2C46

crystal structure of the human rna guanylyltransferase and 5'-phosphatase

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 83
  • Norm. En. per Res.: -6.4882
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-122.7214	-253.5418	-242.115	-618.3782	104	15	0	7689	16	97	49
B-C	-75.0264	-301.5444	-161.952	-538.5228	83	9	0	5751	18	84	31
C-D	-2.453	25.934	-94.8628	-71.3818	63	2	4	4034	0	1	17

Interface residues

• A-D: ALA2A, ARG132A, ARG132D, ARG34D, ARG72A, ARG72D, ARG9A, ARG9D, ASN131A, ASN131D, ASN4A, ASN4D, ASN69A, ASN69D, ASP168A, ASP168D, ASP191A, ASP191D, ASP196A, ASP196D, ASP197A, ASP197D, ASP199A, ASP199D, ASP66A, ASP66D, CYS126A, CYS126D, CYS193A, CYS193D, CYS91A, CYS91D, GLN38D, GLN90A, GLN90D, GLU195A, GLU195D, GLU198A, GLU198D, GLU200D, GLU96A, GLU96D, GLY129A, GLY129D, GLY167A, GLY167D, GLY93A, GLY93D, GLY95A, GLY95D, HIS125A, HIS125D, HIS128A, HIS128D, HIS3A, HIS94A, HIS94D, ILE6D, LEU-4A, LEU189A, LEU189D, LEU67A, LEU67D, LEU89A, LEU89D, LYS166A, LYS166D, LYS5A, LYS5D, LYS88A, LYS92A, LYS92D, MET1A, PHE130A, PHE130D, PHE194A, PHE194D, PHE73A, PHE73D, PRO190A, PRO190D, PRO7A, PRO7D, PRO8A, PRO8D, SER37D, SER71A, THR127A, THR127D, THR133A, THR133D, THR29A, THR29D, THR68A, THR68D, THR70A, THR70D, TRP192A, TRP192D, TYR165A, TYR165D, TYR169A, TYR169D, TYR35D
• B-C: ARG132B, ARG132C, ARG72C, ARG9B, ARG9C, ASN131B, ASN131C, ASN69B, ASN69C, ASP196B, ASP196C, ASP197B, ASP197C, ASP199B, ASP199C, ASP66B, ASP66C, CYS126B, CYS126C, CYS193B, CYS193C, CYS91B, CYS91C, GLN90B, GLN90C, GLU195B, GLU195C, GLU198B, GLU198C, GLU96B, GLU96C, GLY129B, GLY129C, GLY93B, GLY93C, GLY95B, GLY95C, HIS125B, HIS125C, HIS128B, HIS128C, HIS94B, HIS94C, LEU188B, LEU188C, LEU189B, LEU189C, LEU67B, LEU67C, LEU89B, LEU89C, LYS166B, LYS166C, LYS92B, LYS92C, PHE130B, PHE130C, PHE194B, PHE194C, PHE73B, PHE73C, PRO186B, PRO186C, PRO7B, PRO7C, PRO8B, PRO8C, THR127B, THR127C, THR133B, THR133C, THR29B, THR29C, THR68B, THR68C, THR70B, THR70C, TRP192B, TRP192C, TYR165B, TYR165C, TYR169B, TYR169C
• C-D: ALA151C, ALA151D, ALA152C, ALA152D, ALA154C, ALA154D, ALA157C, ALA157D, ALA159C, ALA159D, ALA21C, ALA21D, ARG160C, ARG160D, ARG16C, ARG23C, ARG23D, ASP146C, GLN158C, GLN158D, GLN18C, GLN18D, GLU150C, GLU150D, GLU182C, GLU182D, GLY17C, GLY17D, GLY22C, GLY22D, ILE149C, ILE149D, LEU141C, LEU141D, LEU188D, LEU25C, LEU25D, MET145C, PHE156C, PHE156D, PHE174C, PHE174D, PHE24C, PHE24D, PRO161C, PRO161D, PRO184C, PRO184D, PRO185D, PRO19C, PRO19D, PRO26C, PRO26D, SER148C, SER148D, THR155C, THR155D, TRP147C, TRP147D, VAL153C, VAL153D, VAL20C, VAL20D