2CLW

crystal structure of human ubiquitin-conjugating enzyme ubch5b

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 59
  • Norm. En. per Res.: -2.7776
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.1541	-0.1541	4	0	0	28	0	0	0
A-D	-3.3821	-17.8601	-72.8324	-94.0747	62	3	1	3769	1	27	21
B-C	0.0	0.0	-0.0369	-0.0369	4	0	0	18	0	0	0
B-D	-30.365	-8.1839	-125.33	-163.8789	59	15	2	5859	2	24	23
C-D	0.0	-22.0258	-31.4906	-53.5164	20	1	0	1167	1	4	3

Interface residues

• A-B: ASN81B, GLN92A, SER80B, SER91A
• A-D: ALA19D, ALA2A, ALA96A, ALA96D, ARG131D, ARG15A, ARG5A, ASN114D, ASN11A, ASN41D, ASP112D, ASP116D, ASP117D, ASP12A, ASP16A, ASP42D, ASP59A, ASP87D, CYS107D, CYS111D, GLN92A, GLN92D, GLU9A, GLY-1A, ILE106D, ILE88A, ILE88D, LEU103D, LEU104D, LEU109D, LEU110D, LEU86D, LEU97A, LEU97D, LYS101A, LYS101D, LYS128D, LYS4A, LYS8A, MET1A, PHE62A, PRO113D, PRO115D, PRO40D, PRO61A, PRO95A, SER0A, SER100A, SER100D, SER105D, SER108D, SER43D, SER94A, SER94D, THR58A, THR98A, THR98D, TRP93A, TRP93D, TYR127D, TYR60A, VAL102D
• B-C: ASN81C, GLN92B, SER80C, SER91B
• B-D: ALA124B, ALA138B, ALA14D, ALA19D, ALA23D, ALA35D, ARG125B, ARG136B, ARG139B, ARG15D, ASN11D, ASP117B, ASP12D, ASP130B, ASP16D, CYS21D, GLN20D, GLN34D, GLU122B, GLU132B, GLU140B, GLY24D, GLY27D, HIS32D, HIS75B, HIS7D, ILE123B, ILE126B, ILE137B, ILE37D, ILE54D, LEU103D, LEU10D, LEU119B, LEU13D, LYS133B, LYS144B, LYS8D, MET30D, MET38D, PRO118B, PRO121B, PRO17D, PRO18D, PRO25D, PRO76B, SER100D, SER22D, SER80B, THR129B, THR36D, TRP141B, TRP33D, TYR134B, TYR145B, TYR74B, VAL120B, VAL26D, VAL49D
• C-D: ALA146D, ARG72D, ASP28C, ASP29C, GLN143D, GLN34C, GLU140D, GLY27C, HIS32C, HIS55C, LYS144D, MET147D, PRO25C, THR142D, THR70C, THR70D, THR71D, TRP141D, TYR145D, VAL26C