2C35

subunits rpb4 and rpb7 of human rna polymerase ii

• Total interactions analyzed: 28
• Total true interactions: 12
• Strongest Interaction:
  • Chains: G-H
  • Int. Res.: 153
  • Norm. En. per Res.: -4.5326
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-91.9843	-76.0075	-469.294	-637.2857	151	34	23	19221	11	56	37
A-D	-6.7423	-14.6132	-76.4791	-97.8347	38	2	0	2491	1	25	12
A-H	0.0	-8.8775	-6.3257	-15.2032	10	0	0	319	0	11	6
B-E	0.0	0.0	-0.3461	-0.3461	3	0	0	69	0	1	2
B-F	-37.7733	-29.8728	-198.215	-265.861	93	22	4	9312	5	29	31
B-G	0.0	0.0	-0.0825	-0.0825	5	0	0	24	0	0	0
B-H	0.0	4.9791	-13.922	-8.9429	15	0	0	686	0	11	4
C-D	-89.6582	-76.2202	-467.962	-633.8404	151	33	23	19220	11	56	37
D-G	0.0	0.0	-0.2471	-0.2471	3	0	0	57	0	1	1
D-H	-31.2803	-28.2532	-224.006	-283.5394	93	20	3	9515	5	29	32
E-F	-105.6169	-111.927	-472.658	-690.2019	153	30	22	19199	11	57	38
G-H	-106.0348	-111.9281	-475.531	-693.4939	153	30	22	19175	11	57	38

Interface residues

• A-B: ALA101A, ALA108A, ALA113A, ALA17A, ALA29A, ALA47B, ALA74B, ALA87B, ALA98A, ARG138A, ARG144B, ARG44A, ARG70A, ARG73A, ARG78B, ARG84A, ASN102A, ASN34A, ASN48A, ASN66A, ASP140B, ASP141B, ASP156B, ASP165B, ASP166B, ASP16A, ASP53A, ASP86B, CYS104A, CYS38B, CYS99A, GLN135A, GLN139B, GLN19A, GLN28B, GLN47A, GLN55A, GLU100B, GLU106A, GLU109A, GLU110A, GLU142B, GLU14A, GLU15A, GLU25A, GLU27A, GLU30A, GLU35B, GLU36A, GLU42A, GLU54A, GLU59A, GLU83B, GLU96A, GLY102B, GLY149B, GLY169B, GLY36B, GLY40B, GLY43B, GLY82B, HIS38A, HIS43A, HIS4B, HIS93A, ILE101B, ILE115A, ILE143B, ILE147B, ILE157B, ILE21A, ILE46B, ILE5B, ILE75B, LEU100A, LEU103A, LEU114A, LEU145B, LEU168B, LEU20A, LEU32A, LEU33A, LEU40A, LEU41A, LEU57A, LEU65A, LEU7B, LEU97A, LYS112A, LYS146B, LYS24A, LYS27B, LYS41B, LYS45A, LYS63A, LYS73B, LYS81B, LYS94A, MET104B, MET1B, MET39A, MET62A, PHE22A, PHE26A, PHE2B, PHE31B, PHE44B, PHE61A, PHE71A, PHE77B, PHE80B, PHE95A, PRO103B, PRO105A, PRO116A, PRO23A, PRO79B, SER105B, SER111A, SER18A, SER35A, SER58A, SER6B, THR107A, THR150B, THR28A, THR31A, THR32B, THR37B, THR39B, THR49B, THR50B, THR64A, THR68A, THR90B, THR99B, TYR167B, TYR3B, TYR42B, TYR67A, VAL171B, VAL34B, VAL37A, VAL45B, VAL48B, VAL60A, VAL76B, VAL84B, VAL85B, VAL88B, VAL89B
• A-D: ARG138A, ARG16D, ARG63D, ASN155D, ASP132A, ASP133A, GLN128A, GLN129A, GLN135A, GLN141A, GLN60D, GLU106A, GLU10D, GLU125A, GLU126A, GLU33D, GLU78A, GLY62D, GLY64D, HIS14D, ILE11D, ILE130A, ILE134A, LEU127A, LEU12D, LEU131A, LEU13D, LEU67D, LYS137A, LYS154D, LYS29D, PHE140A, PHE65D, PRO15D, PRO61D, SER139A, THR136A, TYR17D
• A-H: ARG44A, ASP132H, ASP134H, GLN47A, GLU116H, HIS43A, LEU40A, MET131H, MET39A, THR130H
• B-E: GLU59E, LYS63E, LYS94B
