2B2A

crystal structure of the ten domain of the telomerase reverse transcriptase

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 69
  • Norm. En. per Res.: -4.5117
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-80.3774	-21.6912	-209.24	-311.3086	69	13	5	8199	0	13	12
A-C	-7.6788	0.0	-45.2779	-52.9567	37	4	0	2067	0	9	4
B-C	-62.4052	-3.2914	-154.447	-220.1435	64	13	2	5841	0	8	6

Interface residues

• A-B: ALA29B, ALA42B, ALA66B, ARG16A, ASN190A, ASN191A, ASN35B, ASN70B, ASN74B, ASP19A, GLN181A, GLN184A, GLN26A, GLN26B, GLN48B, GLN69B, GLU18A, GLU18B, GLU38B, GLU44B, GLU68B, GLU73B, ILE27A, ILE27B, ILE64B, ILE65B, LEU20A, LEU21B, LEU24B, LEU30B, LEU36B, LEU40B, LEU41B, LEU71B, LYS17B, LYS183A, LYS185A, LYS186A, LYS189A, LYS25A, LYS25B, LYS31B, LYS76B, PHE178A, PHE39B, SER179A, SER28A, SER28B, SER34B, SER67B, THR15A, THR22A, THR22B, THR43B, THR61B, THR62B, THR63B, TRP187A, TYR166B, TYR188A, TYR32B, TYR37B, TYR75B, VAL180A, VAL182A, VAL23A, VAL23B, VAL33B, VAL72B
• A-C: ARG16A, ARG16C, ASN164A, ASN164C, ASN175C, ASP19A, ASP19C, ASP53A, CYS173C, GLN12C, GLN163A, GLN168C, GLN176C, GLN55A, GLU162A, GLU18A, GLY165A, GLY165C, ILE110C, ILE27C, LEU14A, LEU14C, LEU167A, LEU174C, LEU20C, LYS160A, LYS17A, LYS185C, MET13A, MET13C, PHE158C, THR15A, THR15C, TYR166A, TYR166C, VAL161A, VAL23C
• B-C: ALA29B, ALA29C, ALA42C, ALA66C, ARG16C, ASN164C, ASN175B, ASN190B, ASN191B, ASN35C, ASN70C, CYS173B, GLN163C, GLN176B, GLN26B, GLN26C, GLN69B, GLN69C, GLU162C, GLU18C, GLU38C, GLU68B, GLU68C, GLY165C, ILE27B, ILE27C, ILE64C, ILE65C, LEU14C, LEU174B, LEU21C, LEU24C, LEU30B, LEU30C, LEU36C, LEU41C, LEU71C, LYS17C, LYS186B, LYS189B, LYS25B, LYS25C, LYS31C, MET13C, PHE39C, SER28B, SER28C, SER34C, SER67C, THR22C, THR61C, THR62C, THR63C, TRP187B, TYR166C, TYR177B, TYR188B, TYR32C, TYR37C, VAL161C, VAL172B, VAL23C, VAL33C, VAL72C