2CJR

crystal structure of oligomerization domain of sars coronavirus nucleocapsid protein.

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 170
  • Norm. En. per Res.: -6.6247
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-208.8562	-34.8071	-882.539	-1126.2023	170	43	28	31968	0	36	30
A-G	0.0	2.0489	-8.0888	-6.0399	14	0	0	645	0	9	8
A-H	0.0	0.0	-0.003	-0.003	4	0	0	5	0	4	5
B-C	-26.7057	13.1944	-92.9067	-106.4181	58	8	0	4576	0	8	18
B-F	0.0	0.0	-5.0261	-5.0261	8	0	0	316	0	0	0
B-H	0.0	3.5567	-10.4148	-6.8581	14	0	0	657	0	12	11
C-D	-222.5227	-44.7968	-829.498	-1096.8174	173	73	30	32522	0	33	30
C-E	0.0	0.0	-14.7562	-14.7562	16	2	0	723	0	14	11
C-G	0.0	0.0	-0.1503	-0.1503	2	0	0	42	0	0	0
D-E	0.0	0.0	-0.0017	-0.0017	2	0	0	1	0	4	5
D-F	-4.4198	-9.188	-31.0507	-44.6585	14	2	0	1492	0	12	8
E-F	-181.8912	-15.7017	-863.747	-1061.3399	175	76	28	32427	0	35	30
F-G	-9.5208	10.7202	-69.0565	-67.8571	43	4	0	2903	0	6	18
G-H	-215.4539	-6.425	-761.079	-982.9579	167	81	28	31896	0	34	32

Interface residues

• A-B: ALA265A, ALA265B, ALA274A, ALA274B, ALA306A, ALA306B, ALA309A, ALA309B, ALA312A, ALA312B, ALA314A, ALA314B, ALA337A, ALA337B, ARG260A, ARG260B, ARG263A, ARG263B, ARG277A, ARG277B, ARG278A, ARG278B, ARG320A, ARG320B, ASN270A, ASN286A, ASN286B, ASN350A, ASN350B, ASN355A, ASN355B, ASP298A, ASP341A, ASP341B, ASP342A, ASP342B, ASP344A, ASP359A, ASP359B, GLN261A, GLN261B, GLN282A, GLN282B, GLN284A, GLN284B, GLN295A, GLN304A, GLN304B, GLN307A, GLN307B, GLU281A, GLU281B, GLU324A, GLU324B, GLY276A, GLY276B, GLY279A, GLY279B, GLY285A, GLY285B, GLY288A, GLY288B, GLY296A, GLY296B, GLY317A, GLY317B, GLY322A, GLY322B, GLY329A, GLY329B, GLY336A, GLY336B, HIS335A, HIS335B, HIS357A, HIS357B, ILE293A, ILE293B, ILE305A, ILE305B, ILE321A, ILE321B, ILE338A, ILE338B, ILE352A, ILE352B, ILE358A, ILE358B, LEU292A, LEU292B, LEU332A, LEU332B, LEU340A, LEU340B, LEU353A, LEU354A, LEU354B, LYS258A, LYS258B, LYS262A, LYS262B, LYS339A, LYS339B, LYS348A, LYS362A, MET318A, MET318B, MET323A, MET323B, PHE275A, PHE275B, PHE287A, PHE287B, PHE308A, PHE308B, PHE315A, PHE315B, PHE316A, PHE316B, PHE347A, PHE347B, PRO259A, PRO259B, PRO280A, PRO280B, PRO303A, PRO303B, PRO310A, PRO310B, PRO327A, PRO327B, SER311A, SER311B, SER313A, SER313B, SER319A, SER319B, SER328A, SER328B, THR264A, THR264B, THR266A, THR266B, THR272B, THR283A, THR283B, THR297A, THR297B, THR326A, THR326B, THR330A, THR330B, THR333A, THR333B, TRP302A, TRP302B, TRP331A, TRP331B, TYR269A, TYR269B, TYR334A, TYR334B, TYR361A, TYR361B, VAL271A, VAL271B, VAL325A, VAL325B, VAL351A, VAL351B
• A-G: ALA255G, ASP342A, ASP344A, GLN346A, LYS257G, LYS258G, LYS262G, LYS343A, LYS348A, PHE347A, PRO259G, PRO345A, SER256G, TYR269G
• A-H: GLN307H, GLN346A, LYS343A, LYS343H
