2C41

x-ray structure of dps from thermosynechococcus elongatus

• Total interactions analyzed: 66
• Total true interactions: 30
• Strongest Interaction:
  • Chains: I-L
  • Int. Res.: 67
  • Norm. En. per Res.: -5.1849
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-68.4827	-95.0605	-328.588	-492.1312	112	19	4	12589	10	32	20
A-D	-35.7371	-36.3424	-251.852	-323.9315	67	4	8	9075	3	20	26
A-E	-11.1164	-49.8482	-128.59	-189.5546	57	2	2	4789	4	25	17
A-F	-40.9995	-35.2867	-255.937	-332.2232	66	5	8	9120	3	19	26
A-I	-11.0929	-52.4376	-126.242	-189.7725	56	1	2	4728	4	25	18
B-D	-11.5679	-51.5088	-128.836	-191.9127	55	1	2	4761	4	25	17
B-I	-40.3461	-34.6918	-257.951	-332.9889	69	7	8	9173	3	20	26
B-K	-12.1345	-51.3777	-129.311	-192.8233	57	1	2	4788	4	25	17
B-L	-38.6834	-33.7615	-264.538	-336.9829	69	7	8	9299	3	20	26
C-D	-66.6335	-110.3826	-325.622	-502.6382	113	15	4	12606	10	32	19
C-F	-10.8655	-50.1084	-126.398	-187.3719	54	2	2	4702	4	25	17
C-G	-36.2529	-35.2049	-250.963	-322.4208	67	5	8	9136	3	20	26
C-H	-10.9768	-51.9572	-128.597	-191.531	56	2	2	4751	4	25	17
C-K	-36.4027	-34.9094	-256.557	-327.8692	68	4	8	9116	3	19	26
D-F	-37.9404	-35.6046	-252.93	-326.475	67	5	8	9062	3	20	26
D-K	-10.9891	-52.1302	-129.306	-192.4254	57	2	2	4821	4	25	17
E-F	-69.3049	-100.8579	-332.604	-502.7668	113	15	4	12643	10	32	18
E-H	-39.3044	-34.3299	-264.068	-337.7023	67	4	8	9181	3	20	26
E-I	-11.2305	-51.0667	-128.437	-190.7342	57	1	2	4797	4	25	17
E-J	-35.0834	-36.2077	-247.966	-319.2571	67	4	8	9028	3	19	26
F-H	-11.258	-50.961	-128.288	-190.507	56	3	2	4741	4	25	18
G-H	-65.0667	-81.8295	-325.853	-472.7492	111	14	4	12525	10	32	19
G-J	-12.0672	-50.9045	-127.554	-190.5257	56	2	2	4731	4	25	16
G-K	-41.1825	-35.7371	-249.821	-326.7406	66	5	8	9127	3	19	26
G-L	-11.5512	-50.6964	-128.59	-190.8376	56	0	2	4759	4	25	17
H-J	-44.2604	-35.8845	-250.882	-331.0269	66	6	8	9060	3	19	26
I-J	-68.0548	-111.0118	-315.626	-494.6926	114	29	4	12690	10	32	20
I-L	-49.8556	-35.6332	-261.9	-347.3887	67	8	8	9162	3	20	26
J-L	-10.8104	-50.1185	-124.904	-185.833	53	2	2	4681	4	25	17
K-L	-59.3891	-95.0968	-317.913	-472.3989	114	23	4	12536	10	32	20

Interface residues

• A-B: ALA20A, ALA20B, ALA57A, ALA57B, ALA63A, ALA63B, ALA75A, ALA75B, ALA78A, ALA78B, ASN28A, ASN28B, ASP60A, ASP60B, ASP76A, ASP76B, ASP79A, ASP79B, GLN19A, GLN19B, GLN72A, GLN72B, GLN92A, GLN92B, GLU101A, GLU101B, GLU49A, GLU49B, GLU61A, GLU61B, GLU64A, GLU64B, GLY52A, GLY52B, GLY71A, GLY71B, GLY91A, GLY91B, HIS33A, HIS33B, HIS45A, HIS45B, ILE59A, ILE59B, LEU27A, LEU27B, LEU35A, LEU35B, LEU62A, LEU62B, LEU