2CX9

crystal structure of acyl-coa dehydrogenase

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 167
  • Norm. En. per Res.: -4.0494
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-106.4556	-95.7694	-530.206	-732.431	182	17	6	19474	13	83	88
A-C	-73.5955	-84.9662	-458.042	-616.6037	169	32	31	20813	12	73	55
A-D	-24.3577	7.2598	-40.941	-58.0389	22	4	0	1270	0	10	10
B-C	-27.044	7.3262	-42.473	-62.1908	20	3	0	1342	0	10	10
B-D	-95.6009	-116.2735	-464.373	-676.2475	167	19	31	20988	11	73	56
C-D	-129.2312	-83.1846	-535.835	-748.2507	186	13	6	19451	11	79	83

Interface residues

• A-B: ALA136A, ALA136B, ALA137A, ALA137B, ALA138A, ALA138B, ALA276A, ALA276B, ALA340A, ALA340B, ALA362A, ALA362B, ALA84B, ARG203A, ARG274A, ARG274B, ARG279A, ARG279B, ARG357A, ARG357B, ARG35A, ARG35B, ARG360A, ARG360B, ARG363A, ARG363B, ARG366A, ARG366B, ARG381A, ARG381B, ASP135A, ASP135B, ASP338A, ASP338B, ASP34A, ASP352A, ASP352B, ASP361A, ASP361B, CYS337A, CYS337B, GLN157A, GLN157B, GLN217A, GLN217B, GLN342A, GLN342B, GLU129A, GLU129B, GLU181A, GLU181B, GLU205A, GLU205B, GLU206A, GLU206B, GLU275A, GLU275B, GLU285A, GLU285B, GLU331A, GLU331B, GLU339A, GLU339B, GLU356A, GLU356B, GLU373A, GLU373B, GLY131A, GLY131B, GLY133A, GLY133B, GLY209A, GLY209B, GLY278A, GLY278B, GLY286A, GLY286B, GLY345A, GLY345B, GLY346A, GLY346B, GLY348A, GLY348B, GLY368A, GLY368B, GLY370A, GLY370B, GLY83B, ILE281A, ILE281B, ILE341A, ILE341B, ILE343A, ILE343B, ILE367A, ILE367B, ILE374A, ILE374B, LEU208A, LEU208B, LEU210A, LEU210B, LEU259B, LEU327A, LEU327B, LEU344A, LEU344B, LEU364A, LEU364B, LEU375A, LEU375B, LEU377A, LEU377B, LEU87A, LEU87B, LYS183A, LYS183B, LYS207A, LYS207B, LYS290A, LYS290B, LYS326A, LYS326B, LYS335A, LYS335B, LYS351A, LYS351B, LYS376A, LYS376B, MET255A, MET255B, PHE158A, PHE158B, PHE238A, PHE238B, PHE277A, PHE277B, PHE284A, PHE284B, PRO130A, PRO130B, PRO180A, PRO180B, SER132A, SER132B, SER134A, SER134B, SER213A, SER213B, SER330A, SER330B, SER372A, SER372B, THR128A, THR128B, THR211A, THR211B, THR215A, THR215B, THR365A, THR365B, THR371A, THR371B, TRP359A, TRP359B, TYR270A, TYR270B, TYR347A, TYR347B, TYR349A, TYR349B, TYR353A, TYR353B, TYR358B, VAL287A, VAL287B, VAL334A, VAL334B, VAL350A, VAL350B, VAL355A, VAL355B
