2AW5

crystal structure of a human malic enzyme

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 204
  • Norm. En. per Res.: -3.4468
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	3.7614	-45.517	-41.7556	57	2	0	2234	1	23	18
B-C	-119.963	-64.183	-518.994	-703.14	204	23	9	22717	8	54	57

Interface residues

• A-B: ALA381A, ALA385A, ALA413A, ALA417A, ARG286B, ARG400B, ARG427B, ARG71A, ASN290B, ASN398B, ASN443B, ASN66A, ASP294B, ASP437A, ASP491B, ASP68A, ASP70A, CYS415A, CYS420A, GLN111A, GLN389A, GLN419A, GLN445B, GLU388A, GLU399B, GLU414A, GLU418A, GLU495B, GLY383A, GLY384A, GLY444B, ILE100A, ILE287B, ILE382A, LEU159A, LEU285B, LEU441B, LEU494B, LEU65A, LYS289B, LYS291B, LYS412A, LYS492B, PHE386A, PHE436A, PHE69A, PRO409A, PRO442B, SER387A, SER411A, SER416A, SER67A, THR288B, THR410A, THR440B, THR446B, VAL439A
• B-C: ALA139B, ALA139C, ALA29B, ALA29C, ARG118B, ARG118C, ARG121B, ARG121C, ARG130B, ARG20B, ARG20C, ARG212B, ARG212C, ARG35B, ARG35C, ARG57B, ARG57C, ARG81B, ARG81C, ASN138B, ASN138C, ASN165B, ASN165C, ASN21B, ASN21C, ASN25B, ASN25C, ASN39B, ASN39C, ASN49B, ASN49C, ASN61B, ASN61C, ASN66B, ASN66C, ASN82B, ASP129B, ASP129C, ASP194B, ASP194C, ASP205B, ASP205C, ASP27B, ASP27C, ASP70B, ASP70C, ASP77B, ASP77C, ASP80B, ASP80C, CYS164B, CYS164C, GLN112B, GLN112C, GLN213C, GLN36B, GLN36C, GLN54B, GLN54C, GLN79B, GLN79C, GLU142B, GLU142C, GLU52B, GLU52C, GLU63B, GLU83B, GLU83C, GLY122B, GLY122C, GLY15B, GLY15C, GLY196B, GLY196C, GLY210B, GLY210C, GLY42B, GLY42C, HIS128B, HIS128C, HIS132B, HIS132C, HIS23B, HIS23C, HIS41B, HIS41C, HIS64B, HIS64C, ILE125B, ILE125C, ILE127B, ILE127C, ILE133B, ILE133C, ILE192B, ILE192C, ILE209B, ILE209C, ILE40B, ILE40C, ILE53B, ILE53C, LEU115B, LEU115C, LEU123B, LEU123C, LEU137B, LEU137C, LEU17B, LEU17C, LEU189B, LEU189C, LEU18B, LEU18C, LEU193C, LEU207B, LEU207C, LEU211B, LEU211C, LEU28B, LEU28C, LEU32C, LEU38B, LEU38C, LEU43B, LEU43C, LEU44B, LEU44C, LEU56B, LEU56C, LEU65B, LEU65C, LEU73B, LEU73C, LEU74B, LEU74C, LEU78B, LEU78C, LEU85B, LYS119B, LYS119C, LYS235B, LYS60B, LYS60C, MET167B, MET167C, PHE117B, PHE117C, PHE124B, PHE124C, PHE30B, PHE30C, PHE48B, PHE48C, PHE62B, PHE62C, PHE69B, PHE69C, PRO120B, PRO120C, PRO141B, PRO141C, PRO206B, PRO206C, PRO22B, PRO22C, PRO45B, PRO45C, PRO46B, PRO46C, SER114B, SER114C, SER135B, SER135C, SER47B, SER47C, SER67B, SER67C, THR126B, THR126C, THR19B, THR19C, TRP140B, TRP140C, TYR113B, TYR113C, TYR16B, TYR16C, TYR208B, TYR208C, VAL116B, VAL116C, VAL136B, VAL136C, VAL191B, VAL191C, VAL195B, VAL195C, VAL55B, VAL55C, VAL58B, VAL58C, VAL59B, VAL59C