2AZM

crystal structure of the mdc1 brct repeat in complex with the histone tail of gamma-h2ax

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 29
  • Norm. En. per Res.: -3.916
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-25.8591	-14.5442	-102.669	-143.0723	48	5	1	3991	0	15	15
A-C	-26.079	-13.6489	-73.8375	-113.5654	29	2	1	2365	0	4	4
B-D	-20.8597	-19.5659	-68.6213	-109.0468	29	1	1	2327	1	4	4

Interface residues

• A-B: ALA1903B, ALA1908B, ALA2078A, ARG1904B, ARG1907B, ARG1957B, ARG2037A, ARG2054A, ASP1902B, ASP1929B, ASP1951B, GLN1955B, GLN2036A, GLU1906B, GLU2077A, GLY1905B, GLY2056A, HIS1954B, ILE2051A, LEU1950B, LEU1953B, LEU2053A, LEU2057A, LEU2059A, LEU2060A, LYS1958B, LYS2034A, LYS2075A, PHE1897B, PHE2079A, PRO2035A, PRO2052A, PRO2058A, PRO2076A, SER1949B, SER1956B, SER2032A, SER2050A, TYR1968B, TYR1999A, TYR2033A, VAL1900B, VAL1901B, VAL1927B, VAL2038A, VAL2039A, VAL2055A, VAL2080A
• A-C: ALA138C, ARG1930A, ARG1932A, ARG1933A, GLN140C, GLN1975A, GLN2008A, GLN2013A, GLU141C, GLU2063A, GLY1899A, ILE1931A, ILE2017A, LEU1938A, LEU2066A, LEU2070A, LYS1936A, PHE1937A, PHE1979A, PRO2009A, PRO2010A, PRO2062A, THR1898A, THR1934A, TYR142C, VAL1900A, VAL1901A, VAL1935A, VAL2007A
• B-D: ALA138D, ARG1930B, ARG1932B, ARG1933B, GLN140D, GLN1975B, GLN2008B, GLN2013B, GLU141D, GLU2063B, GLY1899B, ILE1931B, ILE2017B, LEU1938B, LEU2066B, LEU2070B, LYS1936B, PHE1937B, PHE1979B, PRO2009B, PRO2010B, PRO2062B, THR1898B, THR1934B, TYR142D, VAL1900B, VAL1901B, VAL1935B, VAL2007B