• A-C: ALA267A, ALA267C, ALA269A, ALA269C, ALA271A, ALA271C, ALA282A, ALA282C, ALA292A, ALA292C, ALA294A, ALA294C, ALA295A, ALA295C, ALA300A, ALA300C, ALA301A, ALA301C, ALA308A, ALA308C, ALA309A, ALA309C, ALA314A, ALA314C, ALA323A, ALA323C, ALA325A, ALA325C, ALA329A, ALA329C, ALA332A, ALA332C, ALA380A, ALA380C, ALA386A, ALA386C, ARG12A, ARG12C, ARG279C, ARG302A, ARG302C, ARG316A, ARG316C, ARG381A, ARG381C, ARG382A, ARG382C, ARG69A, ARG69C, ASP265A, ASP265C, ASP313A, GLN261A, GLN261C, GLN324A, GLN324C, GLU283A, GLU283C, GLU285A, GLU285C, GLU293A, GLU293C, GLU297A, GLU297C, GLU299A, GLU299C, GLU310A, GLU310C, GLU321A, GLU321C, GLU331A, GLU331C, GLU373A, GLU373C, GLU385A, GLU385C, GLU6A, GLU6C, GLU7A, GLY273A, GLY273C, GLY286A, GLY286C, GLY315A, ILE281A, ILE281C, ILE343A, ILE374A, ILE374C, ILE379A, ILE379C, LEU264A, LEU264C, LEU268A, LEU268C, LEU291A, LEU291C, LEU298A, LEU298C, LEU303A, LEU303C, LEU304A, LEU304C, LEU306A, LEU306C, LEU311A, LEU311C, LEU320A, LEU320C, LEU327A, LEU327C, LEU375A, LEU375C, LEU377A, LEU377C, LEU383A, LEU383C, LEU384A, LEU384C, LEU3A, LEU3C, LYS272A, LYS272C, LYS290A, LYS290C, LYS307A, LYS307C, LYS312A, LYS312C, LYS326A, LYS326C, LYS335A, LYS335C, LYS376A, LYS376C, PHE284A, PHE284C, PHE289A, PHE289C, PHE318A, PHE318C, PHE328A, PHE328C, PHE5A, PHE5C, PRO280A, PRO280C, SER288A, SER288C, SER372A, SER372C, THR296A, THR296C, THR371A, THR371C, TRP4A, TRP4C, TYR266C, TYR270A, TYR270C, TYR305A, TYR305C, TYR80A, VAL287A, VAL287C, VAL378A, VAL378C, VAL387A, VAL387C
• A-D: ARG279A, ARG279D, GLN342D, GLU283A, GLU283D, GLU285A, GLU285D, GLY286A, GLY286D, ILE281A, ILE281D, LYS290A, LYS290D, PHE277D, PHE284A, PHE284D, PHE289A, PHE289D, SER288A, SER288D, VAL287A, VAL287D
• B-C: ARG279B, ARG279C, GLU283B, GLU283C, GLU285B, GLU285C, GLY286B, GLY286C, ILE281B, ILE281C, LYS290B, LYS290C, PHE284B, PHE284C, PHE289B, PHE289C, SER288B, SER288C, VAL287B, VAL287C
• B-D: ALA267B, ALA267D, ALA269B, ALA269D, ALA271B, ALA271D, ALA282B, ALA282D, ALA292B, ALA292D, ALA294B, ALA294D, ALA295B, ALA295D, ALA300B, ALA300D, ALA301B, ALA301D, ALA308B, ALA308D, ALA309B, ALA309D, ALA314B, ALA314D, ALA323B, ALA323D, ALA325B, ALA325D, ALA329B, ALA329D, ALA332B, ALA332D, ALA380B, ALA380D, ALA386B, ALA386D, ARG12B, ARG12D, ARG302B, ARG302D, ARG316B, ARG316D, ARG381B, ARG381D, ARG382B, ARG382D, ARG69B, ARG69D, ASP265B, ASP265D, ASP313B, ASP313D, GLN261B, GLN261D, GLN324B, GLN324D, GLU283B, GLU283D, GLU285B, GLU285D, GLU293B, GLU293D, GLU297B, GLU297D, GLU299B, GLU299D, GLU310B, GLU310D, GLU321B, GLU321D, GLU331B, GLU331D, GLU373B, GLU373D, GLU385B, GLU385D, GLU6B, GLU6D, GLU7D, GLY273B, GLY273D, GLY286