• B-C: ALA253B, ALA253C, ALA265C, ALA274B, ALA274C, ARG277B, ARG277C, ARG278B, ARG278C, ARG294B, ARG294C, ASN270B, ASN270C, ASP289C, ASP291B, ASP291C, ASP298B, ASP298C, GLN268B, GLN268C, GLN273B, GLN273C, GLN284B, GLN284C, GLN290B, GLN290C, GLN295B, GLN295C, GLU281B, GLU281C, GLY276B, GLY276C, GLY279B, GLY288C, GLY296C, ILE293B, ILE293C, LYS267B, LYS267C, LYS362B, LYS362C, PHE364B, PHE364C, PRO280B, PRO365B, PRO365C, THR266B, THR266C, THR272B, THR272C, THR363B, THR363C, TYR269B, TYR269C, TYR361B, TYR361C, VAL271B, VAL271C
• B-F: GLY329B, GLY329F, PRO327B, PRO327F, SER328B, SER328F, THR326B, THR326F
• B-H: ALA255B, ASP342H, ASP344H, GLN346H, GLU254B, LYS257B, LYS258B, LYS262B, LYS343H, LYS348H, PHE347H, PRO259B, PRO345H, SER256B
• C-D: ALA265C, ALA265D, ALA274C, ALA274D, ALA306C, ALA306D, ALA309C, ALA309D, ALA312C, ALA312D, ALA314C, ALA314D, ALA337C, ALA337D, ARG260C, ARG260D, ARG263C, ARG263D, ARG277C, ARG277D, ARG278C, ARG278D, ARG320C, ARG320D, ASN270D, ASN286C, ASN286D, ASN350C, ASN350D, ASN355C, ASN355D, ASP298D, ASP341C, ASP341D, ASP342C, ASP342D, ASP344C, ASP359C, ASP359D, GLN261C, GLN261D, GLN282C, GLN282D, GLN284C, GLN284D, GLN304C, GLN304D, GLN307C, GLN307D, GLU281C, GLU281D, GLU324C, GLU324D, GLY276C, GLY276D, GLY279C, GLY279D, GLY285C, GLY285D, GLY288C, GLY288D, GLY296C, GLY296D, GLY317C, GLY317D, GLY322C, GLY322D, GLY329C, GLY329D, GLY336C, GLY336D, HIS335C, HIS335D, HIS357C, HIS357D, ILE293C, ILE293D, ILE305C, ILE305D, ILE321C, ILE321D, ILE338C, ILE338D, ILE352C, ILE352D, ILE358C, ILE358D, LEU292C, LEU292D, LEU332C, LEU332D, LEU340C, LEU340D, LEU353C, LEU353D, LEU354C, LEU354D, LYS258C, LYS258D, LYS262C, LYS262D, LYS339C, LYS339D, LYS343C, LYS348C, LYS348D, LYS356C, LYS356D, LYS362C, LYS362D, MET318C, MET318D, MET323C, MET323D, PHE275C, PHE275D, PHE287C, PHE287D, PHE308C, PHE308D, PHE315C, PHE315D, PHE316C, PHE316D, PHE347C, PHE347D, PRO259C, PRO259D, PRO280C, PRO280D, PRO303C, PRO303D, PRO310C, PRO310D, PRO327D, SER311C, SER311D, SER313C, SER313D, SER319C, SER319D, SER328C, SER328D, THR264C, THR264D, THR266C, THR266D, THR283C, THR283D, THR297C, THR297D, THR326C, THR326D, THR330C, THR330D, THR333C, THR333D, TRP302C, TRP302D, TRP331C, TRP331D, TYR269C, TYR269D, TYR334C, TYR334D, TYR361C, TYR361D, VAL271C, VAL271D, VAL325C, VAL325D, VAL351C, VAL351D
• C-E: ALA255C, ARG263C, ASP341E, ASP342E, ASP344E, ASP349E, GLN346E, GLU254C, LYS257C, LYS258C, LYS262C, LYS343E, PHE347E, PRO259C, PRO345E, SER256C
• C-G: PRO327C, PRO327G
• D-E: GLN307D, GLN346E
• D-F: ALA255F, ASP341D, ASP342D, ASP344D, GLN346D, LYS257F, LYS258F, LYS262F, LYS343D, LYS348D, PHE347D, PRO259F, PRO345D, SER256F
• E-F: ALA265E, ALA265F, ALA274E, ALA274F, ALA306E, ALA306F, ALA309E, ALA309F, ALA312E, ALA312F, ALA314E, ALA314F, ALA337E, ALA337F, ARG260E, ARG260F, ARG263E, ARG263F, ARG277E, ARG277F, ARG278E, ARG278F, ARG320E, ARG320F, ASN270E, ASN270F, ASN286E, ASN286F, ASN350E, ASN350F, ASN355E, ASN355F, ASP298F, ASP341E, ASP341F, ASP342E, ASP342F, ASP344E, ASP349E, ASP359E, ASP359F, GLN261E, GLN261F, GLN282E, GLN282F, GLN284E, GLN284F, GLN304E, GLN304F, GLN307E, GLN307F, GLU281E, GLU281F, GLU324E, GLU324F, GLY276E, GLY276F, GLY279E, GLY279F, GLY285E, GLY285F, GLY288E, GLY288F, GLY296E, GLY296F, GLY317E, GLY317F, GLY322E, GLY322F, GLY329E, GLY329F, GLY336E, GLY336F, HIS335E, HIS335F, HIS357E, HIS357F, ILE293E, ILE293F, ILE305E, ILE305F, ILE321E, ILE321F, ILE338E, ILE338F, ILE352E, ILE352F, ILE358E, ILE358F, LEU292E, LEU292F, LEU332E, LEU332F, LEU340E, LEU340F, LEU353E, LEU353F, LEU354E, LEU354F, LYS258E, LYS258F, LYS262E, LYS262F, LYS339E, LYS339F, LYS348E, LYS348F, LYS356E, LYS356F, LYS362E, MET318E, MET318F, MET323E, MET323F, PHE275E, PHE275F, PHE287E, PHE287F, PHE308E, PHE308F, PHE315E, PHE315F, PHE316E, PHE316F, PHE347E, PHE347F, PRO259E, PRO259F, PRO280E, PRO280F, PRO303E, PRO303F, PRO310E, PRO310F, PRO327E, SER311E, SER311F, SER313E, SER313F, SER319E, SER319F, SER328E, SER328F, THR264E, THR264F, THR266E, THR266F, THR272E, THR272F, THR283E, THR283F, THR297E, THR297F, THR326E, THR326F, THR330E, THR330F, THR333E, THR333F, TRP302E, TRP302F, TRP331E, TRP331F, TYR269E, TYR269F, TYR334E, TYR334F, TYR361E, TYR361F, VAL271E, VAL271F, VAL325E, VAL325F, VAL351E, VAL351F
• F-G: ALA252F, ALA253F, ALA274F, ARG277F, ARG277G, ARG278F, ARG294F, ARG294G, ASN270F, ASN270G, ASP291F, ASP291G, GLN268F, GLN268G, GLN273F, GLN273G, GLN284G, GLN290F, GLN290G, GLN295F, GLN295G, GLU281G, GLY276F, GLY276G, GLY279G, GLY296F, ILE293F, ILE293G, LYS267F, LYS267G, LYS362G, PRO280F, PRO280G, THR266F, THR266G, THR272F, THR272G, THR283G, TYR269F, TYR269G, TYR361G, VAL271F, VAL271G
• G-H: ALA265G, ALA265H, ALA274G, ALA274H, ALA306G, ALA306H, ALA309G, ALA309H, ALA312G, ALA312H, ALA314G, ALA314H, ALA337G, ALA337H, ARG260G, ARG260H, ARG263G, ARG263H, ARG277G, ARG277H, ARG278G, ARG278H, ARG320G, ARG320H, ASN270H, ASN286G, ASN286H, ASN350G, ASN350H, ASN355G, ASN355H, ASP298G, ASP298H, ASP341G, ASP341H, ASP342G, ASP342H, ASP359G, ASP359H, GLN261G, GLN261H, GLN282G, GLN282H, GLN284G, GLN284H, GLN295G, GLN304G, GLN304H, GLN307G, GLN307H, GLU281G, GLU281H, GLU324G, GLU324H, GLY276G, GLY276H, GLY279G, GLY279H, GLY285G, GLY285H, GLY288G, GLY288H, GLY296G, GLY296H, GLY317G, GLY317H, GLY322G, GLY322H, GLY329G, GLY329H, GLY336G, GLY336H, HIS335G, HIS335H, HIS357G, HIS357H, ILE293G, ILE293H, ILE305G, ILE305H, ILE321G, ILE321H, ILE338G, ILE338H, ILE352H, ILE358G, ILE358H, LEU292G, LEU292H, LEU332G, LEU332H, LEU340G, LEU340H, LEU353H, LEU354G, LEU354H, LYS257G, LYS258G, LYS258H, LYS262G, LYS262H, LYS339G, LYS339H, LYS348H, LYS362H, MET318G, MET318H, MET323G, MET323H, PHE275G, PHE275H, PHE287G, PHE287H, PHE308G, PHE308H, PHE315G, PHE315H, PHE316G, PHE316H, PHE347G, PHE347H, PRO259G, PRO259H, PRO280G, PRO280H, PRO303G, PRO303H, PRO310G, PRO310H, SER311G, SER311H, SER313G, SER313H, SER319G, SER319H, SER328G, SER328H, THR264G, THR264H, THR266G, THR266H, THR283G, THR283H, THR297G, THR297H, THR326G, THR326H, THR330G, THR330H, THR333G, THR333H, TRP302G, TRP302H, TRP331G, TRP331H, TYR269G, TYR269H, TYR334G, TYR334H, TYR361G, TYR361H, VAL271G, VAL271H, VAL325G, VAL325H, VAL351G, VAL351H