, LYS211D, LYS212D, LYS237D, LYS258D, LYS262D, LYS263D, LYS341H, LYS350H, LYS351H, MET200D, MET346H, PHE240D, PHE267D, PHE269D, PHE355H, PRO236D, PRO241D, PRO259D, PRO265D, PRO344H, SER243D, SER339H, SER340H, SER349H, SER356H, THR214D, THR235D, TRP217D, TRP242D, TRP348H, TYR201D, TYR228D, TYR270D, VAL256D, VAL268D