2CG9

crystal structure of an hsp90-sba1 closed chaperone complex

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-X
  • Int. Res.: 95
  • Norm. En. per Res.: -3.1133
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-93.7623	-36.7891	-814.799	-945.3504	308	78	48	36368	1	41	38
A-X	-36.039	-44.8564	-214.869	-295.7644	95	20	4	9387	2	51	19
A-Y	-19.6072	-30.6473	-63.3316	-113.5861	53	3	0	2747	4	18	23
B-X	-15.1797	-37.246	-57.1595	-109.5852	52	6	0	2719	4	20	22
B-Y	-9.8184	-21.958	-200.545	-232.3214	95	10	4	8708	2	47	20

Interface residues

• A-B: ALA10A, ALA10B, ALA152A, ALA152B, ALA2A, ALA2B, ALA481A, ALA481B, ALA574A, ALA574B, ALA576A, ALA576B, ALA595A, ALA595B, ALA597A, ALA597B, ALA650A, ALA650B, ALA665A, ALA665B, ALA97A, ALA97B, ARG380A, ARG380B, ARG591A, ARG591B, ARG628A, ARG628B, ARG667A, ARG667B, ARG670A, ARG670B, ASN151A, ASN151B, ASN21A, ASN21B, ASN26A, ASN26B, ASN377A, ASN377B, ASN386A, ASN386B, ASN669A, ASN669B, ASN677A, ASN677B, ASN91A, ASN91B, ASP489A, ASP503A, ASP506A, ASP573A, ASP573B, ASP641A, ASP641B, ASP659A, ASP659B, GLN119A, GLN119B, GLN14A, GLN14B, GLN384A, GLN384B, GLN385A, GLN385B, GLN596A, GLN596B, GLN9A, GLN9B, GLU11A, GLU11B, GLU149A, GLU149B, GLU162A, GLU162B, GLU355A, GLU360A, GLU381A, GLU381B, GLU431A, GLU477A, GLU477B, GLU483A, GLU483B, GLU4A, GLU4B, GLU624A, GLU624B, GLU648A, GLU648B, GLU660A, GLU660B, GLU7A, GLU7B, GLY121A, GLY121B, GLY123A, GLY123B, GLY153A, GLY153B, GLY154A, GLY154B, GLY476A, GLY476B, GLY655A, GLY655B, GLY675A, GLY675B, GLY94A, GLY94B, ILE12A, ILE12B, ILE147A, ILE147B, ILE19A, ILE19B, ILE388A, ILE388B, ILE505A, ILE505B, ILE592A, ILE592B, ILE621A, ILE621B, ILE622A, ILE622B, ILE668A, ILE668B, ILE672A, ILE672B, ILE90A, ILE90B, ILE96A, ILE96B, LEU15A, LEU15B, LEU160A, LEU160B, LEU18A, LEU18B, LEU374A, LEU374B, LEU376A, LEU376B, LEU378A, LEU378B, LEU383A, LEU383B, LEU427A, LEU488A, LEU625A, LEU625B, LEU642A, LEU642B, LEU645A, LEU645B, LEU646A, LEU646B, LEU651A, LEU651B, LEU652A, LEU652B, LEU658A, LEU658B, LEU671A, LEU671B, LEU674A, LEU674B, LEU676A, LEU676B, LEU93A, LEU93B, LYS102A, LYS102B, LYS27A, LYS27B, LYS335B, LYS336B, LYS387A, LYS387B, LYS423A, LYS423B, LYS480A, LYS480B, LYS484A, LYS484B, LYS594A, LYS594B, LYS640A, LYS640B, LYS86A, LYS86B, LYS98A, LYS98B, MET105A, MET105B, MET16A, MET16B, MET382A, MET382B, PHE120A, PHE120B, PHE124A, PHE124B, PHE128A, PHE128B, PHE156A, PHE156B, PHE329B, PHE487A, PHE487B, PHE656A, PHE656B, PHE664A, PHE664B, PHE6A, PHE6B, PHE8A, PHE8B, PRO359A, PRO375A, PRO375B, PRO486A, PRO486B, PRO504A, PRO504B, PRO575A, PRO575B, PRO620A, PRO620B, PRO661A, PRO661B, SER150A, SER150B, SER155A, SER155B, SER17A, SER17B, SER25A, SER25B, SER334B, SER379A, SER379B, SER3A, SER3B, SER478A, SER478B, SER485A, SER485B, SER619A, SER619B, SER654A, SER654B, SER657A, SER657B, SER663A, SER663B, SER666A, SER666B, SER673A, SER673B, SER99A, SER99B, THR101A, THR101B, THR13A, THR13B, THR157A, THR157B, THR159A, THR159B, THR22A, THR22B, THR502A, THR5A, THR5B, THR638A, THR638B, THR649A, THR649B, THR653A, THR653B, THR662A, THR662B, THR95A, THR95B, TRP148A, TRP148B, TRP361A, TYR125A, TYR125B, TYR146A, TYR146B, TYR24A, TYR24B, TYR508A, VAL122A, VAL122B, VAL134A, VAL134B, VAL158A, VAL158B, VAL23A, VAL23B, VAL482A, VAL482B, VAL639A, VAL639B