67A, LEU67B, LEU81A, LEU81B, LEU93A, LEU93B, LYS30A, LYS30B, LYS31A, LYS31B, LYS82A, LYS82B, MET25A, MET25B, MET58A, MET58B, MET68A, MET68B, MET98A, MET98B, PHE41A, PHE41B, PHE56A, PHE56B, PRO73A, PRO73B, PRO77A, PRO77B, PRO88A, PRO88B, SER53A, SER53B, SER66A, SER66B, SER89A, SER89B, SER90A, SER90B, THR36A, THR36B, THR87A, THR87B, TRP34A, TRP34B, TYR26A, TYR26B, TYR29A, TYR29B, TYR32A, TYR32B, TYR37A, TYR37B, TYR80A, TYR80B, VAL23A, VAL23B, VAL24A, VAL24B, VAL74A, VAL74B, VAL86A, VAL86B
• A-D: ALA151A, ALA151D, ARG42A, ARG42D, ASP154A, ASP154D, ASP43A, ASP43D, GLN51D, GLN97A, GLU100A, GLU148A, GLU148D, GLU49D, GLU50D, GLY153D, GLY155A, GLY155D, GLY38A, GLY38D, HIS33A, HIS45A, HIS45D, ILE99A, ILE99D, LEU146A, LEU146D, LEU150A, LEU150D, LEU156A, LEU156D, LEU35A, LEU40A, LEU40D, LEU44A, LEU44D, LEU46A, LEU46D, LEU47D, LEU93A, LYS141D, LYS147D, LYS152A, LYS152D, LYS96A, LYS96D, MET98A, PHE145D, PHE149A, PHE149D, PHE41A, PHE41D, PHE48A, PHE48D, PRO39A, PRO39D, SER158A, SER158D, THR36A, THR94A, TRP144D, TRP34A, TYR37A, VAL157A, VAL157D, VAL95A, VAL95D
• A-E: ALA117A, ALA120E, ALA123E, ALA129A, ALA129E, ALA63E, ARG134A, ARG134E, ARG143A, ARG65E, ASP116A, ASP125E, ASP130A, ASP130E, ASP60E, ASP70E, GLN115A, GLN137A, GLN140A, GLN72E, GLU107A, GLU112A, GLU118A, GLU148A, GLU61E, GLU64E, GLY124E, GLY127E, GLY71E, HIS114A, HIS139A, HIS142A, ILE110A, ILE126E, LEU131A, LEU131E, LEU135A, LEU67E, LEU69E, LYS141A, LYS147A, LYS8E, MET113A, MET68E, PHE145A, PRO73E, SER66E, THR121A, THR121E, THR128E, THR133A, THR133E, THR138A, TRP144A, TYR132A, TYR132E, VAL136A
• A-F: ALA151A, ALA151F, ARG42A, ARG42F, ASP154A, ASP154F, ASP43A, ASP43F, GLN51A, GLN97F, GLU100F, GLU148A, GLU148F, GLU49A, GLU50A, GLY153A, GLY155A, GLY155F, GLY38A, GLY38F, HIS33F, HIS45A, HIS45F, ILE99A, ILE99F, LEU146A, LEU146F, LEU150A, LEU150F, LEU156A, LEU156F, LEU35F, LEU40A, LEU40F, LEU44A, LEU44F, LEU46A, LEU46F, LEU47A, LEU93F, LYS141A, LYS147A, LYS152A, LYS152F, LYS96F, MET98F, PHE145A, PHE149A, PHE149F, PHE41A, PHE41F, PHE48A, PHE48F, PRO39A, PRO39F, SER158A, SER158F, THR36F, THR94F, TRP144A, TRP34F, TYR37F, VAL157A, VAL157F, VAL95A, VAL95F
• A-I: ALA117I, ALA123A, ALA129A, ALA129I, ALA63A, ARG134A, ARG134I, ARG143I, ARG65A, ASP116I, ASP125A, ASP130A, ASP130I, ASP60A, ASP70A, GLN115I, GLN137I, GLN140I, GLU107I, GLU112I, GLU118I, GLU148I, GLU61A, GLU64A, GLY124A, GLY127A, GLY71A, HIS114I, HIS139I, HIS142I, ILE110I, ILE126A, LEU131A, LEU131I, LEU135I, LEU67A, LEU69A, LYS141I, LYS147I, LYS8A, MET113I, MET68A, PHE145I, PRO73A, SER66A, THR111I, THR121A, THR121I, THR128A, THR133A, THR133I, THR138I, TRP144I, TYR132A, TYR132I, VAL136I
