2C7N

human rabex-5 residues 1-74 in complex with ubiquitin

• Total interactions analyzed: 66
• Total true interactions: 20
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 58
  • Norm. En. per Res.: -5.6925
• Hub Node: C(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-38.7116	-75.0565	-216.398	-330.166	58	7	6	8009	2	27	16
C-D	-44.9114	-75.0691	-207.618	-327.5985	58	6	6	7955	2	30	16
C-E	-9.0214	0.0	-4.606	-13.6273	12	1	0	224	2	5	8
C-F	0.0	0.0	-27.6271	-27.6271	18	3	0	1238	0	6	7
C-I	0.0	0.0	-0.0898	-0.0898	4	0	0	35	0	0	0
C-J	-18.2994	2.081	-112.189	-128.4075	40	9	1	4026	0	13	5
D-E	0.0	0.0	-0.011	-0.011	2	0	0	4	0	0	0
D-F	-8.1929	6.3141	-28.6374	-30.5163	24	3	0	1178	0	6	8
E-F	-39.567	-22.2957	-155.207	-217.0697	52	7	5	6391	0	23	16
E-G	0.0	0.0	-1.0276	-1.0276	8	0	0	123	0	1	4
E-H	0.0	0.0	-0.7245	-0.7245	10	0	0	131	0	2	1
G-H	-49.1021	-53.5517	-163.664	-266.3178	57	12	5	6785	2	30	16
G-I	0.0	0.0	-0.1079	-0.1079	4	0	0	45	0	0	0
H-I	-20.4741	3.576	-114.155	-131.0531	41	10	1	3909	0	10	5
I-J	-34.9311	-50.6094	-164.209	-249.7495	53	8	5	6626	1	23	14
I-K	0.0	-25.8905	-123.213	-149.1035	46	5	0	4039	0	39	35
I-L	0.0	5.9858	-5.3825	0.6033	13	2	0	357	0	2	10
J-K	0.0	9.3913	-4.1832	5.2081	14	4	0	365	0	1	10
J-L	-15.3814	-7.3795	-49.7085	-72.4693	32	2	0	2212	0	10	4
K-L	-42.1809	-24.3047	-143.709	-210.1946	50	7	5	6269	0	21	14

