2B43

crystal structure of the norwalk virus rna dependent rna polymerase from strain hu/nlv/dresden174/1997/ge

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 73
  • Norm. En. per Res.: -3.0016
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-3.1111	-3.1111	10	0	0	185	0	2	1
A-C	-46.4962	74.4084	-212.184	-184.2717	121	17	0	7499	0	36	36
A-D	-8.7821	-39.3739	-165.851	-214.0069	74	3	2	6306	5	29	29
B-C	-13.5027	-34.9693	-170.644	-219.116	73	4	2	6340	5	29	29
B-D	-34.686	79.1773	-214.953	-170.4618	120	8	0	7536	0	31	36
C-D	0.0	0.0	-2.6926	-2.6926	10	0	0	177	0	2	1

Interface residues

• A-B: ARG483A, ARG483B, ASP489A, ASP489B, LEU490A, LEU490B, SER491A, SER491B, THR492A, THR492B
• A-C: ALA111A, ALA111C, ALA500A, ALA500C, ARG393A, ARG393C, ARG483A, ARG483C, ARG486A, ARG486C, ARG497A, ARG497C, ASN128C, ASN132A, ASN132C, ASN220A, ASN220C, ASN222A, ASN222C, ASN498A, ASN498C, ASN505A, ASN505C, ASP204C, ASP224A, ASP224C, ASP472A, ASP472C, ASP489A, ASP489C, ASP496A, ASP496C, GLN108A, GLN108C, GLU102A, GLU102C, GLU134A, GLU134C, GLU223A, GLU223C, GLU446A, GLU446C, GLU468A, GLU494A, GLU494C, GLU506A, GLU506C, GLY133A, GLY133C, GLY218A, GLY218C, GLY445A, GLY445C, GLY469A, GLY469C, GLY470A, GLY470C, GLY495A, GLY495C, HIS433A, HIS433C, ILE431A, ILE431C, LEU449A, LEU449C, LEU490A, LEU490C, LEU499A, LEU499C, LYS115C, LYS467A, MET219A, MET219C, MET221A, MET221C, MET430A, MET430C, MET471A, MET471C, MET481A, MET481C, MET485A, MET485C, PHE482A, PHE482C, PHE487A, PHE487C, PHE503A, PHE503C, PRO421A, PRO421C, PRO432A, PRO432C, PRO501A, PRO501C, SER105A, SER105C, SER135C, SER434A, SER434C, SER442A, SER442C, SER488A, SER488C, SER491A, SER491C, SER502A, SER502C, THR107A, THR107C, THR492A, THR492C, TRP104C, TRP131A, TRP131C, TRP484A, TRP484C, TRP493A, TRP493C, VAL504A, VAL504C
• A-D: ALA400A, ALA400D, ALA447A, ALA447D, ALA448A, ALA448D, ALA453A, ALA453D, ARG231D, ARG234A, ARG234D, ARG397A, ARG397D, ARG477A, ARG477D, ARG483A, ARG483D, ARG486A, ARG486D, ASN386D, ASP398A, ASP398D, ASP489A, ASP489D, GLN478A, GLN478D, GLU230A, GLU230D, GLU479A, GLU479D, GLY401A, GLY401D, GLY451A, GLY451D, HIS450A, HIS450D, ILE227A, ILE227D, LEU449A, LEU449D, LYS405A, LYS405D, MET481A, MET481D, PHE403A, PHE403D, PHE482A, PHE482D, PHE487A, PHE487D, PRO226A, PRO226D, PRO399A, PRO399D, PRO452A, PRO452D, PRO480A, PRO480D, SER233A, SER233D, SER456A, SER488A, SER488D, SER491A, SER491D, THR396A, THR396D, THR492A, THR492D, TRP402A, TRP402D, TRP484A, TYR455A, TYR455D
• B-C: ALA400B, ALA400C, ALA447B, ALA447C, ALA448B, ALA448C, ALA453B, ALA453C, ARG231C, ARG234B, ARG234C, ARG397B, ARG397C, ARG477B, ARG477C, ARG483B, ARG483C, ARG486B, ARG486C, ASN386C, ASP398B, ASP398C, ASP489B, ASP489C, GLN478B, GLN478C, GLU230B, GLU230C, GLU479B, GLU479C, GLY401B, GLY401C, GLY451B, GLY451C, HIS450B, HIS450C, ILE227B, LEU449B, LEU449C, LYS405B, LYS405C, MET481B, MET481C, PHE403B, PHE403C, PHE482B, PHE482C, PHE487B, PHE487C, PRO226B, PRO226C, PRO399B, PRO399C, PRO452B, PRO452C, PRO480B, PRO480C, SER233B, SER233C, SER456B, SER456C, SER488B, SER488C, SER491B, SER491C, THR396B, THR396C, THR492B, THR492C, TRP402B, TRP402C, TYR455B, TYR455C
• B-D: ALA111B, ALA111D, ALA500B, ALA500D, ARG393B, ARG393D, ARG483B, ARG483D, ARG486B, ARG486D, ARG497B, ARG497D, ASN132B, ASN132D, ASN220B, ASN220D, ASN222B, ASN222D, ASN498B, ASN498D, ASN505B, ASP204B, ASP204D, ASP224B, ASP224D, ASP472B, ASP472D, ASP489B, ASP489D, ASP496B, ASP496D, GLN108B, GLN108D, GLU102B, GLU102D, GLU134B, GLU134D, GLU223B, GLU223D, GLU446B, GLU446D, GLU468B, GLU494B, GLU494D, GLU506B, GLU506D, GLY133B, GLY133D, GLY218B, GLY218D, GLY445B, GLY445D, GLY469B, GLY469D, GLY470B, GLY470D, GLY495B, GLY495D, HIS433B, HIS433D, ILE431B, ILE431D, LEU449B, LEU449D, LEU490B, LEU490D, LEU499B, LEU499D, LYS115B, MET219B, MET219D, MET221B, MET221D, MET430B, MET430D, MET471B, MET471D, MET481B, MET481D, MET485B, MET485D, PHE482B, PHE482D, PHE487B, PHE487D, PHE503B, PHE503D, PRO421B, PRO432B, PRO432D, PRO501B, PRO501D, SER105B, SER105D, SER135B, SER135D, SER434B, SER434D, SER442B, SER442D, SER488B, SER488D, SER491B, SER491D, SER502B, SER502D, THR107B, THR107D, THR429B, THR492B, THR492D, TRP104D, TRP131B, TRP131D, TRP484B, TRP484D, TRP493B, TRP493D, VAL504B, VAL504D
• C-D: ARG483C, ARG483D, ASP489C, ASP489D, LEU490C, LEU490D, SER491C, SER491D, THR492C, THR492D