2C63

14-3-3 protein eta (human) complexed to peptide

• Total interactions analyzed: 28
• Total true interactions: 9
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 99
  • Norm. En. per Res.: -3.3099
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.7103	-44.4316	-232.033	-308.1749	97	5	12	10107	8	63	62
A-C	-22.1634	-11.2033	-70.6124	-103.9791	42	7	0	3251	2	21	23
A-D	0.0	0.0	-0.6447	-0.6447	3	0	0	68	0	1	3
A-P	-10.1724	0.0	-49.5937	-59.7661	37	1	2	2584	0	0	0
B-D	-27.3531	-9.6594	-81.2138	-118.2263	40	6	0	3398	3	18	21
B-Q	-9.9068	0.0	-48.6305	-58.5373	36	1	3	2557	0	0	0
C-D	-30.7884	-46.6784	-250.211	-327.6778	99	6	13	10524	8	64	66
C-R	-8.3986	0.0	-50.4875	-58.8861	36	1	3	2636	0	0	0
D-S	-24.3329	0.0	-49.463	-73.7959	34	2	3	2635	0	0	0

Interface residues

• A-B: ALA11A, ALA11B, ALA14A, ALA14B, ALA17A, ALA17B, ALA26A, ALA26B, ALA55A, ALA55B, ALA84A, ALA84B, ARG10A, ARG10B, ARG12A, ARG12B, ARG19A, ARG19B, ARG56A, ARG56B, ARG61A, ARG61B, ARG86A, ARG86B, ASN75A, ASN75B, ASP21A, ASP21B, ASP22A, ASP22B, ASP3A, GLN16A, GLN16B, GLN6A, GLN6B, GLN9A, GLN9B, GLU15A, GLU15B, GLU18A, GLU18B, GLU5A, GLU5B, GLU67A, GLU67B, GLU80A, GLU80B, GLU90A, GLU90B, GLU92A, GLU92B, ILE63A, ILE63B, ILE66A, ILE66B, ILE89A, ILE89B, LEU13A, LEU13B, LEU79A, LEU79B, LEU7A, LEU93A, LEU93B, LYS77A, LYS77B, LYS78A, LYS78B, LYS81A, LYS81B, LYS83A, LYS83B, LYS88A, LYS88B, MET23A, MET23B, SER25A, SER25B, SER58A, SER58B, SER59A, SER59B, SER64A, SER64B, SER65B, THR70A, THR70B, TRP60A, TRP60B, TYR20A, TYR20B, TYR85A, TYR85B, VAL62A, VAL62B, VAL82A, VAL82B
• A-C: ALA26C, ALA29A, ALA29C, ARG4A, ARG4C, ASN111A, ASN111C, ASN34A, ASN34C, ASN98C, ASP105A, ASP105C, ASP3A, ASP3C, GLN6A, GLU32A, GLU32C, GLU35A, GLU35C, LEU103A, LEU103C, LEU33A, LEU33C, LEU7A, LEU7C, LYS106A, LYS106C, LYS110A, LYS110C, LYS28A, LYS28C, MET27C, PHE107A, PHE107C, PRO36A, SER102A, SER102C, SER25C, THR31A, THR31C, VAL30A, VAL30C
• A-D: LYS88A, LYS91A, LYS91D
• A-P: ALA176A, ARG132A, ARG57A, ASN178A, ASN229A, ASN43A, ASN51A, ASP129A, ASP218A, ASP228A, GLU185A, GLY174A, ILE171A, ILE222A, ILE3P, LEU173A, LEU175A, LEU177A, LEU221A, LEU225A, LEU226A, LEU232A, LEU5P, LYS125A, LYS50A, PHE122A, PHE179A, PRO170A, PRO6P, SER180A, SER46A, TRP233A, TYR133A, TYR154A, TYR184A, VAL181A, VAL47A
• B-D: ALA26B, ALA29B, ALA29D, ARG4B, ARG4D, ASN111B, ASN111D, ASN34B, ASN34D, ASP105B, ASP105D, ASP3B, ASP3D, GLU32B, GLU32D, GLU35B, GLU35D, LEU103B, LEU103D, LEU108B, LEU33B, LEU33D, LEU7B, LEU7D, LYS106B, LYS106D, LYS110B, LYS110D, LYS28B, LYS28D, PHE107B, PHE107D, PRO36D, SER102B, SER102D, SER25B, THR31B, THR31D, VAL30B, VAL30D
• B-Q: ALA176B, ARG132B, ARG57B, ASN178B, ASN229B, ASN43B, ASN51B, ASP129B, ASP218B, ASP228B, GLU185B, GLY174B, ILE171B, ILE222B, ILE3Q, LEU173B, LEU175B, LEU177B, LEU221B, LEU225B, LEU226B, LEU232B, LEU5Q, LYS125B, LYS50B, PHE122B, PHE179B, PRO170B, PRO6Q, SER180B, SER46B, TRP233B, TYR133B, TYR184B, VAL181B, VAL47B
• C-D: ALA11C, ALA11D, ALA14C, ALA14D, ALA17C, ALA17D, ALA26C, ALA26D, ALA55C, ALA55D, ALA84C, ALA84D, ARG10C, ARG10D, ARG12C, ARG12D, ARG19C, ARG19D, ARG56C, ARG56D, ARG57C, ARG61C, ARG61D, ARG86C, ARG86D, ASN75C, ASN75D, ASP21C, ASP21D, ASP22C, ASP22D, GLN16C, GLN16D, GLN6C, GLN6D, GLN9C, GLN9D, GLU15C, GLU15D, GLU18C, GLU18D, GLU5C, GLU5D, GLU67C, GLU67D, GLU80D, GLU87C, GLU87D, GLU90C, GLU90D, GLU92C, GLU92D, ILE63C, ILE63D, ILE66C, ILE66D, ILE89C, ILE89D, LEU13C, LEU13D, LEU79C, LEU79D, LEU7C, LEU93C, LEU93D, LYS77C, LYS77D, LYS78C, LYS78D, LYS81C, LYS81D, LYS83C, LYS83D, LYS88C, LYS88D, MET23C, MET23D, SER25C, SER25D, SER58C, SER58D, SER59C, SER59D, SER64C, SER64D, SER65C, SER65D, THR70C, THR70D, TRP60C, TRP60D, TYR20C, TYR20D, TYR85C, TYR85D, VAL62C, VAL62D, VAL82C, VAL82D
• C-R: ARG132C, ARG57C, ASN178C, ASN229C, ASN43C, ASN51C, ASP129C, ASP218C, ASP228C, GLU185C, GLY174C, ILE171C, ILE222C, ILE3R, LEU173C, LEU175C, LEU177C, LEU221C, LEU225C, LEU226C, LEU232C, LEU5R, LYS125C, LYS50C, PHE122C, PHE179C, PRO170C, PRO6R, SER180C, SER46C, TRP233C, TYR133C, TYR154C, TYR184C, VAL181C, VAL47C
• D-S: ARG132D, ARG57D, ASN178D, ASN229D, ASN43D, ASN51D, ASP129D, ASP218D, ASP228D, GLU185D, GLY174D, ILE171D, ILE222D, ILE3S, LEU173D, LEU175D, LEU177D, LEU221D, LEU225D, LEU226D, LEU232D, LEU5S, LYS125D, LYS50D, PHE122D, PHE179D, PRO170D, PRO6S, SER180D, SER46D, TRP233D, TYR133D, VAL181D, VAL47D