2CZC

crystal structure of glyceraldehyde-3-phosphate dehydrogenase from pyrococcus horikoshii ot3

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 131
  • Norm. En. per Res.: -4.5702
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-82.5992	-71.8276	-387.736	-542.1628	133	15	4	14093	16	91	93
A-C	0.0	8.2101	-125.323	-117.1129	46	4	5	5495	0	6	8
A-D	-67.6389	-17.1601	-567.654	-652.453	159	32	24	23373	7	32	26
B-C	-59.6826	-21.6335	-590.945	-672.2611	160	29	23	23549	6	33	26
B-D	0.0	3.2876	-117.712	-114.4244	46	5	5	5376	0	6	8
C-D	-117.4829	-94.8282	-386.384	-598.6951	131	14	4	13928	16	88	92

Interface residues

• A-B: ALA20A, ALA20B, ALA257A, ALA257B, ALA263A, ALA263B, ALA41A, ALA41B, ALA44A, ALA44B, ARG16A, ARG16B, ARG264A, ARG264B, ARG268A, ARG268B, ARG43A, ARG43B, ASN172A, ASN172B, ASN180A, ASN180B, ASN271A, ASN271B, ASN272A, ASN272B, ASP170A, ASP170B, ASP173A, ASP173B, ASP254A, ASP254B, ASP265A, ASP265B, ASP38A, ASP38B, GLN258A, GLN258B, GLN298A, GLN298B, GLU248A, GLU248B, GLU250A, GLU250B, GLU261A, GLU261B, GLU269A, GLU269B, GLU299A, GLU299B, GLU40A, GLU40B, GLU46A, GLU46B, GLU65A, GLU65B, GLY252A, GLY252B, HIS267A, HIS267B, HIS297A, HIS297B, ILE179A, ILE179B, ILE259A, ILE259B, ILE260A, ILE260B, LEU215A, LEU215B, LEU266A, LEU266B, LEU273A, LEU273B, LEU333A, LEU333B, LEU47A, LEU47B, LYS15A, LYS15B, LYS175A, LYS175B, LYS23A, LYS23B, LYS249A, LYS249B, LYS251A, LYS251B, LYS34A, LYS34B, LYS36A, LYS36B, LYS64A, LYS64B, PHE247A, PHE247B, PHE253A, PHE253B, PHE262A, PHE262B, PHE39A, PHE39B, PHE67A, PHE67B, PRO171A, PRO171B, PRO212A, PRO212B, PRO37A, PRO37B, SER255A, SER255B, SER300A, SER300B, THR12A, THR12B, THR174A, THR174B, THR213B, THR214A, THR214B, THR22A, THR22B, THR256A, THR256B, TRP270A, TRP270B, TYR10A, TYR10B, TYR19A, TYR19B, TYR42A, TYR42B
• A-C: ALA168A, ALA168C, ALA169A, ALA169C, ALA181A, ALA181C, ARG167A, ARG167C, ARG176A, ARG176C, ASN172A, ASN172C, ASN180A, ASN180C, ASP170A, ASP170C, ASP173A, ASP173C, GLY177A, GLY177C, ILE179A, ILE179C, ILE182A, ILE182C, LEU215A, LEU215C, LYS175A, LYS175C, LYS183A, LYS183C, PRO171A, PRO171C, PRO178A, PRO178C, PRO212A, PRO212C, THR174A, THR174C, THR213A, THR213C, THR214A, THR214C, VAL210A, VAL210C, VAL211A, VAL211C
• A-D: ALA162A, ALA162D, ALA168A, ALA168D, ALA169A, ALA169D, ALA181A, ALA181D, ALA208A, ALA208D, ALA257A, ALA257D, ALA295A, ALA295D, ARG166A, ARG166D, ARG167A, ARG167D, ARG289A, ARG289D, ASN180A, ASN180D, ASN203A, ASN203D, ASN284A, ASN284D, ASN288A, ASN288D, ASP158A, ASP158D, ASP254A, ASP254D, GLN258A, GLN258D, GLN294A, GLN294D, GLU187A, GLU187D, GLU205A, GLU205D, GLU224A, GLU224D, GLU248A, GLU248D, GLU250A, GLU250D, GLU281A, GLU281D, GLY287A, GLY287D, HIS217A, HIS217D, HIS219A, HIS219D, ILE165A, ILE165D, ILE179A, ILE179D, ILE182A, ILE182D, ILE204A, ILE204D, ILE259A, ILE259D, ILE260A, ILE260D, ILE283A, ILE283D, ILE285A, ILE285D, ILE293A, ILE293D, LEU215A, LEU215D, LEU290A, LEU290D, LYS183A, LYS183D, LYS231A, LYS249A, LYS249D, LYS280A, LYS280D, LYS286A, LYS286D, MET164A, MET164D, MET207A, MET207D, MET216A, MET216D, MET222A, MET222D, PHE209A, PHE209D, PHE247A, PHE247D, PHE253A, PHE253D, PHE291A, PHE291D, PRO171A, PRO171D, PRO178A, PRO178D, PRO184A, PRO184D, PRO189A, PRO189D, PRO194A, PRO194D, PRO212A, PRO212D, SER190A, SER190D, SER220A, SER220D, SER255A, SER255D, SER282A, SER282D, THR185A, THR185D, THR206A, THR206D, THR213A, THR213D, THR214A, THR214D, THR256A, THR256D, TRP279A, TRP279D, TYR159A, TYR159D, TYR161A, TYR161D, TYR292A, TYR292D, VAL160A, VAL160D, VAL163A, VAL163D, VAL186A, VAL186D, VAL188A, VAL188D, VAL210A, VAL210D, VAL211A, VAL211D, VAL218A, VAL218D, VAL221A, VAL221D, VAL223D, VAL278A, VAL296A, VAL296D
