2C7E

revised atomic structure fitting into a groel(d398a)-atp7 cryo-em map (emd 1047)

• Total interactions analyzed: 91
• Total true interactions: 25
• Strongest Interaction:
  • Chains: L-M
  • Int. Res.: 130
  • Norm. En. per Res.: -1.0897
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-25.2181	-4.1504	170.871	141.5025	131	78	2	10531	0	49	62
A-G	-25.2233	-4.1524	170.826	141.4503	131	78	2	10530	0	49	62
A-H	0.0	0.0	-2.4972	-2.4972	10	0	0	311	0	3	1
B-C	-25.2209	-4.1512	171.166	141.794	131	78	2	10530	0	49	62
B-H	0.0	0.0	-2.4932	-2.4932	12	0	2	283	0	3	3
B-I	0.0	0.0	-2.4976	-2.4976	10	0	0	311	0	3	1
C-D	-25.2085	-4.1501	170.887	141.5284	131	78	2	10530	0	49	62
C-I	0.0	0.0	-2.4922	-2.4922	12	0	2	283	0	3	3
C-J	0.0	0.0	-2.4971	-2.4971	10	0	0	311	0	3	1
D-E	-25.2165	-4.1515	171.126	141.758	131	78	2	10529	0	49	62
D-J	0.0	0.0	-2.4925	-2.4925	12	0	2	283	0	3	3
D-K	0.0	0.0	-2.4971	-2.4971	10	0	0	311	0	3	1
E-F	-25.2063	-4.1505	170.751	141.3942	131	78	2	10532	0	49	62
E-K	0.0	0.0	-2.4924	-2.4924	12	0	2	283	0	3	3
E-L	0.0	0.0	-2.4973	-2.4973	10	0	0	311	0	3	1
F-G	-25.2269	-4.1482	170.723	141.348	131	78	2	10531	0	49	62
F-L	0.0	0.0	-2.4935	-2.4935	12	0	2	283	0	3	3
G-M	0.0	0.0	-2.4928	-2.4928	12	0	2	283	0	0	1
H-I	-10.7892	-27.83	-104.815	-143.4342	138	33	3	9453	0	53	58
H-N	-10.7919	-27.8328			22
I-J	-10.7932	-27.8301	-104.818	-143.4414	138	33	3	9453	0	53	58
J-K	-10.7889	-27.8264	-104.877	-143.4923	138	33	3	9454	0	53	58
K-L	-10.782	-27.8316	-104.935	-143.5485	138	33	3	9454	0	53	58
L-M	-10.7854	-27.828	-103.045	-141.6585	130	33	3	9303	0	52	53
M-N	-10.7813	-27.8292			22

Interface residues

• A-B: ALA12B, ALA243A, ALA260B, ALA26A, ALA2B, ALA3B, ALA46A, ALA481A, ALA511B, ALA71B, ALA84B, ARG118B, ARG18A, ARG231B, ARG322A, ARG36A, ARG501B, ARG58A, ASN112B, ASN153A, ASN21A, ASN229B, ASN37A, ASN433B, ASN457A, ASN68A, ASN68B, ASP115B, ASP25A, ASP41A, ASP523B, ASP5B, ASP64A, ASP83B, CYS458A, CYS519B, GLN319A, GLN432B, GLN436B, GLN505B, GLN72B, GLU216A, GLU257B, GLU386A, GLU388A, GLU391A, GLU460A, GLU483A, GLU518B, GLU59A, GLU61A, GLU61B, GLU63A, GLU76B, GLY244A, GLY256B, GLY32A, GLY35A, GLY459A, GLY45A, GLY512B, GLY70B, GLY9B, ILE230B, ILE49A, ILE515B, ILE60A, LEU23A, LEU40A, LEU513B, LEU524B, LEU62A, LYS117B, LYS245A, LYS277B, LYS321A, LYS327B, LYS34A, LYS42A, LYS4B, LYS51A, LYS526B, LYS65B, LYS75B, LYS7B, LYS80B, MET111B, MET114B, MET16B, MET514B, MET520B, MET69B, MET73B, PHE219A, PHE44A, PHE66B, PHE8B, PRO113B, PRO218A, PRO33A, PRO47A, SER217A, SER228B, SER43A, SER509B, SER79B, THR181A, THR261B, THR30A, THR385A, THR482A, THR48A, THR50A, THR516B, THR517B, THR522B, TYR506B, VAL107B, VAL22A, VAL27A, VAL29A, VAL336A, VAL387A, VAL38A, VAL39A, VAL510B, VAL521B, VAL56A, VAL6B, VAL74B, VAL77B
