2AS5

structure of the dna binding domains of nfat and foxp2 bound specifically to dna.

• Total interactions analyzed: 28
• Total true interactions: 5
• Strongest Interaction:
  • Chains: N-F
  • Int. Res.: 50
  • Norm. En. per Res.: -2.0814
• Hub Node: N(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
N-M	0.0	9.1547	-74.4486	-65.2939	70	6	1	4701	0	23	25
N-F	-23.5947	-41.5214	-38.9563	-104.0725	50	2	0	2636	3	19	20
N-G	0.0	21.2567	-17.4665	3.7902	15	5	0	844	0	8	4
M-F	0.0	18.6725	-18.174	0.4985	15	4	0	899	0	7	4
M-G	-8.2298	-10.6474	-37.9939	-56.8711	41	0	0	2175	5	16	15

Interface residues

• N-M: ALA392M, ALA392N, ALA472M, ALA472N, ARG522M, ARG522N, ARG529M, ARG529N, ARG547M, ARG547N, ARG556M, ARG556N, ASN495M, ASN495N, ASP525M, ASP525N, GLN475M, GLN475N, GLU398M, GLU398N, GLU425M, GLU425N, GLU532M, GLU532N, GLU552M, GLU552N, GLY494M, GLY494N, GLY531M, GLY531N, GLY555M, GLY555N, ILE492M, ILE492N, ILE526M, ILE526N, ILE557M, ILE557N, LEU394M, LEU394N, LEU397M, LEU397N, LEU401M, LEU401N, LEU519M, LEU519N, LEU521M, LEU521N, LEU528M, LEU528N, LYS497M, LYS497N, LYS530M, LYS530N, PHE473M, PHE473N, PRO395M, PRO395N, PRO396M, PRO396N, PRO400N, SER393M, SER393N, SER554M, SER554N, THR496M, TRP399M, TRP399N, VAL493M, VAL493N
• N-F: ALA524N, ALA571F, ARG466N, ARG536F, ARG537N, ARG564F, ARG665N, ARG667N, ASN523N, ASN528F, ASN539N, ASN567F, ASP464N, ASP522F, ASP534N, ASP617N, GLN524F, GLN669N, GLU465N, GLU527N, GLU529F, GLU532N, GLU566F, GLY536N, GLY570F, GLY618N, ILE535N, LEU525F, LEU527F, LEU528N, LYS469N, LYS530N, LYS538N, LYS549F, LYS569F, LYS614N, LYS664N, PHE473N, PRO670N, SER532F, SER668N, THR462N, THR526F, THR533N, THR535F, THR612N, TYR531F, TYR659N, VAL568F, VAL572F
• N-G: ALA524N, ALA539G, ARG522N, ARG536G, ARG542G, ARG543G, ASP525N, GLU425N, ILE502G, PHE538G, THR426N, THR535G, THR537G, TYR424N, TYR540G
• M-F: ALA524M, ALA539F, ARG522M, ARG536F, ARG542F, ARG543F, ASP525M, GLU425M, ILE502F, PHE538F, THR426M, THR535F, THR537F, TYR424M, TYR540F
• M-G: ALA524M, ALA571G, ARG466M, ARG536G, ARG537M, ARG564G, ARG665M, ARG667M, ASN523M, ASN528G, ASN539M, ASN567G, ASP464M, ASP534M, GLN669M, GLU465M, GLU527M, GLU529G, GLU566G, GLY536M, GLY570G, ILE535M, LEU525G, LEU527G, LEU528M, LYS530M, LYS538M, LYS549G, LYS569G, LYS664M, PHE473M, PRO670M, SER532G, SER668M, THR526G, THR533M, THR535G, TRP548G, TYR531G, VAL568G, VAL572G