2AST

crystal structure of skp1-skp2-cks1 in complex with a p27 peptide

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 115
  • Norm. En. per Res.: -3.6499
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-38.5839	-27.0405	-354.112	-419.7365	115	12	11	15220	0	30	21
B-C	-46.4952	4.1936	-251.281	-293.5826	102	11	0	10071	5	28	37
B-D	-16.4155	-18.8391	-41.6596	-76.9142	22	2	2	1264	1	3	2
C-D	-6.2843	-21.1207	-60.2289	-87.6339	28	2	0	2022	2	5	6

Interface residues

• A-B: ALA1106A, ALA1107A, ALA1124A, ALA2131B, ARG1136A, ARG1154A, ARG2126B, ARG2154B, ARG2415B, ASN1108A, ASN1125A, ASN1140A, ASN1143A, ASN1157A, ASN2146B, ASP1083A, ASP1084A, ASP1096A, ASP1111A, ASP1117A, ASP1144A, ASP2098B, ASP2141B, CYS1120A, CYS1160A, CYS2111B, CYS2113B, CYS2124B, GLN1097A, GLN1152A, GLN1158A, GLN2158B, GLU1102A, GLU1133A, GLU1134A, GLU1149A, GLU1150A, GLU1156A, GLU2103B, GLU2116B, GLY1098A, GLY1129A, GLY2107B, GLY2122B, HIS2148B, ILE1085A, ILE1104A, ILE1127A, ILE1135A, ILE1141A, ILE2108B, LEU1100A, LEU1103A, LEU1105A, LEU1116A, LEU2100B, LEU2104B, LEU2105B, LEU2106B, LEU2112B, LEU2114B, LEU2117B, LEU2118B, LEU2140B, LEU2142B, LEU2147B, LEU2155B, LEU2416B, LEU2418B, LYS1121A, LYS1128A, LYS1130A, LYS1137A, LYS1142A, LYS1155A, LYS2119B, LYS2125B, LYS2145B, LYS2413B, MET1126A, PHE1101A, PHE1139A, PHE1145A, PHE2109B, PHE2163B, PRO1132A, PRO2101B, PRO2115B, SER2096B, SER2099B, SER2110B, SER2121B, SER2132B, THR1082A, THR1099A, THR1119A, THR1122A, THR1131A, THR1138A, THR1146A, THR2152B, THR2417B, TRP1159A, TRP2097B, TRP2127B, TRP2137B, TYR1109A, TYR2128B, VAL1118A, VAL1123A, VAL1153A, VAL2095B, VAL2120B, VAL2123B, VAL2151B
• B-C: ALA3029C, ARG2164B, ARG2167B, ARG2217B, ARG2294B, ARG2344B, ARG2398B, ARG3044C, ARG3070C, ASN2190B, ASN2236B, ASN2262B, ASN2289B, ASN2389B, ASN2403B, ASN2406B, ASN3045C, ASP2187B, ASP2268B, ASP2316B, ASP2319B, CYS2390B, GLN2366B, GLN2407B, GLN3049C, GLN3050C, GLN3052C, GLU2214B, GLU2408B, GLU3040C, GLU3042C, GLU3061C, GLY2144B, GLY2215B, GLY2239B, GLY2292B, GLY2369B, GLY2402B, GLY3047C, GLY3053C, HIS2392B, HIS3036C, HIS3056C, ILE2396B, ILE2401B, ILE3028C, ILE3059C, LEU2216B, LEU2317B, LEU3031C, LEU3037C, LEU3046C, LYS2295B, LYS2404B, LYS2405B, LYS3026C, LYS3030C, LYS3034C, MET3038C, MET3058C, PHE2169B, PHE2267B, PHE2368B, PHE2393B, PHE3017C, PRO2166B, PRO2399B, PRO3033C, PRO3064C, PRO3072C, SER2189B, SER2191B, SER2212B, SER2238B, SER2241B, SER2264B, SER2291B, SER2318B, SER2320B, SER2341B, SER2343B, SER2391B, SER3039C, SER3041C, SER3051C, THR2143B, THR2394B, THR2395B, THR2400B, THR3035C, TRP2265B, TRP3043C, TRP3054C, TYR2293B, TYR2346B, TYR3057C, VAL2192B, VAL2321B, VAL2367B, VAL3032C, VAL3048C, VAL3055C
• B-D: ALA4181D, ARG2294B, ARG2344B, ASP2319B, ASP2347B, CYS2345B, GLN4186D, GLU4185D, GLY2369B, GLY4182D, ILE2348B, ILE2370B, LYS2295B, LYS2324B, MET2322B, PRO2372B, SER4183D, TRP2265B, TYR2346B, VAL2321B, VAL2371B, VAL4184D
• C-D: ALA4181D, ARG3020C, ARG3044C, ARG3071C, ASP3010C, GLN3049C, GLN3050C, GLN3052C, GLN4186D, GLU3040C, GLU4185D, GLY3047C, GLY3053C, ILE3006C, LYS3011C, LYS4189D, LYS4190D, PRO4188D, SER3009C, SER3051C, SER4183D, TRP3043C, TRP3054C, TYR3007C, TYR3008C, VAL3022C, VAL3048C, VAL4184D