2C4M

starch phosphorylase: structural studies explain oxyanion- dependent kinetic stability and regulatory control.

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 258
  • Norm. En. per Res.: -3.4516
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-109.8307	-29.6452	-751.04	-890.5159	258	29	5	28847	8	140	123
A-C	-22.8245	27.3255	-133.475	-128.9739	77	10	1	4493	0	27	34
A-D	-4.5647	22.8551	-98.814	-80.5236	61	4	0	3551	1	19	23
B-C	-26.0467	34.9455	-102.805	-93.9062	64	5	0	3759	0	21	24
B-D	0.0	11.8789	-4.3648	7.5141	6	1	0	280	0	4	4
C-D	-100.4658	-32.3784	-753.238	-886.0822	257	28	7	28881	8	143	120

Interface residues

• A-B: ALA10A, ALA10B, ALA173A, ALA173B, ALA18A, ALA18B, ALA19A, ALA19B, ALA20A, ALA20B, ALA221A, ALA224A, ALA224B, ALA230A, ALA230B, ALA24A, ALA24B, ALA27A, ALA27B, ALA39A, ALA39B, ALA45A, ALA45B, ALA564A, ALA564B, ARG141A, ARG141B, ARG146A, ARG146B, ARG162A, ARG162B, ARG171A, ARG171B, ARG172A, ARG172B, ARG17A, ARG17B, ARG187A, ARG187B, ARG226A, ARG226B, ARG234A, ARG234B, ARG236A, ARG236B, ARG242A, ARG242B, ARG257A, ARG257B, ARG259A, ARG259B, ARG30A, ARG30B, ARG38A, ARG38B, ARG43A, ARG43B, ARG50A, ARG50B, ARG52A, ARG52B, ASN223A, ASN223B, ASN247A, ASN247B, ASP159A, ASP159B, ASP175A, ASP175B, ASP192A, ASP192B, ASP218A, ASP218B, ASP220A, ASP220B, ASP229A, ASP229B, ASP239A, ASP239B, ASP248A, ASP248B, ASP25A, ASP25B, ASP29A, ASP29B, ASP46A, ASP46B, ASP47A, ASP47B, CYS241A, CYS241B, GLN154A, GLN154B, GLN176A, GLN176B, GLN225A, GLN225B, GLN260A, GLN260B, GLN41A, GLN41B, GLU156A, GLU156B, GLU163A, GLU163B, GLU164A, GLU164B, GLU165A, GLU165B, GLU212A, GLU212B, GLU215A, GLU215B, GLU216A, GLU216B, GLU233B, GLU235A, GLU235B, GLU252A, GLU252B, GLU42A, GLU42B, GLU49A, GLU49B, GLU53A, GLU53B, GLY13A, GLY13B, GLY143A, GLY143B, GLY21A, GLY21B, GLY253A, GLY253B, GLY35A, GLY35B, GLY566A, GLY566B, HIS15A, HIS15B, ILE104A, ILE104B, ILE170A, ILE170B, ILE189A, ILE189B, ILE231A, ILE231B, ILE232A, ILE232B, ILE240A, ILE240B, ILE44A, ILE44B, LEU11A, LEU11B, LEU144A, LEU144B, LEU244A, LEU244B, LEU256A, LEU256B, LEU26A, LEU26B, LYS157A, LYS157B, LYS210A, LYS210B, LYS254A, LYS254B, LYS255A, LYS255B, LYS31A, LYS31B, LYS562B, LYS571A, LYS571B, PHE142A, PHE142B, PHE145A, PHE145B, PHE168A, PHE168B, PHE217A, PHE217B, PHE222A, PHE222B, PHE227A, PHE227B, PRO158A, PRO158B, PRO160A, PRO160B, PRO167A, PRO167B, PRO190A, PRO190B, PRO194A, PRO194B, PRO213A, PRO213B, PRO23A, PRO23B, PRO246A, PRO246B, PRO565A, PRO565B, SER14A, SER14B, SER174A, SER174B, SER238A, SER238B, SER37A, SER37B, THR169A, THR169B, THR228A, THR228B, THR22A, THR22B, THR249A, THR249B, THR250A, THR250B, THR28A, THR28B, THR34A, THR34B, TRP161A, TRP161B, TRP214A, TRP214B, TRP48A, TRP48B, TYR166A, TYR166B, TYR191A, TYR191B, TYR219A, TYR219B, TYR245A, TYR245B, TYR251A, TYR251B, TYR567A, TYR567B, VAL12A, VAL12B, VAL155A, VAL155B, VAL16A, VAL16B, VAL203B, VAL243A, VAL243B, VAL40A, VAL40B
• A-C: ALA224A, ALA224C, ARG226A, ARG226C, ARG355A, ARG355C, ARG569A, ARG569C, ASN223A, ASN223C, ASP182A, ASP182C, ASP220A, ASP220C, ASP229A, ASP229C, ASP345A, ASP345C, ASP713A, ASP713C, GLN225A, GLN225C, GLN347A, GLN347C, GLN350A, GLN350C, GLN351A, GLN351C, GLN388A, GLN388C, GLU252A, GLU252C, GLU346A, GLU346C, GLU358A, GLU358C, GLY253A, GLY253C, GLY390A, GLY390C, GLY709A, GLY709C, HIS389A, HIS389C, HIS716A, HIS716C, HIS720A, HIS720C, ILE348A, ILE348C, ILE387A, ILE387C, LEU710C, LYS254A, LYS254C, LYS255A, LYS255C, PHE349A, PHE353C, THR249A, THR249C, THR250A, THR250C, THR391A, THR391C, TRP344A, TRP354A, TRP354C, TRP357A, TRP357C, TYR251A, TYR251C, TYR712A, TYR712C, VAL392A, VAL568A, VAL568C
• A-D: ARG226D, ARG569D, ASN247D, ASN706A, ASN706D, ASN707A, ASN707D, ASP248D, ASP345D, ASP699A, ASP705A, ASP705D, ASP713A, ASP713D, GLN347D, GLN351D, GLU151D, GLU252D, GLU677A, GLU683A, GLU686A, GLY253D, GLY566D, GLY709A, GLY709D, GLY721A, GLY723A, HIS716A, HIS716D, HIS720A, ILE348D, ILE719A, LEU710A, LEU710D, LYS254D, LYS255D, LYS571D, LYS575D, LYS680A, LYS692A, PHE153D, PHE711A, PHE711D, PRO565D, PRO681A, SER678A, SER708A, SER708D, SER717D, THR249D, THR250A, THR250D, THR687A, TYR251D, TYR679A, TYR682A, TYR685A, TYR712A, TYR712D, TYR722A, VAL568D
• B-C: ALA674C, ARG226B, ARG569B, ARG676C, ASN247B, ASN706B, ASN706C, ASN707B, ASN707C, ASP345B, ASP699C, ASP705B, ASP705C, ASP713B, ASP713C, GLN347B, GLN351B, GLU151B, GLU252B, GLU677C, GLU683C, GLU686C, GLY253B, GLY566B, GLY709B, GLY709C, GLY721C, GLY723C, HIS716B, HIS716C, HIS720C, ILE348B, ILE719C, LEU710B, LEU710C, LYS254B, LYS255B, LYS571B, LYS575B, LYS680C, LYS692C, LYS715C, LYS724C, PHE153B, PHE711C, PRO565B, PRO681C, SER678C, SER708B, SER708C, SER717B, THR249B, THR250B, THR250C, THR687C, TYR251B, TYR567B, TYR679C, TYR682C, TYR685C, TYR712B, TYR712C, TYR722C, VAL568B