• B-C: ALA162B, ALA162C, ALA168B, ALA168C, ALA169B, ALA169C, ALA181B, ALA181C, ALA208B, ALA208C, ALA257B, ALA257C, ALA295B, ALA295C, ARG166B, ARG166C, ARG167B, ARG167C, ARG289B, ARG289C, ASN180B, ASN180C, ASN203B, ASN203C, ASN284B, ASN284C, ASN288B, ASN288C, ASP158B, ASP158C, ASP254B, ASP254C, GLN197B, GLN258B, GLN258C, GLN294B, GLN294C, GLU187B, GLU187C, GLU205B, GLU205C, GLU224B, GLU224C, GLU248B, GLU248C, GLU250B, GLU250C, GLU281B, GLU281C, GLY193B, GLY287B, GLY287C, HIS217B, HIS217C, HIS219B, HIS219C, ILE165B, ILE165C, ILE179B, ILE179C, ILE182B, ILE182C, ILE204B, ILE204C, ILE259B, ILE259C, ILE260B, ILE260C, ILE283B, ILE283C, ILE285B, ILE285C, ILE293B, ILE293C, LEU215B, LEU215C, LEU290B, LEU290C, LYS183B, LYS183C, LYS231B, LYS231C, LYS249B, LYS249C, LYS280B, LYS280C, LYS286B, LYS286C, MET164B, MET164C, MET207B, MET207C, MET216B, MET216C, MET222B, MET222C, PHE209B, PHE209C, PHE247B, PHE247C, PHE253B, PHE253C, PHE291B, PHE291C, PRO171B, PRO171C, PRO178B, PRO178C, PRO184B, PRO184C, PRO189B, PRO189C, PRO194B, PRO194C, PRO212B, PRO212C, SER190B, SER190C, SER220B, SER220C, SER255B, SER255C, SER282B, SER282C, THR185B, THR185C, THR206B, THR206C, THR213B, THR213C, THR214B, THR214C, THR256B, THR256C, TRP279B, TRP279C, TYR159B, TYR159C, TYR161B, TYR161C, TYR292B, TYR292C, VAL160B, VAL160C, VAL163B, VAL163C, VAL186B, VAL186C, VAL188B, VAL188C, VAL210B, VAL210C, VAL211B, VAL211C, VAL218B, VAL218C, VAL221B, VAL221C, VAL296B, VAL296C
• B-D: ALA168B, ALA168D, ALA169B, ALA169D, ALA181B, ALA181D, ARG167B, ARG167D, ARG176B, ARG176D, ASN172B, ASN172D, ASN180B, ASN180D, ASP170B, ASP170D, ASP173B, ASP173D, GLY177B, GLY177D, ILE179B, ILE179D, ILE182B, ILE182D, LEU215B, LEU215D, LYS175B, LYS175D, LYS183B, LYS183D, PRO171B, PRO171D, PRO178B, PRO178D, PRO212B, PRO212D, THR174B, THR174D, THR213B, THR213D, THR214B, THR214D, VAL210B, VAL210D, VAL211B, VAL211D
• C-D: ALA20D, ALA257C, ALA257D, ALA263C, ALA263D, ALA41C, ALA41D, ALA44C, ALA44D, ARG16C, ARG16D, ARG264C, ARG264D, ARG268C, ARG268D, ARG43C, ARG43D, ASN172C, ASN172D, ASN180C, ASN180D, ASN271C, ASN271D, ASN272C, ASN272D, ASP170C, ASP170D, ASP173C, ASP173D, ASP254C, ASP254D, ASP265C, ASP265D, ASP38C, ASP38D, GLN258C, GLN258D, GLN298C, GLN298D, GLU248C, GLU248D, GLU250C, GLU250D, GLU261C, GLU261D, GLU269C, GLU269D, GLU299C, GLU299D, GLU40C, GLU40D, GLU46C, GLU46D, GLU65C, GLU65D, GLY252C, GLY252D, GLY66D, HIS267C, HIS267D, HIS297C, HIS297D, ILE179C, ILE179D, ILE259C, ILE259D, ILE260C, ILE260D, LEU215C, LEU215D, LEU266C, LEU266D, LEU273C, LEU273D, LEU333C, LEU333D, LEU47C, LEU47D, LYS15C, LYS15D, LYS175C, LYS175D, LYS23C, LYS23D, LYS249C, LYS249D, LYS251C, LYS251D, LYS34C, LYS36C, LYS36D, PHE247C, PHE247D, PHE253C, PHE253D, PHE262C, PHE262D, PHE39C, PHE39D, PHE67C, PHE67D, PRO171C, PRO171D, PRO212C, PRO212D, PRO37C, PRO37D, SER255C, SER255D, SER300C, SER300D, THR12C, THR12D, THR174C, THR174D, THR213C, THR214C, THR214D, THR22C, THR22D, THR256C, THR256D, TRP270C, TRP270D, TYR10C, TYR10D, TYR19C, TYR19D, TYR274D, TYR42C, TYR42D