B, GLY286D, GLY315B, GLY315D, ILE281B, ILE281D, ILE374B, ILE374D, ILE379B, ILE379D, LEU264B, LEU264D, LEU268B, LEU268D, LEU291B, LEU291D, LEU298B, LEU298D, LEU303B, LEU303D, LEU304B, LEU304D, LEU306B, LEU306D, LEU311B, LEU311D, LEU320B, LEU320D, LEU327B, LEU327D, LEU375B, LEU375D, LEU377B, LEU377D, LEU383B, LEU383D, LEU384B, LEU384D, LEU3B, LEU3D, LYS272B, LYS272D, LYS290B, LYS290D, LYS307B, LYS307D, LYS312B, LYS312D, LYS326B, LYS326D, LYS335B, LYS376B, LYS376D, PHE284B, PHE284D, PHE289B, PHE289D, PHE318B, PHE328B, PHE328D, PHE5B, PHE5D, PRO280B, PRO280D, PRO317D, SER288B, SER288D, SER372B, SER372D, THR296B, THR296D, THR371B, THR371D, TRP4B, TRP4D, TYR270B, TYR270D, TYR305B, TYR305D, TYR80B, VAL287B, VAL287D, VAL378B, VAL378D, VAL387B, VAL387D
• C-D: ALA136C, ALA136D, ALA137C, ALA137D, ALA138C, ALA138D, ALA276C, ALA276D, ALA340C, ALA340D, ALA362C, ALA362D, ALA84D, ARG203D, ARG274C, ARG274D, ARG279C, ARG279D, ARG357C, ARG357D, ARG35C, ARG35D, ARG360C, ARG360D, ARG363C, ARG363D, ARG366C, ARG366D, ARG381C, ARG381D, ASP135C, ASP135D, ASP338C, ASP338D, ASP34D, ASP352C, ASP352D, ASP361C, ASP361D, CYS337C, CYS337D, GLN157C, GLN157D, GLN217C, GLN217D, GLN342C, GLN342D, GLU129C, GLU129D, GLU181C, GLU181D, GLU205C, GLU205D, GLU206C, GLU206D, GLU275C, GLU275D, GLU285C, GLU285D, GLU331C, GLU331D, GLU339C, GLU339D, GLU356C, GLU356D, GLU373C, GLU373D, GLY131C, GLY131D, GLY133C, GLY133D, GLY209C, GLY209D, GLY278C, GLY278D, GLY286C, GLY286D, GLY345C, GLY345D, GLY346C, GLY346D, GLY348C, GLY348D, GLY368C, GLY368D, GLY370C, GLY370D, GLY83C, ILE281C, ILE281D, ILE341C, ILE341D, ILE343C, ILE343D, ILE367C, ILE367D, ILE374C, ILE374D, LEU208C, LEU208D, LEU210C, LEU210D, LEU259C, LEU327C, LEU327D, LEU344C, LEU344D, LEU364C, LEU364D, LEU375C, LEU375D, LEU377C, LEU377D, LEU87C, LEU87D, LYS140C, LYS140D, LYS183C, LYS183D, LYS204C, LYS204D, LYS207C, LYS207D, LYS290C, LYS290D, LYS326C, LYS326D, LYS335C, LYS335D, LYS351C, LYS351D, LYS376C, LYS376D, MET255D, PHE158C, PHE158D, PHE238C, PHE238D, PHE277C, PHE277D, PHE284C, PHE284D, PRO130C, PRO130D, PRO180C, PRO180D, SER132C, SER132D, SER134C, SER134D, SER213C, SER213D, SER330C, SER330D, SER372C, SER372D, THR128C, THR128D, THR211C, THR211D, THR215C, THR215D, THR365C, THR365D, THR371C, THR371D, TRP359C, TRP359D, TYR270C, TYR270D, TYR347C, TYR347D, TYR349C, TYR349D, TYR353C, TYR353D, TYR358C, VAL287C, VAL287D, VAL334C, VAL334D, VAL350C, VAL350D, VAL355C, VAL355D, VAL378C