2AW2

crystal structure of the human btla-hvem complex

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: X-Y
  • Int. Res.: 79
  • Norm. En. per Res.: -5.8583
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-130.5414	-66.1967	-261.038	-457.7761	83	17	3	10105	2	27	16
A-X	-6.5668	-28.2119	-60.1586	-94.9372	60	1	0	3205	0	27	26
A-Y	0.0	30.089	-33.2088	-3.1198	28	1	2	1510	0	7	9
B-X	0.0	28.5442	-37.7515	-9.2073	28	1	2	1559	1	7	8
B-Y	0.0	0.0	-0.6006	-0.6006	2	0	0	87	0	0	0
X-Y	-123.8527	-79.871	-259.08	-462.8037	79	12	3	10146	4	27	17

Interface residues

• A-B: ALA117A, ALA28B, ALA47B, ARG114A, ARG24B, ARG42A, ARG75B, ASN118A, ASN122A, ASN50B, ASN75A, ASP35A, ASP7B, CYS115A, CYS15B, CYS16B, CYS19B, CYS29B, CYS37B, CYS4B, CYS72A, CYS79A, GLN120A, GLN37A, GLN43A, GLU125A, GLU14B, GLU27B, GLU31B, GLU38B, GLU6B, GLU8B, GLY111A, GLY12B, GLY22B, GLY30B, GLY34B, GLY76A, HIS127A, HIS48B, ILE124A, ILE40A, ILE95A, LEU123A, LEU32B, LEU38A, LEU49B, LEU74A, LYS18B, LYS26B, LYS41A, LYS5B, LYS81A, PHE119A, PRO10B, PRO17B, PRO21B, PRO39B, PRO59A, SER112A, SER116A, SER121A, SER126A, SER128A, SER13B, SER20B, SER3B, SER44A, THR129A, THR130A, THR33B, THR35B, THR77A, THR78A, TYR113A, TYR132A, TYR23B, TYR39A, TYR9B, VAL11B, VAL25B, VAL36A, VAL36B
• A-X: ARG42A, ARG42X, ASN94A, ASN94X, ASP35A, ASP35X, CYS58A, CYS58X, GLN37X, GLN43A, GLN43X, GLU45A, GLU45X, GLU55A, GLU55X, GLU57A, GLU57X, GLU92A, GLU92X, HIS127A, HIS127X, HIS46A, HIS46X, ILE40A, ILE40X, ILE48A, ILE48X, ILE95A, ILE95X, ILE99A, ILE99X, LEU100X, LEU56A, LEU56X, LYS41A, LYS41X, LYS61A, LYS61X, LYS90A, LYS90X, PHE54A, PHE54X, PHE97A, PHE97X, PRO59A, PRO59X, SER44A, SER44X, SER47A, SER47X, THR129A, THR129X, THR130A, THR130X, TRP71A, TRP71X, TYR132A, TYR132X, TYR39A, TYR39X
• A-Y: ASN94A, CYS29Y, CYS58A, GLU14Y, GLU27Y, GLU31Y, GLU55A, GLU57A, GLU92A, GLY30Y, HIS46A, ILE40A, ILE95A, ILE99A, LEU32Y, LEU38A, LEU56A, LYS41A, LYS61A, LYS90A, LYS93A, PHE97A, PRO59A, SER13Y, SER96A, THR33Y, TYR39A, VAL60A
• B-X: ASN94X, CYS29B, CYS58X, GLU14B, GLU27B, GLU31B, GLU55X, GLU57X, GLU92X, GLY30B, HIS46X, ILE40X, ILE95X, ILE99X, LEU32B, LEU38X, LEU56X, LYS41X, LYS61X, LYS90X, LYS93X, PHE97X, PRO59X, SER13B, SER96X, THR33B, TYR39X, VAL60X
• B-Y: LEU32B, LEU32Y
• X-Y: ALA117X, ALA28Y, ALA47Y, ARG114X, ARG24Y, ARG42X, ARG75Y, ASN118X, ASN122X, ASN50Y, ASN75X, ASP35X, ASP7Y, CYS115X, CYS15Y, CYS16Y, CYS19Y, CYS29Y, CYS37Y, CYS4Y, CYS72X, CYS79X, GLN120X, GLN37X, GLN43X, GLU125X, GLU14Y, GLU27Y, GLU31Y, GLU38Y, GLU6Y, GLU8Y, GLY12Y, GLY22Y, GLY30Y, GLY34Y, GLY76X, HIS127X, HIS48Y, ILE124X, ILE40X, ILE95X, LEU123X, LEU32Y, LEU38X, LEU49Y, LEU74X, LYS18Y, LYS26Y, LYS41X, LYS5Y, PHE119X, PRO10Y, PRO17Y, PRO21Y, PRO39Y, PRO59X, SER112X, SER116X, SER121X, SER126X, SER128X, SER13Y, SER20Y, SER3Y, SER44X, THR130X, THR33Y, THR35Y, THR77X, THR78X, TYR132X, TYR23Y, TYR39X, TYR9Y, VAL11Y, VAL25Y, VAL36X, VAL36Y