• B-D: ALA117D, ALA123B, ALA129B, ALA129D, ALA63B, ARG134B, ARG134D, ARG143D, ARG65B, ASP116D, ASP125B, ASP130B, ASP130D, ASP60B, ASP70B, GLN115D, GLN137D, GLN140D, GLN72B, GLU107D, GLU118D, GLU148D, GLU61B, GLU64B, GLY124B, GLY127B, GLY71B, HIS114D, HIS139D, HIS142D, ILE110D, ILE126B, LEU131B, LEU131D, LEU135D, LEU67B, LEU69B, LYS141D, LYS147D, LYS8B, MET113D, MET68B, PHE145D, PRO73B, SER66B, THR121B, THR121D, THR128B, THR133B, THR133D, THR138D, TRP144D, TYR132B, TYR132D, VAL136D
• B-I: ALA151B, ALA151I, ARG42B, ARG42I, ASP154B, ASP154I, ASP43B, ASP43I, GLN51I, GLN97B, GLU100B, GLU148B, GLU148I, GLU49I, GLU50I, GLY153I, GLY155B, GLY155I, GLY38B, GLY38I, HIS142I, HIS33B, HIS45B, HIS45I, ILE99B, ILE99I, LEU146B, LEU146I, LEU150B, LEU150I, LEU156B, LEU156I, LEU35B, LEU40B, LEU40I, LEU44B, LEU44I, LEU46B, LEU46I, LEU47I, LEU93B, LYS141I, LYS147I, LYS152B, LYS152I, LYS96B, LYS96I, MET98B, PHE145I, PHE149B, PHE149I, PHE41B, PHE41I, PHE48B, PHE48I, PRO39B, PRO39I, SER158B, SER158I, THR36B, THR94B, TRP144I, TRP34B, TYR32B, TYR37B, VAL157B, VAL157I, VAL95B, VAL95I
• B-K: ALA117B, ALA123K, ALA129B, ALA129K, ALA63K, ARG134B, ARG134K, ARG143B, ARG65K, ASP116B, ASP125K, ASP130B, ASP130K, ASP60K, ASP70K, GLN115B, GLN137B, GLN140B, GLN72K, GLU107B, GLU112B, GLU118B, GLU148B, GLU61K, GLU64K, GLY124K, GLY127K, GLY71K, HIS114B, HIS139B, HIS142B, ILE110B, ILE126K, LEU131B, LEU131K, LEU135B, LEU67K, LEU69K, LYS141B, LYS147B, LYS8K, MET113B, MET68K, PHE145B, PRO73K, SER66K, THR121B, THR121K, THR128B, THR128K, THR133B, THR133K, THR138B, TRP144B, TYR132B, TYR132K, VAL136B
• B-L: ALA151B, ALA151L, ARG42B, ARG42L, ASP154B, ASP154L, ASP43B, ASP43L, GLN51B, GLN97L, GLU100L, GLU148B, GLU148L, GLU49B, GLU50B, GLY153B, GLY155B, GLY155L, GLY38B, GLY38L, HIS33L, HIS45B, HIS45L, ILE99B, ILE99L, LEU146B, LEU146L, LEU150B, LEU150L, LEU156B, LEU156L, LEU35L, LEU40B, LEU40L, LEU44B, LEU44L, LEU46B, LEU46L, LEU47B, LEU47L, LEU93L, LYS141B, LYS147B, LYS152B, LYS152L, LYS96B, LYS96L, MET98L, PHE145B, PHE149B, PHE149L, PHE41B, PHE41L, PHE48B, PHE48L, PRO39B, PRO39L, SER158B, SER158L, THR36L, THR94L, TRP144B, TRP34L, TYR32L, TYR37L, VAL157B, VAL157L, VAL95B, VAL95L