• A-G: ALA12A, ALA243G, ALA260A, ALA26G, ALA2A, ALA3A, ALA46G, ALA481G, ALA511A, ALA71A, ALA84A, ARG118A, ARG18G, ARG231A, ARG322G, ARG36G, ARG501A, ARG58G, ASN112A, ASN153G, ASN21G, ASN229A, ASN37G, ASN433A, ASN457G, ASN68A, ASN68G, ASP115A, ASP25G, ASP41G, ASP523A, ASP5A, ASP64G, ASP83A, CYS458G, CYS519A, GLN319G, GLN432A, GLN436A, GLN505A, GLN72A, GLU216G, GLU257A, GLU386G, GLU388G, GLU391G, GLU460G, GLU483G, GLU518A, GLU59G, GLU61A, GLU61G, GLU63G, GLU76A, GLY244G, GLY256A, GLY32G, GLY35G, GLY459G, GLY45G, GLY512A, GLY70A, GLY9A, ILE230A, ILE49G, ILE515A, ILE60G, LEU23G, LEU40G, LEU513A, LEU524A, LEU62G, LYS117A, LYS245G, LYS277A, LYS321G, LYS327A, LYS34G, LYS42G, LYS4A, LYS51G, LYS526A, LYS65A, LYS75A, LYS7A, LYS80A, MET111A, MET114A, MET16A, MET514A, MET520A, MET69A, MET73A, PHE219G, PHE44G, PHE66A, PHE8A, PRO113A, PRO218G, PRO33G, PRO47G, SER217G, SER228A, SER43G, SER509A, SER79A, THR181G, THR261A, THR30G, THR385G, THR482G, THR48G, THR50G, THR516A, THR517A, THR522A, TYR506A, VAL107A, VAL22G, VAL27G, VAL29G, VAL336G, VAL387G, VAL38G, VAL39G, VAL510A, VAL521A, VAL56G, VAL6A, VAL74A, VAL77A
• A-H: ARG452A, ARG452H, ASN467A, ASN467H, GLU461A, GLU461H, SER463A, SER463H, VAL464A, VAL464H
• B-C: ALA12C, ALA243B, ALA260C, ALA26B, ALA2C, ALA3C, ALA46B, ALA481B, ALA511C, ALA71C, ALA84C, ARG118C, ARG18B, ARG231C, ARG322B, ARG36B, ARG501C, ARG58B, ASN112C, ASN153B, ASN21B, ASN229C, ASN37B, ASN433C, ASN457B, ASN68B, ASN68C, ASP115C, ASP25B, ASP41B, ASP523C, ASP5C, ASP64B, ASP83C, CYS458B, CYS519C, GLN319B, GLN432C, GLN436C, GLN505C, GLN72C, GLU216B, GLU257C, GLU386B, GLU388B, GLU391B, GLU460B, GLU483B, GLU518C, GLU59B, GLU61B, GLU61C, GLU63B, GLU76C, GLY244B, GLY256C, GLY32B, GLY35B, GLY459B, GLY45B, GLY512C, GLY70C, GLY9C, ILE230C, ILE49B, ILE515C, ILE60B, LEU23B, LEU40B, LEU513C, LEU524C, LEU62B, LYS117C, LYS245B, LYS277C, LYS321B, LYS327C, LYS34B, LYS42B, LYS4C, LYS51B, LYS526C, LYS65C, LYS75C, LYS7C, LYS80C, MET111C, MET114C, MET16C, MET514C, MET520C, MET69C, MET73C, PHE219B, PHE44B, PHE66C, PHE8C, PRO113C, PRO218B, PRO33B, PRO47B, SER217B, SER228C, SER43B, SER509C, SER79C, THR181B, THR261C, THR30B, THR385B, THR482B, THR48B, THR50B, THR516C, THR517C, THR522C, TYR506C, VAL107C, VAL22B, VAL27B, VAL29B, VAL336B, VAL387B, VAL38B, VAL39B, VAL510C, VAL521C, VAL56B, VAL6C, VAL74C, VAL77C