Interface residues

• A-B: ALA46B, ALA58A, ALA68A, ALA70A, ARG42B, ARG47A, ARG60A, ARG63A, ARG72B, ASN60B, ASP54A, GLN2B, GLN40B, GLN48A, GLN49B, GLN50A, GLN52A, GLN62A, GLN62B, GLU53A, GLU56A, GLU59A, GLU64A, GLU64B, GLU65A, GLU66A, GLU67A, GLY10B, GLY47B, HIS68B, ILE3B, ILE44B, ILE51A, ILE61B, LEU43B, LEU50B, LEU57A, LEU61A, LEU67B, LEU69B, LEU71B, LEU73B, LEU8B, LYS11B, LYS48B, LYS49A, LYS63B, LYS6B, PHE45B, PHE4B, PHE69A, SER65B, THR66B, THR7B, THR9B, TRP55A, TYR43A, VAL70B
• C-D: ALA46D, ALA58C, ALA68C, ALA70C, ARG42D, ARG47C, ARG60C, ARG63C, ARG72D, ASN60D, ASP54C, GLN40D, GLN48C, GLN49D, GLN50C, GLN52C, GLN62C, GLN62D, GLU53C, GLU56C, GLU59C, GLU64C, GLU64D, GLU65C, GLU66C, GLU67C, GLY10D, GLY47D, HIS68D, ILE44D, ILE51C, ILE61D, LEU43D, LEU50D, LEU57C, LEU61C, LEU67D, LEU69D, LEU71D, LEU73D, LEU8D, LYS11D, LYS48D, LYS49C, LYS63D, LYS6D, PHE45D, PHE4D, PHE69C, SER65D, SER72C, THR66D, THR7D, THR9D, TRP39C, TRP55C, TYR43C, VAL70D
• C-E: ALA58E, ARG60C, ARG60E, ARG63E, GLN62E, GLU53C, GLU56C, GLU59E, GLU67C, LEU57C, LYS49C, TRP55E
• C-F: ALA58C, ARG60C, ARG63C, GLN62C, GLU56C, GLU64C, GLU65C, GLU67C, GLY10F, ILE36F, LEU57C, LEU61C, LEU71F, LEU73F, LEU8F, LYS11F, THR7F, THR9F
• C-I: ALA30I, GLN32I, LEU17C, PRO29I
• C-J: ALA30C, ALA46J, ARG40C, ARG54J, ASN28C, ASN60J, ASP21J, ASP52J, ASP58J, CYS19C, CYS23C, CYS35C, CYS38C, GLN49J, GLU18J, GLU51J, GLY24C, GLY27C, GLY53J, ILE61J, LEU17C, LEU18C, LEU50J, LEU56J, LYS37C, LYS48J, PHE34C, PHE45J, PRO19J, PRO29C, SER20J, SER36C, SER57J, THR22J, THR55J, TRP31C, TRP39C, TYR25C, TYR26C, TYR59J
• D-E: GLY47D, TRP55E
• D-F: ALA46D, ARG42D, ARG54D, ARG72D, GLN49D, GLU34F, GLU51D, GLY10F, GLY47D, ILE13F, ILE44D, LEU43D, LEU50D, LEU8F, LYS11F, LYS48D, LYS6F, PHE45D, PHE4F, THR12F, THR14F, THR7F, THR9F, TYR59D
• E-F: ALA46F, ALA58E, ARG42F, ARG47E, ARG60E, ARG63E, ARG72F, ASN60F, ASP54E, GLN2F, GLN32E, GLN48E, GLN49F, GLN50E, GLN52E, GLN62E, GLN62F, GLU53E, GLU56E, GLU59E, GLU64E, GLU64F, GLY10F, GLY47F, HIS68F, ILE3F, ILE44F, ILE51E, ILE61F, LEU43F, LEU50F, LEU57E, LEU61E, LEU67F, LEU69F, LEU71F, LEU73F, LEU8F, LYS48F, LYS49E, LYS63F, LYS6F, PHE45F, PHE4F, SER65F, THR66F, THR7F, THR9F, TRP39E, TRP55E, TYR43E, VAL70F
• E-G: ARG40G, CYS23E, GLN48G, GLY22E, GLY24E, HIS44G, LEU18E, LYS21E
• E-H: CYS23E, GLN2H, GLU64H, GLY24E, LYS37E, LYS6H, PHE4H, THR12H, THR14H, TYR25E
• G-H: ALA46H, ALA58G, ALA68G, ARG42H, ARG47G, ARG60G, ARG63G, ARG72H, ASN60H, ASP54G, GLN2H, GLN40H, GLN48G, GLN49H, GLN50G, GLN52G, GLN62G, GLN62H, GLU53G, GLU56G, GLU59G, GLU64G, GLU64H, GLU65G, GLU66G, GLY10H, GLY47H, HIS44G, HIS68H, ILE3H, ILE44H, ILE51G, ILE61H, LEU43H, LEU50H, LEU57G, LEU61G, LEU67H, LEU69H, LEU71H, LEU8H, LYS48H, LYS49G, LYS63H, LYS6H, MET1H, PHE45H, PHE4H, PHE69G, SER65H, THR66H, THR7H, THR9H, TRP39G, TRP55G, TYR43G, VAL70H
• G-I: ALA30G, GLN32G, LEU17I, PRO29G
• H-I: ALA30I, ALA46H, ARG40I, ARG54H, ASN28I, ASN60H, ASP21H, ASP58H, CYS19I, CYS23I, CYS35I, CYS38I, GLN49H, GLN62H, GLU18H, GLU51H, GLY24I, GLY27I, GLY53H, ILE23H, ILE61H, LEU17I, LEU18I, LEU50H, LEU56H, LYS37I, LYS48H, PHE34I, PHE45H, PRO19H, PRO29I, SER20H, SER36I, SER57H, THR22H, THR55H, TRP31I, TRP39I, TYR25I, TYR26I, TYR59H
• I-J: ALA46J, ALA58I, ALA68I, ARG42J, ARG47I, ARG60I, ARG63I, ASN60J, ASP54I, GLN2J, GLN40J, GLN48I, GLN49J, GLN50I, GLN52I, GLN62I, GLN62J, GLU53I, GLU56I, GLU59I, GLU64I, GLU64J, GLU65I, GLU66I, GLY10J, GLY47J, HIS68J, ILE3J, ILE44J, ILE51I, ILE61J, LEU43J, LEU57I, LEU61I, LEU67J, LEU69J, LEU71J, LEU8J, LYS11J, LYS48J, LYS49I, LYS63J, LYS6J, PHE45J, PHE4J, SER65J, THR66J, THR7J, THR9J, TRP39I, TRP55I, TYR43I, VAL70J
• I-K: ALA46I, ALA46K, ARG40I, ARG40K, ARG47I, ARG47K, ARG63I, ARG63K, ASP54I, ASP54K, CYS38I, GLN48I, GLN48K, GLN50I, GLN50K, GLN52I, GLN52K, GLN62I, GLN62K, GLU41I, GLU41K, GLU42I, GLU42K, GLU53I, GLU53K, GLU56I, GLU56K, GLU59I, GLU59K, GLU66I, HIS44I, HIS44K, ILE51I, ILE51K, LYS37I, LYS37K, LYS45I, LYS45K, LYS49I, LYS49K, TRP39I, TRP39K, TRP55I, TRP55K, TYR43I, TYR43K
• I-L: ARG40I, ARG47I, GLN48I, GLY10L, HIS44I, HIS68L, LEU8L, LYS11L, LYS6L, THR12L, THR66L, THR9L, TYR43I
• J-K: ARG40K, ARG47K, GLN48K, GLY10J, HIS44K, HIS68J, LEU8J, LYS11J, LYS6J, THR12J, THR66J, THR7J, THR9J, TYR43K
• J-L: GLN2J, GLN2L, GLU64J, GLU64L, GLY10J, GLY10L, ILE13J, ILE13L, ILE3J, ILE3L, LYS11J, LYS11L, LYS33J, LYS33L, LYS63J, LYS63L, LYS6J, LYS6L, PHE4J, PHE4L, THR12J, THR12L, THR14J, THR14L, THR66J, THR66L, THR7J, THR7L, THR9J, THR9L, VAL5J, VAL5L
• K-L: ALA46L, ALA58K, ARG42L, ARG47K, ARG60K, ARG63K, ARG72L, ASN60L, ASP54K, GLN32K, GLN48K, GLN49L, GLN50K, GLN52K, GLN62K, GLN62L, GLU53K, GLU56K, GLU59K, GLU64K, GLU64L, GLY10L, GLY47L, HIS68L, ILE3L, ILE44L, ILE51K, ILE61L, LEU43L, LEU50L, LEU57K, LEU61K, LEU67L, LEU69L, LEU71L, LEU73L, LEU8L, LYS48L, LYS63L, LYS6L, PHE45L, PHE4L, SER65L, THR66L, THR7L, THR9L, TRP39K, TRP55K, TYR43K, VAL70L