• C-D: ALA20C, ALA20D, ALA22D, ALA57C, ALA57D, ALA63C, ALA63D, ALA75C, ALA75D, ALA78C, ALA78D, ASN28C, ASN28D, ASP60C, ASP60D, ASP76C, ASP76D, ASP79C, ASP79D, GLN19C, GLN19D, GLN72C, GLN72D, GLN92C, GLN92D, GLU101C, GLU101D, GLU49C, GLU49D, GLU61C, GLU61D, GLU64C, GLU64D, GLY52C, GLY52D, GLY71C, GLY71D, GLY91C, GLY91D, HIS33C, HIS33D, HIS45C, HIS45D, ILE59C, ILE59D, LEU27C, LEU27D, LEU35C, LEU35D, LEU62C, LEU62D, LEU67C, LEU67D, LEU81C, LEU81D, LEU93C, LEU93D, LYS30C, LYS30D, LYS31C, LYS31D, LYS82C, LYS82D, MET25C, MET25D, MET58C, MET58D, MET68C, MET68D, MET98C, MET98D, PHE41C, PHE41D, PHE56C, PHE56D, PRO73C, PRO73D, PRO77C, PRO77D, PRO88C, PRO88D, SER53C, SER53D, SER66C, SER66D, SER89C, SER89D, SER90C, SER90D, THR36C, THR36D, THR87C, THR87D, TRP34C, TRP34D, TYR26C, TYR26D, TYR29C, TYR29D, TYR32C, TYR32D, TYR37C, TYR37D, TYR80C, TYR80D, VAL23C, VAL23D, VAL24C, VAL24D, VAL74C, VAL74D, VAL86C, VAL86D
• C-F: ALA117F, ALA123C, ALA129C, ALA129F, ALA63C, ARG134C, ARG134F, ARG143F, ARG65C, ASP116F, ASP125C, ASP130C, ASP130F, ASP60C, ASP70C, GLN115F, GLN137F, GLN140F, GLU107F, GLU118F, GLU148F, GLU61C, GLU64C, GLY124C, GLY127C, GLY71C, HIS114F, HIS139F, HIS142F, ILE110F, ILE126C, LEU131C, LEU131F, LEU135F, LEU67C, LEU69C, LYS141F, LYS147F, LYS8C, MET113F, MET68C, PHE145F, PRO73C, SER66C, THR121C, THR121F, THR128C, THR133C, THR133F, THR138F, TRP144F, TYR132C, TYR132F, VAL136F
• C-G: ALA151C, ALA151G, ARG42C, ARG42G, ASP154C, ASP154G, ASP43C, ASP43G, GLN51C, GLN97G, GLU100G, GLU148C, GLU148G, GLU49C, GLU50C, GLY153C, GLY155C, GLY155G, GLY38C, GLY38G, HIS33G, HIS45C, HIS45G, ILE99C, ILE99G, LEU146C, LEU146G, LEU150C, LEU150G, LEU156C, LEU156G, LEU35G, LEU40C, LEU40G, LEU44C, LEU44G, LEU46C, LEU46G, LEU47C, LEU93G, LYS141C, LYS147C, LYS152C, LYS152G, LYS96C, LYS96G, MET98G, PHE145C, PHE149C, PHE149G, PHE41C, PHE41G, PHE48C, PHE48G, PRO39C, PRO39G, SER158C, SER158G, THR36G, THR94G, TRP144C, TRP34G, TYR37G, VAL157C, VAL157G, VAL95C, VAL95G
• C-H: ALA117C, ALA123H, ALA129C, ALA129H, ALA63H, ARG134C, ARG134H, ARG143C, ARG65H, ASP116C, ASP125H, ASP130C, ASP130H, ASP60H, ASP70H, GLN115C, GLN137C, GLN140C, GLU107C, GLU112C, GLU118C, GLU148C, GLU61H, GLU64H, GLY124H, GLY127H, GLY71H, HIS114C, HIS139C, HIS142C, ILE110C, ILE126H, LEU131C, LEU131H, LEU135C, LEU135H, LEU67H, LEU69H, LYS141C, LYS147C, LYS8H, MET113C, MET68H, PHE145C, PRO73H, SER66H, THR121C, THR121H, THR128H, THR133C, THR133H, THR138C, TRP144C, TYR132C, TYR132H, VAL136C
• C-K: ALA151C, ALA151K, ARG42C, ARG42K, ASP154C, ASP154K, ASP43C, ASP43K, GLN51K, GLN97C, GLU100C, GLU148C, GLU148K, GLU49K, GLU50K, GLY153K, GLY155C, GLY155K, GLY38C, GLY38K, HIS33C, HIS45C, HIS45K, ILE99C, ILE99K, LEU146C, LEU146K, LEU150C, LEU150K, LEU156C, LEU156K, LEU35C, LEU40C, LEU40K, LEU44C, LEU44K, LEU46C, LEU46K, LEU47K, LEU93C, LYS141K, LYS147K, LYS152C, LYS152K, LYS96C, LYS96K, MET98C, PHE145K, PHE149C, PHE149K, PHE41C, PHE41K, PHE48C, PHE48K, PRO39C, PRO39K, SER158C, SER158K, THR36C, THR94C, TRP144K, TRP34C, TYR32C, TYR37C, VAL157C, VAL157K, VAL95C, VAL95K