• B-H: ALA106B, ALA106H, ALA108B, ALA108H, ALA109B, ALA109H, GLY110B, GLY110H, LYS105B, LYS105H, MET111B, MET111H
• B-I: ARG452B, ARG452I, ASN467B, ASN467I, GLU461B, GLU461I, SER463B, SER463I, VAL464B, VAL464I
• C-D: ALA12D, ALA243C, ALA260D, ALA26C, ALA2D, ALA3D, ALA46C, ALA481C, ALA511D, ALA71D, ALA84D, ARG118D, ARG18C, ARG231D, ARG322C, ARG36C, ARG501D, ARG58C, ASN112D, ASN153C, ASN21C, ASN229D, ASN37C, ASN433D, ASN457C, ASN68C, ASN68D, ASP115D, ASP25C, ASP41C, ASP523D, ASP5D, ASP64C, ASP83D, CYS458C, CYS519D, GLN319C, GLN432D, GLN436D, GLN505D, GLN72D, GLU216C, GLU257D, GLU386C, GLU388C, GLU391C, GLU460C, GLU483C, GLU518D, GLU59C, GLU61C, GLU61D, GLU63C, GLU76D, GLY244C, GLY256D, GLY32C, GLY35C, GLY459C, GLY45C, GLY512D, GLY70D, GLY9D, ILE230D, ILE49C, ILE515D, ILE60C, LEU23C, LEU40C, LEU513D, LEU524D, LEU62C, LYS117D, LYS245C, LYS277D, LYS321C, LYS327D, LYS34C, LYS42C, LYS4D, LYS51C, LYS526D, LYS65D, LYS75D, LYS7D, LYS80D, MET111D, MET114D, MET16D, MET514D, MET520D, MET69D, MET73D, PHE219C, PHE44C, PHE66D, PHE8D, PRO113D, PRO218C, PRO33C, PRO47C, SER217C, SER228D, SER43C, SER509D, SER79D, THR181C, THR261D, THR30C, THR385C, THR482C, THR48C, THR50C, THR516D, THR517D, THR522D, TYR506D, VAL107D, VAL22C, VAL27C, VAL29C, VAL336C, VAL387C, VAL38C, VAL39C, VAL510D, VAL521D, VAL56C, VAL6D, VAL74D, VAL77D
• C-I: ALA106C, ALA106I, ALA108C, ALA108I, ALA109C, ALA109I, GLY110C, GLY110I, LYS105C, LYS105I, MET111C, MET111I
• C-J: ARG452C, ARG452J, ASN467C, ASN467J, GLU461C, GLU461J, SER463C, SER463J, VAL464C, VAL464J
• D-E: ALA12E, ALA243D, ALA260E, ALA26D, ALA2E, ALA3E, ALA46D, ALA481D, ALA511E, ALA71E, ALA84E, ARG118E, ARG18D, ARG231E, ARG322D, ARG36D, ARG501E, ARG58D, ASN112E, ASN153D, ASN21D, ASN229E, ASN37D, ASN433E, ASN457D, ASN68D, ASN68E, ASP115E, ASP25D, ASP41D, ASP523E, ASP5E, ASP64D, ASP83E, CYS458D, CYS519E, GLN319D, GLN432E, GLN436E, GLN505E, GLN72E, GLU216D, GLU257E, GLU386D, GLU388D, GLU391D, GLU460D, GLU483D, GLU518E, GLU59D, GLU61D, GLU61E, GLU63D, GLU76E, GLY244D, GLY256E, GLY32D, GLY35D, GLY459D, GLY45D, GLY512E, GLY70E, GLY9E, ILE230E, ILE49D, ILE515E, ILE60D, LEU23D, LEU40D, LEU513E, LEU524E, LEU62D, LYS117E, LYS245D, LYS277E, LYS321D, LYS327E, LYS34D, LYS42D, LYS4E, LYS51D, LYS526E, LYS65E, LYS75E, LYS7E, LYS80E, MET111E, MET114E, MET16E, MET514E, MET520E, MET69E, MET73E, PHE219D, PHE44D, PHE66E, PHE8E, PRO113E, PRO218D, PRO33D, PRO47D, SER217D, SER228E, SER43D, SER509E, SER79E, THR181D, THR261E, THR30D, THR385D, THR482D, THR48D, THR50D, THR516E, THR517E, THR522E, TYR506E, VAL107E, VAL22D, VAL27D, VAL29D, VAL336D, VAL387D, VAL38D, VAL39D, VAL510E, VAL521E, VAL56D, VAL6E, VAL74E, VAL77E
• D-J: ALA106D, ALA106J, ALA108D, ALA108J, ALA109D, ALA109J, GLY110D, GLY110J, LYS105D, LYS105J, MET111D, MET111J
• D-K: ARG452D, ARG452K, ASN467D, ASN467K, GLU461D, GLU461K, SER463D, SER463K, VAL464D, VAL464K
• E-F: ALA12F, ALA243E, ALA260F, ALA26E, ALA2F, ALA3F, ALA46E, ALA481E, ALA511F, ALA71F, ALA84F, ARG118F, ARG18E, ARG231F, ARG322E, ARG36E, ARG501F, ARG58E, ASN112F, ASN153E, ASN21E, ASN229F, ASN37E, ASN433F, ASN457E, ASN68E, ASN68F, ASP115F, ASP25E, ASP41E, ASP523F, ASP5F, ASP64E, ASP83F, CYS458E, CYS519F, GLN319E, GLN432F, GLN436F, GLN505F, GLN72F, GLU216E, GLU257F, GLU386E, GLU388E, GLU391E, GLU460E, GLU483E, GLU518F, GLU59E, GLU61E, GLU61F, GLU63E, GLU76F, GLY244E, GLY256F, GLY32E, GLY35E, GLY459E, GLY45E, GLY512F, GLY70F, GLY9F, ILE230F, ILE49E, ILE515F, ILE60E, LEU23E, LEU40E, LEU513F, LEU524F, LEU62E, LYS117F, LYS245E, LYS277F, LYS321E, LYS327F, LYS34E, LYS42E, LYS4F, LYS51E, LYS526F, LYS65F, LYS75F, LYS7F, LYS80F, MET111F, MET114F, MET16F, MET514F, MET520F, MET69F, MET73F, PHE219E, PHE44E, PHE66F, PHE8F, PRO113F, PRO218E, PRO33E, PRO47E, SER217E, SER228F, SER43E, SER509F, SER79F, THR181E, THR261F, THR30E, THR385E, THR482E, THR48E, THR50E, THR516F, THR517F, THR522F, TYR506F, VAL107F, VAL22E, VAL27E, VAL29E, VAL336E, VAL387E, VAL38E, VAL39E, VAL510F, VAL521F, VAL56E, VAL6F, VAL74F, VAL77F
• E-K: ALA106E, ALA106K, ALA108E, ALA108K, ALA109E, ALA109K, GLY110E, GLY110K, LYS105E, LYS105K, MET111E, MET111K
• E-L: ARG452E, ARG452L, ASN467E, ASN467L, GLU461E, GLU461L, SER463E, SER463L, VAL464E, VAL464L
• F-G: ALA12G, ALA243F, ALA260G, ALA26F, ALA2G, ALA3G, ALA46F, ALA481F, ALA511G, ALA71G, ALA84G, ARG118G, ARG18F, ARG231G, ARG322F, ARG36F, ARG501G, ARG58F, ASN112G, ASN153F, ASN21F, ASN229G, ASN37F, ASN433G, ASN457F, ASN68F, ASN68G, ASP115G, ASP25F, ASP41F, ASP523G, ASP5G, ASP64F, ASP83G, CYS458F, CYS519G, GLN319F, GLN432G, GLN436G, GLN505G, GLN72G, GLU216F, GLU257G, GLU386F, GLU388F, GLU391F, GLU460F, GLU483F, GLU518G, GLU59F, GLU61F, GLU61G, GLU63F, GLU76G, GLY244F, GLY256G, GLY32F, GLY35F, GLY459F, GLY45F, GLY512G, GLY70G, GLY9G, ILE230G, ILE49F, ILE515G, ILE60F, LEU23F, LEU40F, LEU513G, LEU524G, LEU62F, LYS117G, LYS245F, LYS277G, LYS321F, LYS327G, LYS34F, LYS42F, LYS4G, LYS51F, LYS526G, LYS65G, LYS75G, LYS7G, LYS80G, MET111G, MET114G, MET16G, MET514G, MET520G, MET69G, MET73G, PHE219F, PHE44F, PHE66G, PHE8G, PRO113G, PRO218F, PRO33F, PRO47F, SER217F, SER228G, SER43F, SER509G, SER79G, THR181F, THR261G, THR30F, THR385F, THR482F, THR48F, THR50F, THR516G, THR517G, THR522G, TYR506G, VAL107G, VAL22F, VAL27F, VAL29F, VAL336F, VAL387F, VAL38F, VAL39F, VAL510G, VAL521G, VAL56F, VAL6G, VAL74G, VAL77G
• F-L: ALA106F, ALA106L, ALA108F, ALA108L, ALA109F, ALA109L, GLY110F, GLY110L, LYS105F, LYS105L, MET111F, MET111L
• G-M: ALA106G, ALA106M, ALA108G, ALA108M, ALA109G, ALA109M, GLY110G, GLY110M, LYS105G, LYS105M, MET111G, MET111M
• H-I: ALA12H, ALA241I, ALA243I, ALA26I, ALA2H, ALA383I, ALA384I, ALA3H, ALA46I, ALA481I, ALA71H, ARG118H, ARG18I, ARG197H, ARG231H, ARG284H, ARG285H, ARG36I, ARG58I, ASN112H, ASN21I, ASN229H, ASN37I, ASN433H, ASN457I, ASN68H, ASN68I, ASP115H, ASP179I, ASP25I, ASP283H, ASP41I, ASP523H, ASP5H, ASP64I, CYS458I, CYS519H, GLN184I, GLN432H, GLN436H, GLN72H, GLU216I, GLU232H, GLU238I, GLU252H, GLU255H, GLU257H, GLU386I, GLU460I, GLU483I, GLU518H, GLU59I, GLU61I, GLU63I, GLU76H, GLY180I, GLY182I, GLY244I, GLY269I, GLY282H, GLY32I, GLY35I, GLY459I, GLY45I, GLY512H, GLY70H, GLY9H, ILE49I, ILE515H, ILE60I, LEU183I, LEU23I, LEU40I, LEU456I, LEU513H, LEU524H, LEU62I, LYS117H, LYS226H, LYS242I, LYS245I, LYS272I, LYS277H, LYS34I, LYS390I, LYS42I, LYS4H, LYS51I, LYS526H, LYS65H, LYS75H, LYS7H, LYS80H, MET111H, MET114H, MET16H, MET389I, MET514H, MET520H, MET69H, MET73H, PHE281H, PHE44I, PHE66H, PHE8H, PRO113H, PRO246I, PRO33I, PRO47I, PRO525H, SER228H, SER43I, SER509H, SER79H, THR181I, THR30I, THR385I, THR482I, THR48I, THR50I, THR516H, THR517H, THR522H, TYR360H, VAL107H, VAL22I, VAL240I, VAL271I, VAL27I, VAL29I, VAL38I, VAL39I, VAL510H, VAL521H, VAL56I, VAL6H, VAL74H, VAL77H
• H-N: ARG231N, ARG36H, ASP41H, ASP523N, ASP5N, CYS519N, GLU216H, GLU257N, GLU386H, GLU518N, GLU59H, GLU61H, GLU63H, LYS226N, LYS242H, LYS272H, LYS277N, LYS4N, LYS526N, LYS65N, THR522N, VAL39H
