2BAP

crystal structure of the n-terminal mdia1 armadillo repeat region and dimerisation domain in complex with the mdia1 autoregulatory domain (dad)

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 67
  • Norm. En. per Res.: -3.2702
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
B-A	0.0	-13.7105	-101.654	-115.3645	61	4	1	4152	0	10	9
B-D	-26.1368	-13.7881	-179.181	-219.1059	67	11	7	7613	1	7	3
A-C	-19.592	-1.4799	-161.001	-182.0729	68	9	6	6967	0	7	3

Interface residues

• B-A: ALA136A, ALA136B, ARG148B, ARG160A, ARG160B, ARG203A, ARG203B, ARG210A, ARG210B, ASN164B, ASN165A, ASN165B, ASN166A, ASN166B, ASP149A, ASP149B, CYS155A, CYS155B, GLN141A, GLN141B, GLU142A, GLU142B, GLU157A, GLU157B, GLU207A, GLU207B, HIS151A, HIS151B, LEU147B, LEU152A, LEU152B, LEU153A, LEU153B, LEU156A, LEU156B, LEU159A, LEU159B, LEU163A, LEU163B, MET137A, MET137B, MET138A, MET138B, MET150A, MET150B, PRO167A, PRO167B, SER135A, SER135B, SER154A, SER154B, SER158A, SER158B, SER162A, SER162B, TRP170A, TRP170B, TYR139A, TYR139B, VAL161A, VAL161B
• B-D: ALA1188D, ALA1193D, ALA1194D, ALA214B, ALA251B, ALA256B, ALA300B, ALA311B, ASN164B, ASN217B, ASN218B, ASN310B, ASN346B, ASP1183D, ASP249B, ASP348B, CYS258B, CYS354B, GLN1190D, GLN307B, GLN352B, GLN359B, GLU1187D, GLU347B, GLU358B, GLY1180D, GLY1192D, GLY221B, GLY304B, ILE222B, ILE248B, ILE259B, ILE309B, ILE313B, LEU1185D, LEU1186D, LEU1189D, LEU212B, LEU253B, LEU254B, LEU257B, LEU260B, LEU306B, LEU308B, LEU312B, LYS213B, LYS219B, LYS252B, LYS350B, MET1182D, MET216B, MET349B, PHE1195D, PHE215B, PHE220B, PHE356B, PRO261B, PRO315B, SER1184D, SER1191D, SER255B, THR314B, VAL1181D, VAL168B, VAL303B, VAL351B, VAL355B
• A-C: ALA1188C, ALA1193C, ALA1194C, ALA214A, ALA250A, ALA251A, ALA256A, ALA300A, ALA311A, ASN164A, ASN217A, ASN218A, ASN310A, ASN346A, ASP1183C, ASP249A, ASP348A, CYS258A, CYS354A, GLN1190C, GLN307A, GLN352A, GLN359A, GLU1187C, GLU347A, GLU358A, GLY1180C, GLY1192C, GLY221A, GLY304A, ILE222A, ILE248A, ILE259A, ILE309A, ILE313A, LEU1185C, LEU1186C, LEU1189C, LEU212A, LEU253A, LEU254A, LEU257A, LEU260A, LEU306A, LEU308A, LEU312A, LYS213A, LYS219A, LYS252A, LYS350A, MET1182C, MET216A, MET349A, PHE1195C, PHE215A, PHE220A, PHE356A, PRO261A, PRO315A, SER1184C, SER1191C, SER255A, THR314A, VAL1181C, VAL168A, VAL303A, VAL351A, VAL355A