• B-F: ALA159B, ALA159F, ARG110B, ARG110F, ARG151B, ARG151F, ASN122F, ASN155F, ASN93B, ASN93F, ASP120B, ASP120F, ASP153B, ASP153F, ASP156B, ASP156F, CYS106B, CYS106F, GLN91B, GLN91F, GLU100B, GLU100F, GLU116B, GLU118B, GLU118F, GLY102F, GLY149B, GLY149F, GLY161B, GLY96B, GLY96F, HIS111B, HIS111F, ILE101F, ILE108B, ILE108F, ILE113B, ILE113F, ILE157B, ILE157F, ILE160B, ILE160F, LEU97B, LEU97F, LYS129B, LYS154B, LYS154F, LYS81F, LYS94B, LYS94F, MET104B, MET104F, MET117B, MET131B, MET164B, PHE107B, PHE107F, PHE119B, PHE119F, PHE158B, PHE158F, PHE44B, PHE44F, PHE98B, PHE98F, PRO103B, PRO103F, PRO114B, PRO114F, PRO121B, PRO121F, SER105B, SER105F, SER109B, SER109F, SER112B, SER112F, SER115B, SER115F, THR130B, THR150B, THR150F, THR90F, THR99B, THR99F, TYR128B, TYR128F, VAL148B, VAL148F, VAL152B, VAL152F, VAL95B, VAL95F
• B-G: ASN21B, GLU106G, LEU23B, PRO20B, THR107G
• B-H: ASP132H, ASP134H, ASP52B, GLU133H, HIS4B, ILE135H, ILE51B, LYS73B, MET131H, PHE31B, THR130H, THR49B, THR50B, VAL136H, VAL48B
• C-D: ALA101C, ALA108C, ALA113C, ALA17C, ALA29C, ALA47D, ALA74D, ALA87D, ALA98C, ARG138C, ARG144D, ARG44C, ARG70C, ARG73C, ARG78D, ARG84C, ASN102C, ASN34C, ASN48C, ASN66C, ASP140D, ASP141D, ASP156D, ASP165D, ASP166D, ASP16C, ASP53C, ASP86D, CYS104C, CYS38D, CYS99C, GLN135C, GLN139D, GLN19C, GLN28D, GLN47C, GLN55C, GLU100D, GLU106C, GLU109C, GLU110C, GLU142D, GLU14C, GLU15C, GLU25C, GLU27C, GLU30C, GLU35D, GLU36C, GLU42C, GLU54C, GLU59C, GLU83D, GLU96C, GLY102D, GLY149D, GLY169D, GLY36D, GLY40D, GLY43D, GLY82D, HIS38C, HIS43C, HIS4D, HIS93C, ILE101D, ILE115C, ILE143D, ILE147D, ILE157D, ILE21C, ILE46D, ILE5D, ILE75D, LEU100C, LEU103C, LEU114C, LEU145D, LEU168D, LEU20C, LEU32C, LEU33C, LEU40C, LEU41C, LEU57C, LEU65C, LEU7D, LEU97C, LYS112C, LYS146D, LYS24C, LYS27D, LYS41D, LYS45C, LYS63C, LYS73D, LYS81D, LYS94C, MET104D, MET1D, MET39C, MET62C, PHE22C, PHE26C, PHE2D, PHE31D, PHE44D, PHE61C, PHE71C, PHE77D, PHE80D, PHE95C, PRO103D, PRO105C, PRO116C, PRO23C, PRO79D, SER105D, SER111C, SER18C, SER35C, SER58C, SER6D, THR107C, THR150D, THR28C, THR31C, THR32D, THR37D, THR39D, THR49D, THR50D, THR64C, THR68C, THR90D, THR99D, TYR167D, TYR3D, TYR42D, TYR67C, VAL171D, VAL34D, VAL37C, VAL45D, VAL48D, VAL60C, VAL76D, VAL84D, VAL85D, VAL88D, VAL89D
• D-G: GLU59G, LYS63G, LYS94D
• D-H: ALA159D, ALA159H, ARG110D, ARG110H, ARG151D, ARG151H, ASN122H, ASN155H, ASN93D, ASN93H, ASP120D, ASP120H, ASP153D, ASP153H, ASP156D, ASP156H, CYS106D, CYS106H, GLN91D, GLN91H, GLU100D, GLU100H, GLU116D, GLU118D, GLU118H, GLY102H, GLY149D, GLY149H, GLY161D, GLY96D, GLY96H, HIS111D, HIS111H, ILE101H, ILE108D, ILE108H, ILE113D, ILE113H, ILE157D, ILE157H, ILE160D, ILE160H, LEU97D, LEU97H, LYS129D, LYS154D, LYS154H, LYS81H, LYS94D, LYS94H, MET104D, MET104H, MET117D, MET131D, MET164D, PHE107D, PHE107H, PHE119D, PHE119H, PHE158D, PHE158H, PHE44D, PHE44H, PHE98D, PHE98H, PRO103D, PRO103H, PRO114D, PRO114H, PRO121D, PRO121H, SER105D, SER105H, SER109D, SER109H, SER112D, SER112H, SER115D, SER115H, THR130D, THR150D, THR150H, THR90H, THR99D, THR99H, TYR128D, TYR128H, VAL148D, VAL148H, VAL152D, VAL152H, VAL95D, VAL95H
