2C9W

crystal structure of socs-2 in complex with elongin-b and elongin-c at 1.9a resolution

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 93
  • Norm. En. per Res.: -4.5566
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-47.6669	-47.6669	25	0	2	1986	0	0	1
A-C	-23.5122	0.0	-253.827	-277.3392	81	4	14	10819	0	14	7
B-C	-91.4718	-2.041	-330.253	-423.7657	93	13	6	12516	1	23	24

Interface residues

• A-B: ALA177A, ASN172A, ASP101B, CYS167A, CYS174A, GLN70B, GLU98B, GLY176A, GLY180A, ILE171A, ILE178A, LEU166A, LEU181A, LEU183A, LEU99B, LYS104B, LYS173A, MET103B, PRO100B, PRO182A, PRO97B, THR170A, THR175A, TRP179A, VAL102B
• A-C: ALA100C, ALA106C, ALA107C, ALA160A, ALA65A, ALA96C, ARG168A, ARG186A, ARG82C, ASN108C, ASN172A, ASP111C, CYS112C, CYS167A, CYS174A, CYS74C, GLN164A, GLU102C, GLU64A, GLU89C, GLU92C, GLU98C, GLY180A, GLY47A, HIS165A, ILE171A, ILE178A, ILE90C, ILE95C, ILE99C, LEU101C, LEU103C, LEU104C, LEU110C, LEU156A, LEU163A, LEU166A, LEU169A, LEU181A, LEU183A, LEU187A, LEU191A, LEU62A, LEU70C, LYS154A, LYS173A, LYS188A, LYS61A, LYS72C, LYS80C, MET105C, MET75C, PHE109C, PHE77C, PHE93C, PRO155A, PRO161A, PRO182A, PRO184A, PRO66A, PRO91C, PRO94C, PRO97C, SER159A, SER162A, SER39C, THR158A, THR170A, THR175A, THR38C, THR69A, THR84C, TRP50A, TYR157A, TYR190A, TYR76C, TYR79C, TYR83C, VAL69C, VAL73C, VAL81C
• B-C: ALA100C, ALA18B, ALA71B, ALA73B, ALA96C, ARG68B, ARG82C, ARG8B, ARG9B, ASP17B, ASP25C, ASP2B, CYS74C, GLN70B, GLU102C, GLU28C, GLU89C, GLU91B, GLU92C, GLU98B, GLU98C, GLY26C, GLY33B, HIS10B, HIS27C, HIS35C, HIS68C, ILE14B, ILE22C, ILE30B, ILE30C, ILE34B, ILE65C, ILE7B, ILE90B, ILE90C, ILE95C, ILE99C, LEU101C, LEU21C, LEU35B, LEU5B, LEU70C, LEU99B, LYS104B, LYS11B, LYS20C, LYS32C, LYS72C, LYS80C, MET103B, MET17C, MET6B, MET75C, PHE15B, PHE29C, PHE4B, PHE77C, PHE93B, PHE93C, PRO100B, PRO66C, PRO69B, PRO72B, PRO91C, PRO92B, PRO94C, PRO96B, PRO97B, PRO97C, SER23C, SER24C, SER67C, SER71C, SER94B, SER95B, THR12B, THR13B, THR16B, THR74B, THR78C, TYR18C, TYR76C, TYR79C, TYR83C, VAL102B, VAL19C, VAL31B, VAL31C, VAL3B, VAL69C, VAL73C, VAL81C