• B-D: ALA224B, ALA224D, ARG226B, ARG226D, ASP229B, ASP229D
• C-D: ALA10C, ALA10D, ALA173C, ALA173D, ALA18C, ALA18D, ALA19C, ALA19D, ALA20C, ALA20D, ALA221D, ALA224C, ALA224D, ALA230C, ALA230D, ALA24C, ALA24D, ALA27C, ALA27D, ALA39C, ALA39D, ALA45C, ALA45D, ALA564C, ALA564D, ARG141C, ARG141D, ARG146C, ARG146D, ARG162C, ARG162D, ARG171C, ARG171D, ARG172C, ARG172D, ARG17C, ARG17D, ARG187C, ARG187D, ARG226C, ARG226D, ARG234C, ARG234D, ARG236C, ARG236D, ARG242C, ARG242D, ARG257C, ARG257D, ARG259C, ARG259D, ARG30C, ARG30D, ARG38C, ARG38D, ARG43C, ARG43D, ARG50C, ARG50D, ARG52C, ARG52D, ASN223C, ASN223D, ASN247C, ASN247D, ASP159C, ASP159D, ASP175C, ASP175D, ASP192C, ASP192D, ASP218C, ASP218D, ASP220C, ASP220D, ASP229C, ASP229D, ASP239C, ASP239D, ASP248C, ASP248D, ASP25C, ASP25D, ASP29C, ASP29D, ASP46C, ASP46D, ASP47C, ASP47D, CYS241C, CYS241D, GLN154C, GLN154D, GLN176C, GLN176D, GLN225C, GLN225D, GLN260C, GLN260D, GLN41C, GLN41D, GLU156C, GLU156D, GLU163C, GLU163D, GLU164C, GLU164D, GLU165C, GLU165D, GLU212C, GLU212D, GLU215C, GLU215D, GLU216C, GLU216D, GLU233C, GLU233D, GLU235C, GLU235D, GLU252C, GLU252D, GLU42C, GLU42D, GLU49C, GLU49D, GLU53C, GLU53D, GLY13C, GLY13D, GLY143C, GLY143D, GLY21C, GLY21D, GLY253C, GLY253D, GLY35C, GLY35D, GLY566C, GLY566D, HIS15C, HIS15D, ILE104C, ILE104D, ILE170C, ILE170D, ILE189C, ILE189D, ILE231C, ILE231D, ILE232C, ILE232D, ILE240C, ILE240D, ILE44C, ILE44D, LEU11C, LEU11D, LEU144C, LEU144D, LEU244C, LEU244D, LEU256C, LEU256D, LEU26C, LEU26D, LYS157C, LYS157D, LYS210C, LYS210D, LYS254C, LYS254D, LYS255C, LYS255D, LYS31C, LYS31D, LYS571C, LYS571D, PHE142C, PHE142D, PHE145C, PHE145D, PHE168C, PHE168D, PHE217C, PHE217D, PHE222C, PHE222D, PHE227C, PHE227D, PRO158C, PRO158D, PRO160C, PRO160D, PRO167C, PRO167D, PRO190C, PRO190D, PRO194C, PRO194D, PRO213C, PRO213D, PRO23C, PRO23D, PRO246C, PRO246D, PRO565C, PRO565D, SER14C, SER14D, SER174C, SER174D, SER238C, SER238D, SER37C, SER37D, THR169C, THR169D, THR228C, THR228D, THR22C, THR22D, THR249C, THR249D, THR250C, THR250D, THR28C, THR28D, THR34C, THR34D, TRP161C, TRP161D, TRP214C, TRP214D, TRP48C, TRP48D, TYR166C, TYR166D, TYR191C, TYR191D, TYR219C, TYR219D, TYR245C, TYR245D, TYR251C, TYR251D, VAL12C, VAL12D, VAL155C, VAL155D, VAL16C, VAL16D, VAL203C, VAL203D, VAL243C, VAL243D, VAL40C, VAL40D