• I-J: ALA12I, ALA241J, ALA243J, ALA26J, ALA2I, ALA383J, ALA384J, ALA3I, ALA46J, ALA481J, ALA71I, ARG118I, ARG18J, ARG197I, ARG231I, ARG284I, ARG285I, ARG36J, ARG58J, ASN112I, ASN21J, ASN229I, ASN37J, ASN433I, ASN457J, ASN68I, ASN68J, ASP115I, ASP179J, ASP25J, ASP283I, ASP41J, ASP523I, ASP5I, ASP64J, CYS458J, CYS519I, GLN184J, GLN432I, GLN436I, GLN72I, GLU216J, GLU232I, GLU238J, GLU252I, GLU255I, GLU257I, GLU386J, GLU460J, GLU483J, GLU518I, GLU59J, GLU61J, GLU63J, GLU76I, GLY180J, GLY182J, GLY244J, GLY269J, GLY282I, GLY32J, GLY35J, GLY459J, GLY45J, GLY512I, GLY70I, GLY9I, ILE49J, ILE515I, ILE60J, LEU183J, LEU23J, LEU40J, LEU456J, LEU513I, LEU524I, LEU62J, LYS117I, LYS226I, LYS242J, LYS245J, LYS272J, LYS277I, LYS34J, LYS390J, LYS42J, LYS4I, LYS51J, LYS526I, LYS65I, LYS75I, LYS7I, LYS80I, MET111I, MET114I, MET16I, MET389J, MET514I, MET520I, MET69I, MET73I, PHE281I, PHE44J, PHE66I, PHE8I, PRO113I, PRO246J, PRO33J, PRO47J, PRO525I, SER228I, SER43J, SER509I, SER79I, THR181J, THR30J, THR385J, THR482J, THR48J, THR50J, THR516I, THR517I, THR522I, TYR360I, VAL107I, VAL22J, VAL240J, VAL271J, VAL27J, VAL29J, VAL38J, VAL39J, VAL510I, VAL521I, VAL56J, VAL6I, VAL74I, VAL77I
• J-K: ALA12J, ALA241K, ALA243K, ALA26K, ALA2J, ALA383K, ALA384K, ALA3J, ALA46K, ALA481K, ALA71J, ARG118J, ARG18K, ARG197J, ARG231J, ARG284J, ARG285J, ARG36K, ARG58K, ASN112J, ASN21K, ASN229J, ASN37K, ASN433J, ASN457K, ASN68J, ASN68K, ASP115J, ASP179K, ASP25K, ASP283J, ASP41K, ASP523J, ASP5J, ASP64K, CYS458K, CYS519J, GLN184K, GLN432J, GLN436J, GLN72J, GLU216K, GLU232J, GLU238K, GLU252J, GLU255J, GLU257J, GLU386K, GLU460K, GLU483K, GLU518J, GLU59K, GLU61K, GLU63K, GLU76J, GLY180K, GLY182K, GLY244K, GLY269K, GLY282J, GLY32K, GLY35K, GLY459K, GLY45K, GLY512J, GLY70J, GLY9J, ILE49K, ILE515J, ILE60K, LEU183K, LEU23K, LEU40K, LEU456K, LEU513J, LEU524J, LEU62K, LYS117J, LYS226J, LYS242K, LYS245K, LYS272K, LYS277J, LYS34K, LYS390K, LYS42K, LYS4J, LYS51K, LYS526J, LYS65J, LYS75J, LYS7J, LYS80J, MET111J, MET114J, MET16J, MET389K, MET514J, MET520J, MET69J, MET73J, PHE281J, PHE44K, PHE66J, PHE8J, PRO113J, PRO246K, PRO33K, PRO47K, PRO525J, SER228J, SER43K, SER509J, SER79J, THR181K, THR30K, THR385K, THR482K, THR48K, THR50K, THR516J, THR517J, THR522J, TYR360J, VAL107J, VAL22K, VAL240K, VAL271K, VAL27K, VAL29K, VAL38K, VAL39K, VAL510J, VAL521J, VAL56K, VAL6J, VAL74J, VAL77J