• D-F: ALA151D, ALA151F, ARG42D, ARG42F, ASP154D, ASP154F, ASP43D, ASP43F, GLN51F, GLN97D, GLU100D, GLU148D, GLU148F, GLU49F, GLU50F, GLY153F, GLY155D, GLY155F, GLY38D, GLY38F, HIS33D, HIS45D, HIS45F, ILE99D, ILE99F, LEU146D, LEU146F, LEU150D, LEU150F, LEU156D, LEU156F, LEU35D, LEU40D, LEU40F, LEU44D, LEU44F, LEU46D, LEU46F, LEU47F, LEU93D, LYS141F, LYS147F, LYS152D, LYS152F, LYS96D, LYS96F, MET98D, PHE145F, PHE149D, PHE149F, PHE41D, PHE41F, PHE48D, PHE48F, PRO39D, PRO39F, SER158D, SER158F, THR36D, THR94D, TRP144F, TRP34D, TYR37D, VAL157D, VAL157F, VAL95D, VAL95F
• D-K: ALA117K, ALA123D, ALA129D, ALA129K, ALA63D, ARG134D, ARG134K, ARG143K, ARG65D, ASP116K, ASP125D, ASP130D, ASP130K, ASP60D, ASP70D, GLN115K, GLN137K, GLN140K, GLN72D, GLU107K, GLU112K, GLU118K, GLU148K, GLU61D, GLU64D, GLY124D, GLY127D, GLY71D, HIS114K, HIS139K, HIS142K, ILE110K, ILE126D, LEU131D, LEU131K, LEU135K, LEU67D, LEU69D, LYS141K, LYS147K, LYS8D, MET113K, MET68D, PHE145K, PRO73D, SER66D, THR111K, THR121D, THR121K, THR128D, THR133D, THR133K, THR138K, TRP144K, TYR132D, TYR132K, VAL136K
• E-F: ALA20E, ALA20F, ALA57E, ALA57F, ALA63E, ALA63F, ALA75E, ALA75F, ALA78E, ALA78F, ARG65F, ASN28E, ASN28F, ASP60E, ASP60F, ASP76E, ASP76F, ASP79E, ASP79F, GLN19E, GLN19F, GLN72E, GLN72F, GLN92E, GLN92F, GLU101E, GLU101F, GLU49E, GLU49F, GLU61E, GLU61F, GLU64E, GLU64F, GLY52E, GLY52F, GLY71E, GLY71F, GLY91E, GLY91F, HIS33E, HIS33F, HIS45E, HIS45F, ILE59E, ILE59F, LEU27E, LEU27F, LEU35E, LEU35F, LEU62E, LEU62F, LEU67E, LEU67F, LEU81E, LEU81F, LEU93E, LEU93F, LYS16F, LYS30E, LYS30F, LYS31E, LYS31F, LYS82E, LYS82F, MET25E, MET25F, MET58E, MET58F, MET68F, MET98E, MET98F, PHE41E, PHE41F, PHE56E, PHE56F, PRO73E, PRO73F, PRO77E, PRO77F, PRO88E, PRO88F, SER53E, SER53F, SER66E, SER66F, SER89E, SER89F, SER90E, SER90F, THR36E, THR36F, THR87E, THR87F, TRP34E, TRP34F, TYR26E, TYR26F, TYR29E, TYR29F, TYR32E, TYR32F, TYR37E, TYR37F, TYR80E, TYR80F, VAL23E, VAL23F, VAL24E, VAL24F, VAL74E, VAL74F, VAL86E, VAL86F
• E-H: ALA151E, ALA151H, ARG42E, ARG42H, ASP154E, ASP154H, ASP43E, ASP43H, GLN51H, GLN97E, GLU100E, GLU148E, GLU148H, GLU49H, GLU50H, GLY153H, GLY155E, GLY155H, GLY38E, GLY38H, HIS33E, HIS45E, HIS45H, ILE99E, ILE99H, LEU146E, LEU146H, LEU150E, LEU150H, LEU156E, LEU156H, LEU35E, LEU40E, LEU40H, LEU44E, LEU44H, LEU46E, LEU46H, LEU47H, LEU93E, LYS141H, LYS147H, LYS152E, LYS152H, LYS96E, LYS96H, MET98E, PHE145H, PHE149E, PHE149H, PHE41E, PHE41H, PHE48E, PHE48H, PRO39E, PRO39H, SER158E, SER158H, THR36E, THR94E, TRP144H, TRP34E, TYR37E, VAL157E, VAL157H, VAL95E, VAL95H