• E-F: ALA101E, ALA108E, ALA113E, ALA17E, ALA29E, ALA47F, ALA51E, ALA74F, ALA87F, ALA98E, ARG138E, ARG144F, ARG44E, ARG70E, ARG73E, ARG78F, ARG84E, ASN102E, ASN155F, ASN24F, ASN34E, ASN48E, ASN66E, ASP140F, ASP141F, ASP156F, ASP165F, ASP166F, ASP16E, ASP53E, ASP86F, CYS104E, CYS38F, CYS99E, GLN135E, GLN138F, GLN139F, GLN19E, GLN28F, GLN47E, GLN55E, GLU100F, GLU106E, GLU109E, GLU110E, GLU142F, GLU14E, GLU15E, GLU25E, GLU27E, GLU30E, GLU35F, GLU36E, GLU42E, GLU52E, GLU54E, GLU59E, GLU83F, GLU96E, GLY102F, GLY169F, GLY36F, GLY40F, GLY43F, GLY82F, HIS38E, HIS43E, HIS4F, HIS93E, ILE101F, ILE115E, ILE143F, ILE147F, ILE21E, ILE46F, ILE5F, ILE75F, LEU100E, LEU103E, LEU114E, LEU145F, LEU168F, LEU20E, LEU32E, LEU33E, LEU40E, LEU41E, LEU57E, LEU65E, LEU7F, LEU97E, LYS112E, LYS146F, LYS24E, LYS27F, LYS41F, LYS45E, LYS63E, LYS73F, LYS81F, LYS94E, MET104F, MET1F, MET39E, MET62E, PHE22E, PHE26E, PHE2F, PHE31F, PHE44F, PHE61E, PHE71E, PHE77F, PHE80F, PHE95E, PRO103F, PRO105E, PRO116E, PRO20F, PRO23E, PRO79F, SER105F, SER111E, SER18E, SER58E, SER6F, THR107E, THR150F, THR28E, THR31E, THR32F, THR37F, THR39F, THR49F, THR64E, THR68E, THR90F, THR99F, TYR167F, TYR3F, TYR42F, TYR67E, VAL171F, VAL34F, VAL37E, VAL45F, VAL48F, VAL60E, VAL76F, VAL84F, VAL85F, VAL88F, VAL89F
• G-H: ALA101G, ALA108G, ALA113G, ALA17G, ALA29G, ALA47H, ALA51G, ALA74H, ALA87H, ALA98G, ARG138G, ARG144H, ARG44G, ARG70G, ARG73G, ARG78H, ARG84G, ASN102G, ASN155H, ASN24H, ASN34G, ASN48G, ASN66G, ASP140H, ASP141H, ASP156H, ASP165H, ASP166H, ASP16G, ASP53G, ASP86H, CYS104G, CYS38H, CYS99G, GLN135G, GLN138H, GLN139H, GLN19G, GLN28H, GLN47G, GLN55G, GLU100H, GLU106G, GLU109G, GLU110G, GLU142H, GLU14G, GLU15G, GLU25G, GLU27G, GLU30G, GLU35H, GLU36G, GLU42G, GLU52G, GLU54G, GLU59G, GLU83H, GLU96G, GLY102H, GLY169H, GLY36H, GLY40H, GLY43H, GLY82H, HIS38G, HIS43G, HIS4H, HIS93G, ILE101H, ILE115G, ILE143H, ILE147H, ILE21G, ILE46H, ILE5H, ILE75H, LEU100G, LEU103G, LEU114G, LEU145H, LEU168H, LEU20G, LEU32G, LEU33G, LEU40G, LEU41G, LEU57G, LEU65G, LEU7H, LEU97G, LYS112G, LYS146H, LYS24G, LYS27H, LYS41H, LYS45G, LYS63G, LYS73H, LYS81H, LYS94G, MET104H, MET1H, MET39G, MET62G, PHE22G, PHE26G, PHE2H, PHE31H, PHE44H, PHE61G, PHE71G, PHE77H, PHE80H, PHE95G, PRO103H, PRO105G, PRO116G, PRO20H, PRO23G, PRO79H, SER105H, SER111G, SER18G, SER58G, SER6H, THR107G, THR150H, THR28G, THR31G, THR32H, THR37H, THR39H, THR49H, THR64G, THR68G, THR90H, THR99H, TYR167H, TYR3H, TYR42H, TYR67G, VAL171H, VAL34H, VAL37G, VAL45H, VAL48H, VAL60G, VAL76H, VAL84H, VAL85H, VAL88H, VAL89H