• K-L: ALA12K, ALA241L, ALA243L, ALA26L, ALA2K, ALA383L, ALA384L, ALA3K, ALA46L, ALA481L, ALA71K, ARG118K, ARG18L, ARG197K, ARG231K, ARG284K, ARG285K, ARG36L, ARG58L, ASN112K, ASN21L, ASN229K, ASN37L, ASN433K, ASN457L, ASN68K, ASN68L, ASP115K, ASP179L, ASP25L, ASP283K, ASP41L, ASP523K, ASP5K, ASP64L, CYS458L, CYS519K, GLN184L, GLN432K, GLN436K, GLN72K, GLU216L, GLU232K, GLU238L, GLU252K, GLU255K, GLU257K, GLU386L, GLU460L, GLU483L, GLU518K, GLU59L, GLU61L, GLU63L, GLU76K, GLY180L, GLY182L, GLY244L, GLY269L, GLY282K, GLY32L, GLY35L, GLY459L, GLY45L, GLY512K, GLY70K, GLY9K, ILE49L, ILE515K, ILE60L, LEU183L, LEU23L, LEU40L, LEU456L, LEU513K, LEU524K, LEU62L, LYS117K, LYS226K, LYS242L, LYS245L, LYS272L, LYS277K, LYS34L, LYS390L, LYS42L, LYS4K, LYS51L, LYS526K, LYS65K, LYS75K, LYS7K, LYS80K, MET111K, MET114K, MET16K, MET389L, MET514K, MET520K, MET69K, MET73K, PHE281K, PHE44L, PHE66K, PHE8K, PRO113K, PRO246L, PRO33L, PRO47L, PRO525K, SER228K, SER43L, SER509K, SER79K, THR181L, THR30L, THR385L, THR482L, THR48L, THR50L, THR516K, THR517K, THR522K, TYR360K, VAL107K, VAL22L, VAL240L, VAL271L, VAL27L, VAL29L, VAL38L, VAL39L, VAL510K, VAL521K, VAL56L, VAL6K, VAL74K, VAL77K
• L-M: ALA12L, ALA241M, ALA243M, ALA26M, ALA2L, ALA383M, ALA384M, ALA3L, ALA46M, ALA71L, ARG118L, ARG18M, ARG197L, ARG231L, ARG284L, ARG285L, ARG36M, ARG58M, ASN112L, ASN21M, ASN229L, ASN37M, ASN433L, ASN68L, ASN68M, ASP115L, ASP179M, ASP25M, ASP283L, ASP41M, ASP523L, ASP5L, ASP64M, CYS519L, GLN184M, GLN432L, GLN436L, GLN72L, GLU216M, GLU232L, GLU238M, GLU252L, GLU255L, GLU257L, GLU386M, GLU518L, GLU59M, GLU61M, GLU63M, GLU76L, GLY180M, GLY182M, GLY244M, GLY269M, GLY282L, GLY32M, GLY35M, GLY45M, GLY512L, GLY70L, GLY9L, ILE49M, ILE515L, ILE60M, LEU183M, LEU23M, LEU40M, LEU513L, LEU524L, LEU62M, LYS117L, LYS226L, LYS242M, LYS245M, LYS272M, LYS277L, LYS34M, LYS390M, LYS42M, LYS4L, LYS51M, LYS526L, LYS65L, LYS75L, LYS7L, LYS80L, MET111L, MET114L, MET16L, MET389M, MET514L, MET520L, MET69L, MET73L, PHE281L, PHE44M, PHE66L, PHE8L, PRO113L, PRO246M, PRO33M, PRO47M, PRO525L, SER228L, SER43M, SER509L, SER79L, THR181M, THR30M, THR385M, THR48M, THR50M, THR516L, THR517L, THR522L, TYR360L, VAL107L, VAL22M, VAL240M, VAL271M, VAL27M, VAL29M, VAL38M, VAL39M, VAL510L, VAL521L, VAL56M, VAL6L, VAL74L, VAL77L
• M-N: ARG231M, ARG36N, ASP41N, ASP523M, ASP5M, CYS519M, GLU216N, GLU257M, GLU386N, GLU518M, GLU59N, GLU61N, GLU63N, LYS226M, LYS242N, LYS272N, LYS277M, LYS4M, LYS526M, LYS65M, THR522M, VAL39N