• A-X: ALA103A, ALA107A, ALA110A, ALA112A, ALA127X, ALA13X, ARG106X, ARG15X, ARG318A, ARG346A, ASN377A, ASN386A, ASN395A, ASP113A, ASP120X, ASP122X, ASP126X, ASP128X, ASP131X, ASP20X, ASP34X, ASP373A, GLN119A, GLN14X, GLN314A, GLN384A, GLN385A, GLN66X, GLU106A, GLU132X, GLU134X, GLU22X, GLU312A, GLU316A, GLU372A, GLY111A, GLY118A, GLY313A, HIS68X, ILE117A, ILE117X, ILE32X, ILE388A, ILE392A, ILE69X, LEU107X, LEU108A, LEU27X, LEU315A, LEU374A, LEU376A, LEU383A, LEU67X, LYS102A, LYS111X, LYS113X, LYS118X, LYS123X, LYS387A, LYS390A, LYS394A, MET105A, MET116A, MET389A, PHE104A, PHE121X, PHE317A, PHE8A, PRO105X, PRO115X, PRO21X, PRO375A, SER109A, SER115A, SER16X, SER17X, SER31X, SER371A, THR101A, THR108X, THR119X, THR18X, THR19X, TRP104X, TRP124X, TRP12X, TYR114X, TYR116X, TYR65X, VAL112X, VAL114A, VAL125X, VAL26X, VAL30X, VAL391A
• A-Y: ALA131A, ALA152A, ALA33Y, ALA85Y, ARG133A, ASN151A, ASN21A, ASN86Y, ASP120Y, ASP122Y, ASP132A, ASP179A, ASP180A, ASP34Y, GLN14A, GLN181A, GLU11A, GLY153A, GLY154A, GLY87Y, HIS63Y, ILE12A, ILE20A, ILE32Y, LEU129A, LEU177A, LEU27Y, LEU92Y, LYS123Y, LYS178A, LYS27A, LYS54Y, LYS73A, LYS83Y, MET16A, MET81Y, PHE121Y, PHE128A, PHE176A, SER150A, SER155A, SER16Y, SER17A, SER25A, SER31Y, SER53Y, THR13A, THR29Y, TYR65Y, TYR90Y, VAL134A, VAL23A, VAL84Y
• B-X: ALA131B, ALA152B, ALA33X, ALA85X, ARG133B, ASN151B, ASN21B, ASN86X, ASP120X, ASP122X, ASP132B, ASP179B, ASP180B, ASP34X, GLN14B, GLN181B, GLY153B, GLY154B, GLY87X, HIS63X, ILE12B, ILE20B, ILE32X, LEU129B, LEU177B, LEU27X, LEU92X, LYS123X, LYS178B, LYS27B, LYS54X, LYS73B, LYS83X, MET16B, MET81X, PHE121X, PHE128B, PHE176B, SER150B, SER155B, SER16X, SER17B, SER25B, SER31X, SER53X, THR13B, THR29X, TYR65X, TYR90X, VAL134B, VAL23B, VAL84X
• B-Y: ALA103B, ALA107B, ALA110B, ALA112B, ALA127Y, ALA13Y, ARG106Y, ARG15Y, ARG318B, ARG346B, ASN377B, ASN386B, ASP113B, ASP120Y, ASP122Y, ASP126Y, ASP128Y, ASP20Y, ASP34Y, ASP373B, GLN119B, GLN14Y, GLN314B, GLN384B, GLN385B, GLN66Y, GLU106B, GLU110Y, GLU132Y, GLU22Y, GLU312B, GLU316B, GLU372B, GLY111B, GLY118B, GLY313B, HIS68Y, ILE117B, ILE117Y, ILE32Y, ILE388B, ILE392B, ILE69Y, LEU107Y, LEU108B, LEU27Y, LEU315B, LEU374B, LEU376B, LEU383B, LEU67Y, LYS102B, LYS111Y, LYS113Y, LYS118Y, LYS123Y, LYS387B, LYS390B, LYS394B, MET105B, MET116B, MET389B, PHE104B, PHE121Y, PHE8B, PRO105Y, PRO115Y, PRO21Y, PRO375B, SER109B, SER115B, SER16Y, SER17Y, SER31Y, SER371B, THR101B, THR108Y, THR119Y, THR18Y, THR19Y, THR278B, TRP104Y, TRP124Y, TRP12Y, TYR103Y, TYR114Y, TYR116Y, TYR47B, TYR65Y, VAL112Y, VAL114B, VAL125Y, VAL26Y, VAL30Y, VAL391B