• E-I: ALA117E, ALA123I, ALA129E, ALA129I, ALA63I, ARG134E, ARG134I, ARG143E, ARG65I, ASP116E, ASP125I, ASP130E, ASP130I, ASP60I, ASP70I, GLN115E, GLN137E, GLN140E, GLN72I, GLU107E, GLU112E, GLU118E, GLU148E, GLU61I, GLU64I, GLY124I, GLY127I, GLY71I, HIS114E, HIS139E, HIS142E, ILE110E, ILE126I, LEU131E, LEU131I, LEU135E, LEU135I, LEU67I, LEU69I, LYS141E, LYS147E, MET113E, MET68I, PHE145E, PRO73I, SER66I, THR121E, THR121I, THR128E, THR128I, THR133E, THR133I, THR138E, TRP144E, TYR132E, TYR132I, VAL136E
• E-J: ALA151E, ALA151J, ARG42E, ARG42J, ASP154E, ASP154J, ASP43E, ASP43J, GLN51E, GLN97J, GLU100J, GLU148E, GLU148J, GLU49E, GLU50E, GLY153E, GLY155E, GLY155J, GLY38E, GLY38J, HIS33J, HIS45E, HIS45J, ILE99E, ILE99J, LEU146E, LEU146J, LEU150E, LEU150J, LEU156E, LEU156J, LEU35J, LEU40E, LEU40J, LEU44E, LEU44J, LEU46E, LEU46J, LEU47E, LEU93J, LYS141E, LYS147E, LYS152E, LYS152J, LYS96E, LYS96J, MET98J, PHE145E, PHE149E, PHE149J, PHE41E, PHE41J, PHE48E, PHE48J, PRO39E, PRO39J, SER158E, SER158J, THR36J, THR94J, TRP144E, TRP34J, TYR37J, VAL157E, VAL157J, VAL95E, VAL95J
• F-H: ALA117H, ALA123F, ALA129F, ALA129H, ALA63F, ARG134F, ARG134H, ARG143H, ARG65F, ASP116H, ASP125F, ASP130F, ASP130H, ASP60F, ASP70F, GLN115H, GLN137H, GLN140H, GLN72F, GLU107H, GLU112H, GLU118H, GLU148H, GLU61F, GLU64F, GLY124F, GLY127F, GLY71F, HIS114H, HIS139H, HIS142H, ILE110H, ILE126F, LEU131F, LEU131H, LEU135H, LEU67F, LEU69F, LYS141H, LYS147H, LYS8F, MET113H, MET68F, PHE145H, PRO73F, SER66F, THR121F, THR121H, THR128F, THR133F, THR133H, THR138H, TRP144H, TYR132F, TYR132H, VAL136H
• G-H: ALA20G, ALA20H, ALA57G, ALA57H, ALA63G, ALA63H, ALA75G, ALA75H, ALA78G, ALA78H, ASN28G, ASN28H, ASP60G, ASP60H, ASP76G, ASP76H, ASP79G, ASP79H, GLN19G, GLN19H, GLN72G, GLN72H, GLN92G, GLN92H, GLU101G, GLU101H, GLU49G, GLU49H, GLU61G, GLU61H, GLU64G, GLU64H, GLY52G, GLY52H, GLY71G, GLY71H, GLY91G, GLY91H, HIS33G, HIS33H, HIS45G, HIS45H, ILE59G, ILE59H, LEU27G, LEU27H, LEU35G, LEU35H, LEU62G, LEU62H, LEU67G, LEU67H, LEU81G, LEU81H, LEU93G, LEU93H, LYS30G, LYS30H, LYS31G, LYS31H, LYS82G, LYS82H, MET25G, MET25H, MET58G, MET58H, MET68H, MET98G, MET98H, PHE41G, PHE41H, PHE56G, PHE56H, PRO73G, PRO73H, PRO77G, PRO77H, PRO88G, PRO88H, SER53G, SER53H, SER66G, SER66H, SER89G, SER89H, SER90G, SER90H, THR36G, THR36H, THR87G, THR87H, TRP34G, TRP34H, TYR26G, TYR26H, TYR29G, TYR29H, TYR32G, TYR32H, TYR37G, TYR37H, TYR80G, TYR80H, VAL23G, VAL23H, VAL24G, VAL24H, VAL74G, VAL74H, VAL86G, VAL86H
