2BBA

crystal structure and thermodynamic characterization of the ephb4 receptor in complex with an ephrin-b2 antagonist peptide reveals the determinants for receptor specificity.

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-P
  • Int. Res.: 67
  • Norm. En. per Res.: -3.7876
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-P	-14.0645	-38.0661	-201.64	-253.7706	67	4	8	8090	2	5	4

Interface residues

• A-P: ALA103A, ALA153A, ALA155A, ALA183A, ALA186A, ALA261P, ALA263P, ARG102A, ARG148A, ARG150A, ARG262P, ASN160A, ASN251P, ASN257P, ASP49A, ASP62A, CYS184A, CYS61A, GLN41A, GLN52A, GLN64A, GLU154A, GLU43A, GLU44A, GLU50A, GLU59A, GLU96A, GLY152A, GLY157A, GLY258P, GLY40A, GLY47A, HIS145A, ILE260P, LEU100A, LEU146A, LEU187A, LEU188A, LEU253P, LEU45A, LEU48A, LEU95A, LYS149A, LYS158A, MET185A, MET94A, PHE254P, PHE92A, PRO101A, PRO151A, PRO256P, PRO259P, SER255P, SER46A, SER99A, THR147A, THR156A, THR57A, THR93A, TRP264P, TRP42A, TYR252P, TYR58A, VAL159A, VAL55A, VAL60A, VAL63A