2C5L

structure of plc epsilon ras association domain with hras

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 65
  • Norm. En. per Res.: -3.6677
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-56.3804	44.7702	-213.745	-225.3552	93	10	0	7696	1	39	40
A-C	-37.934	-31.0213	-169.444	-238.3993	65	6	4	6122	3	25	12
B-D	-32.2406	-24.5952	-160.754	-217.5899	67	8	2	6161	1	26	13

Interface residues

• A-B: ALA130A, ALA130B, ALA134A, ALA134B, ALA155A, ALA155B, ARG123A, ARG123B, ARG128A, ARG128B, ARG135A, ARG135B, ARG161A, ARG161B, ARG164A, ARG164B, ASP132A, ASP132B, ASP154A, ASP154B, ASP47A, ASP47B, CYS118A, CYS118B, CYS51A, CYS51B, GLN129A, GLN129B, GLN131A, GLN131B, GLN150A, GLN150B, GLN165A, GLN165B, GLU126A, GLU126B, GLU143A, GLU143B, GLU153A, GLU153B, GLU162A, GLU162B, GLU49A, GLU49B, GLY115A, GLY115B, GLY138A, GLY138B, GLY151A, GLY151B, GLY48A, GLY48B, HIS166A, HIS166B, ILE139A, ILE139B, ILE142A, ILE142B, ILE163A, ILE163B, ILE46A, ILE46B, ILE84A, ILE84B, LEU113A, LEU113B, LEU133A, LEU133B, PRO140A, PRO140B, SER127A, SER127B, SER136A, SER136B, THR144A, THR144B, THR158A, THR158B, THR2A, THR2B, TYR137A, TYR137B, TYR141A, TYR141B, TYR157A, TYR157B, TYR4A, TYR4B, VAL112A, VAL112B, VAL160A, VAL45A, VAL45B
• A-C: ALA2155C, ALA2172C, ALA59A, ARG2150C, ARG41A, ASP2143C, ASP30A, ASP33A, ASP38A, ASP54A, ASP57A, CYS2170C, GLN2140C, GLN2148C, GLN2167C, GLN25A, GLN43A, GLN61A, GLU2147C, GLU31A, GLU37A, GLU3A, GLU63A, HIS2142C, HIS27A, ILE2153C, ILE2178C, ILE21A, ILE24A, ILE36A, ILE55A, LEU2176C, LEU2179C, LEU52A, LEU53A, LEU56A, LYS2154C, LYS2171C, LYS2173C, LYS42A, LYS5A, MET67A, PHE2137C, PHE2138C, PHE28A, PRO2146C, PRO2149C, PRO34A, SER17A, SER2145C, SER2175C, SER2177C, SER39A, THR20A, THR2151C, THR35A, THR74A, TYR2174C, TYR40A, TYR64A, VAL2139C, VAL2141C, VAL2144C, VAL2152C, VAL29A
• B-D: ALA2155D, ALA2172D, ALA59B, ARG2150D, ARG41B, ASN26B, ASP2143D, ASP30B, ASP33B, ASP38B, ASP54B, ASP57B, CYS2170D, GLN2140D, GLN2148D, GLN2167D, GLN25B, GLN43B, GLN61B, GLN70B, GLU2147D, GLU31B, GLU37B, GLU3B, GLU63B, HIS2142D, HIS27B, ILE2153D, ILE2178D, ILE21B, ILE24B, ILE36B, ILE55B, LEU2176D, LEU2179D, LEU52B, LEU53B, LEU56B, LYS2154D, LYS2171D, LYS2173D, LYS42B, LYS5B, MET67B, PHE2137D, PHE2138D, PHE28B, PRO2146D, PRO2149D, PRO34B, SER17B, SER2145D, SER2175D, SER2177D, SER39B, THR20B, THR2151D, THR35B, THR74B, TYR2174D, TYR40B, TYR64B, VAL2139D, VAL2141D, VAL2144D, VAL2152D, VAL29B