2CX5

crystal structure of a putative trans-editing enzyme for prolyl trna synthetase

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 71
  • Norm. En. per Res.: -2.8145
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-37.6985	0.5529	-162.682	-199.8276	71	8	8	7669	0	18	18
A-C	-26.3974	11.1838	-183.227	-198.4405	82	9	2	7371	0	21	16
A-D	0.0	-2.5783	-0.7296	-3.3079	7	0	0	165	0	1	3
B-C	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
C-D	0.0	0.7299	-44.0083	-43.2784	56	2	0	2595	0	6	8

Interface residues

• A-B: ALA135A, ALA135B, ALA29A, ALA29B, ALA37A, ALA37B, ALA38A, ALA38B, ALA40A, ALA40B, ALA43A, ALA43B, ALA7A, ALA7B, ARG134A, ARG134B, ARG138A, ARG138B, ARG8A, ARG8B, GLN11A, GLN11B, GLN39A, GLN39B, GLU125A, GLU125B, GLU15A, GLU26A, GLU26B, GLU36A, GLU36B, GLY20A, GLY20B, GLY42A, GLY42B, HIS21A, HIS21B, LEU136A, LEU136B, LEU22A, LEU22B, LEU27A, LEU27B, LEU3A, LEU3B, LYS23A, LYS23B, PHE137A, PHE137B, PHE19A, PRO28A, PRO28B, PRO5A, PRO5B, SER2A, SER2B, SER30A, SER30B, SER4A, SER4B, THR132A, THR31A, THR31B, TRP127A, TRP127B, VAL24A, VAL24B, VAL25A, VAL25B, VAL41A, VAL41B
• A-C: ALA114A, ALA13A, ALA146A, ALA150A, ALA60A, ALA76C, ALA87C, ARG17A, ARG70C, ARG78C, ARG85C, ARG9A, ASN109A, ASN69C, ASP72C, GLN151A, GLN86C, GLU143A, GLU157C, GLU15A, GLU57C, GLU90C, GLU91C, GLY101C, GLY107A, GLY12A, GLY149A, GLY158C, GLY18A, GLY20A, GLY56C, GLY59A, GLY59C, GLY74C, GLY82C, GLY97A, HIS108A, HIS21A, ILE100C, LEU112A, LEU144A, LEU145A, LEU147A, LEU14A, LEU155C, LEU22A, LEU52C, LEU62A, LEU71C, LEU73C, LEU84C, LEU95A, LYS142A, LYS156C, LYS50C, LYS58A, LYS58C, LYS75C, PHE19A, PHE54C, PRO105A, PRO111A, PRO113A, PRO83C, PRO89C, SER51C, THR110A, THR140A, THR148A, THR16A, THR77C, THR88C, THR96A, TYR61A, TYR61C, VAL103C, VAL106A, VAL10A, VAL53C, VAL55C, VAL65C, VAL92C
• A-D: GLU15D, GLY18D, GLY20D, HIS21D, LYS58A, PHE19D, THR16D
• B-C: ARG70C, GLN39B
• C-D: ALA114C, ALA114D, ALA13D, ALA146C, ALA146D, ALA150C, ALA60C, ALA60D, ARG17C, ARG17D, ASN109D, GLN151C, GLN151D, GLU143C, GLU57C, GLU57D, GLY107D, GLY12D, GLY149C, GLY149D, GLY18D, GLY56D, GLY59C, GLY59D, GLY81C, GLY82C, HIS108D, LEU112C, LEU112D, LEU144C, LEU145C, LEU147C, LEU147D, LEU79C, LEU95D, LYS142C, LYS58C, LYS58D, PHE19C, PHE19D, PRO111C, PRO111D, PRO113C, PRO113D, PRO83C, THR110C, THR110D, THR148C, THR16D, TYR115C, TYR61C, TYR61D, VAL106D, VAL152C, VAL80C, VAL80D