• G-J: ALA117J, ALA123G, ALA129G, ALA129J, ALA63G, ARG134G, ARG134J, ARG143J, ARG65G, ASP116J, ASP125G, ASP130G, ASP130J, ASP60G, ASP70G, GLN115J, GLN137J, GLN140J, GLN72G, GLU107J, GLU112J, GLU118J, GLU148J, GLU61G, GLU64G, GLY124G, GLY127G, GLY71G, HIS114J, HIS139J, HIS142J, ILE110J, ILE126G, LEU131G, LEU131J, LEU135J, LEU67G, LEU69G, LYS141J, LYS147J, LYS8G, MET113J, MET68G, PHE145J, PRO73G, SER66G, THR121G, THR121J, THR128G, THR133G, THR133J, THR138J, TRP144J, TYR132G, TYR132J, VAL136J
• G-K: ALA151G, ALA151K, ARG42G, ARG42K, ASP154G, ASP154K, ASP43G, ASP43K, GLN51G, GLN97K, GLU100K, GLU148G, GLU148K, GLU49G, GLU50G, GLY153G, GLY155G, GLY155K, GLY38G, GLY38K, HIS33K, HIS45G, HIS45K, ILE99G, ILE99K, LEU146G, LEU146K, LEU150G, LEU150K, LEU156G, LEU156K, LEU35K, LEU40G, LEU40K, LEU44G, LEU44K, LEU46G, LEU46K, LEU47G, LEU93K, LYS141G, LYS147G, LYS152G, LYS152K, LYS96K, MET98K, PHE145G, PHE149G, PHE149K, PHE41G, PHE41K, PHE48G, PHE48K, PRO39G, PRO39K, SER158G, SER158K, THR36K, THR94K, TRP144G, TRP34K, TYR37K, VAL157G, VAL157K, VAL95G, VAL95K
• G-L: ALA117G, ALA123L, ALA129G, ALA129L, ALA63L, ARG134G, ARG134L, ARG143G, ARG65L, ASP116G, ASP125L, ASP130G, ASP130L, ASP60L, ASP70L, GLN115G, GLN137G, GLN140G, GLU107G, GLU112G, GLU118G, GLU148G, GLU61L, GLU64L, GLY124L, GLY127L, GLY71L, HIS114G, HIS139G, HIS142G, ILE110G, ILE126L, LEU131G, LEU131L, LEU135G, LEU67L, LEU69L, LYS141G, LYS147G, LYS8L, MET113G, MET68L, PHE145G, PRO73L, SER66L, THR121G, THR121L, THR128L, THR133G, THR133L, THR138G, THR4L, TRP144G, TYR132G, TYR132L, VAL136G
• H-J: ALA151H, ALA151J, ARG42H, ARG42J, ASP154H, ASP154J, ASP43H, ASP43J, GLN51J, GLN97H, GLU100H, GLU148H, GLU148J, GLU49J, GLU50J, GLY153J, GLY155H, GLY155J, GLY38H, GLY38J, HIS33H, HIS45H, HIS45J, ILE99H, ILE99J, LEU146H, LEU146J, LEU150H, LEU150J, LEU156H, LEU156J, LEU35H, LEU40H, LEU40J, LEU44H, LEU44J, LEU46H, LEU46J, LEU47J, LEU93H, LYS141J, LYS147J, LYS152H, LYS152J, LYS96H, MET98H, PHE145J, PHE149H, PHE149J, PHE41H, PHE41J, PHE48H, PHE48J, PRO39H, PRO39J, SER158H, SER158J, THR36H, THR94H, TRP144J, TRP34H, TYR37H, VAL157H, VAL157J, VAL95H, VAL95J
