2AN5

structure of human pnmt complexed with s-adenosyl- homocysteine and an inhibitor, trans-(1s,2s)-2-amino-1- tetralol

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 59
  • Norm. En. per Res.: 21.8515
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	1289.24	1289.24	59	16	1	4247	0	13	15

Interface residues

• A-B: ALA130A, ALA130B, ARG145A, ARG145B, ARG59A, ARG59B, ASN122A, ASN49A, ASN49B, ASP142A, ASP142B, ASP46A, ASP46B, CYS131A, CYS131B, CYS139A, CYS139B, CYS48A, CYS48B, GLN128A, GLN128B, GLN141A, GLN141B, GLU134A, GLU134B, GLU138A, GLU138B, GLY135A, GLY135B, GLY137A, GLY137B, GLY45A, GLY45B, HIS129A, HIS129B, ILE133A, ILE133B, LEU132A, LEU132B, LEU47A, LEU47B, LYS136A, LYS136B, LYS143A, LYS143B, MET125A, MET125B, PRO42A, PRO42B, PRO50A, PRO50B, PRO55A, PRO55B, SER124A, SER124B, SER127A, SER127B, TRP140A, TRP140B