• I-J: ALA20I, ALA20J, ALA22I, ALA57I, ALA57J, ALA63I, ALA63J, ALA75I, ALA75J, ALA78I, ALA78J, ASN28I, ASN28J, ASP60I, ASP60J, ASP76I, ASP76J, ASP79I, ASP79J, GLN19I, GLN19J, GLN72I, GLN72J, GLN92I, GLN92J, GLU101I, GLU101J, GLU49I, GLU49J, GLU61I, GLU61J, GLU64I, GLU64J, GLY52I, GLY52J, GLY71I, GLY71J, GLY91I, GLY91J, HIS33I, HIS33J, HIS45I, HIS45J, ILE59I, ILE59J, LEU27I, LEU27J, LEU35I, LEU35J, LEU62I, LEU62J, LEU67I, LEU67J, LEU81I, LEU81J, LEU93I, LEU93J, LYS16I, LYS30I, LYS30J, LYS31I, LYS31J, LYS82I, LYS82J, MET25I, MET25J, MET58I, MET58J, MET68I, MET68J, MET98I, MET98J, PHE41I, PHE41J, PHE56I, PHE56J, PRO73I, PRO73J, PRO77I, PRO77J, PRO88I, PRO88J, SER53I, SER53J, SER66I, SER66J, SER89I, SER89J, SER90I, SER90J, THR36I, THR36J, THR87I, THR87J, TRP34I, TRP34J, TYR26I, TYR26J, TYR29I, TYR29J, TYR32I, TYR32J, TYR37I, TYR37J, TYR80I, TYR80J, VAL23I, VAL23J, VAL24I, VAL24J, VAL74I, VAL74J, VAL86I, VAL86J
• I-L: ALA151I, ALA151L, ARG42I, ARG42L, ASP154I, ASP154L, ASP43I, ASP43L, GLN51L, GLN97I, GLU100I, GLU148I, GLU148L, GLU49L, GLU50L, GLY153L, GLY155I, GLY155L, GLY38I, GLY38L, HIS33I, HIS45I, HIS45L, ILE99I, ILE99L, LEU146I, LEU146L, LEU150I, LEU150L, LEU156I, LEU156L, LEU35I, LEU40I, LEU40L, LEU44I, LEU44L, LEU46I, LEU46L, LEU47L, LEU93I, LYS141L, LYS147L, LYS152I, LYS152L, LYS96I, LYS96L, MET98I, PHE145L, PHE149I, PHE149L, PHE41I, PHE41L, PHE48I, PHE48L, PRO39I, PRO39L, SER158I, SER158L, THR36I, THR94I, TRP144L, TRP34I, TYR37I, VAL157I, VAL157L, VAL95I, VAL95L
• J-L: ALA117L, ALA123J, ALA129J, ALA129L, ALA63J, ARG134J, ARG134L, ARG143L, ARG65J, ASP116L, ASP125J, ASP130J, ASP130L, ASP60J, ASP70J, GLN115L, GLN137L, GLN140L, GLU107L, GLU118L, GLU148L, GLU61J, GLU64J, GLY124J, GLY127J, GLY71J, HIS114L, HIS139L, HIS142L, ILE110L, ILE126J, LEU131J, LEU131L, LEU135L, LEU67J, LEU69J, LYS141L, LYS147L, MET113L, MET68J, PHE145L, PRO73J, SER66J, THR121J, THR121L, THR128J, THR133J, THR133L, THR138L, TRP144L, TYR132J, TYR132L, VAL136L
• K-L: ALA20K, ALA20L, ALA22K, ALA57K, ALA57L, ALA63K, ALA63L, ALA75K, ALA75L, ALA78K, ALA78L, ASN28K, ASN28L, ASP60K, ASP60L, ASP76K, ASP76L, ASP79K, ASP79L, GLN19K, GLN19L, GLN72K, GLN72L, GLN92K, GLN92L, GLU101K, GLU101L, GLU49K, GLU49L, GLU61K, GLU61L, GLU64K, GLU64L, GLY52K, GLY52L, GLY71K, GLY71L, GLY91K, GLY91L, HIS33K, HIS33L, HIS45K, HIS45L, ILE59K, ILE59L, LEU27K, LEU27L, LEU35K, LEU35L, LEU62K, LEU62L, LEU67K, LEU67L, LEU81K, LEU81L, LEU93K, LEU93L, LYS16L, LYS30K, LYS30L, LYS31K, LYS31L, LYS82K, LYS82L, MET25K, MET25L, MET58K, MET58L, MET68K, MET68L, MET98K, MET98L, PHE41K, PHE41L, PHE56K, PHE56L, PRO73K, PRO73L, PRO77K, PRO77L, PRO88K, PRO88L, SER53K, SER53L, SER66K, SER66L, SER89K, SER89L, SER90K, SER90L, THR36K, THR36L, THR87K, THR87L, TRP34K, TRP34L, TYR26K, TYR26L, TYR29K, TYR29L, TYR32K, TYR32L, TYR37K, TYR37L, TYR80K, TYR80L, VAL23K, VAL23L, VAL24K, VAL24L, VAL74K, VAL74L, VAL86K, VAL86L