2AN1

structural genomics, the crystal structure of a putative kinase from salmonella typhimurim lt2

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 142
  • Norm. En. per Res.: -4.1464
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-47.1142	-47.1142	14	0	1	1604	0	0	3
A-C	0.0	2.3171	-156.065	-153.7479	93	5	5	6066	0	21	16
A-D	-119.9891	-9.2027	-509.909	-639.1008	156	16	20	21310	1	13	21
B-C	-132.6363	1.6318	-457.782	-588.7866	142	18	21	19181	0	12	20
B-D	-13.9536	3.6011	-153.277	-163.6295	90	6	7	6361	0	20	17
C-D	-5.6243	0.0	-44.3545	-49.9788	14	2	1	1549	0	0	3

Interface residues

• A-B: ALA218A, ALA218B, ARG219A, ARG219B, HIS214A, HIS214B, LEU216A, LEU216B, PRO213A, PRO213B, SER217A, SER217B, THR215A, THR215B
• A-C: ALA157A, ALA189A, ALA189C, ALA194A, ALA194C, ALA249A, ALA249C, ARG175A, ARG175C, ASN97C, ASP177A, ASP177C, ASP239C, GLN247A, GLN247C, GLU241A, GLU241C, GLY154A, GLY154C, GLY178A, GLY178C, GLY195A, GLY195C, GLY196A, GLY196C, GLY286A, GLY286C, HIS152A, HIS152C, HIS158A, HIS158C, HIS214A, HIS214C, ILE160C, ILE180A, ILE180C, ILE198A, ILE198C, ILE248A, ILE248C, LEU151C, LEU179A, LEU192A, LEU192C, LEU216A, LEU216C, LEU240C, LEU281A, LEU281C, LEU285A, LEU285C, LYS155A, LYS155C, LYS284A, LYS284C, MET159A, MET159C, MET211A, MET211C, PHE100A, PHE100C, PHE212A, PHE212C, PRO153A, PRO153C, PRO210A, PRO210C, PRO213A, PRO213C, SER176A, SER176C, SER191A, SER191C, SER193A, SER193C, SER217A, SER217C, SER243A, SER243C, SER246C, THR188A, THR188C, THR215A, THR215C, TRP287A, TRP287C, TYR190A, TYR190C, VAL150A, VAL150C, VAL156A, VAL209A, VAL209C
• A-D: ALA171A, ALA171D, ALA194A, ALA194D, ALA205A, ALA205D, ALA218A, ALA218D, ARG175A, ARG175D, ARG219A, ARG219D, ARG232A, ARG232D, ARG236D, ASN224A, ASN224D, ASN279A, ASN279D, ASP167A, ASP167D, ASP204A, ASP204D, GLN174A, GLN174D, GLU161A, GLU161D, GLU163A, GLU163D, GLU168D, GLY195A, GLY195D, GLY196A, GLY196D, GLY286A, GLY286D, HIS214A, HIS214D, HIS235A, HIS235D, ILE160A, ILE160D, ILE166A, ILE166D, ILE198A, ILE198D, ILE206A, ILE206D, ILE223A, ILE223D, ILE229A, LEU192A, LEU192D, LEU199A, LEU199D, LEU203A, LEU203D, LEU208A, LEU208D, LEU216A, LEU216D, LEU221A, LEU221D, LEU231A, LEU231D, LEU240A, LEU240D, LEU281A, LEU281D, LEU285A, LEU285D, LEU291A, LEU291D, LYS284A, LYS284D, LYS289A, LYS289D, LYS290A, LYS290D, MET159A, PHE162A, PHE162D, PHE170A, PHE170D, PHE172A, PHE172D, PHE233A, PHE233D, PHE278A, PHE278D, PHE292A, PHE292D, PRO184A, PRO184D, PRO197A, PRO197D, PRO201A, PRO201D, PRO210A, PRO210D, PRO213D, PRO220A, PRO220D, SER173A, SER173D, SER187A, SER187D, SER191A, SER191D, SER193A, SER193D, SER202A, SER202D, SER217A, SER217D, SER225A, SER225D, SER226A, SER226D, SER227A, SER227D, SER234A, SER234D, SER276A, SER276D, SER282A, SER282D, SER288A, SER288D, THR169A, THR169D, THR188A, THR188D, THR200A, THR200D, THR207A, THR207D, THR215A, THR215D, THR280D, THR283A, THR283D, TRP287A, TRP287D, TYR165A, TYR165D, TYR275A, TYR275D, TYR277A, TYR277D, VAL164A, VAL164D, VAL209A, VAL209D, VAL222A, VAL222D
• B-C: ALA171B, ALA171C, ALA194B, ALA194C, ALA205B, ALA205C, ALA218B, ALA218C, ARG175B, ARG175C, ARG219B, ARG219C, ARG232C, ASN224B, ASN224C, ASN279B, ASN279C, ASP167B, ASP167C, ASP204B, ASP204C, GLN174B, GLN174C, GLU161B, GLU161C, GLU163B, GLU163C, GLU168C, GLY195B, GLY195C, GLY196B, GLY196C, GLY286B, GLY286C, HIS214B, HIS214C, ILE160C, ILE166B, ILE166C, ILE198B, ILE198C, ILE206B, ILE206C, ILE223B, ILE223C, ILE229B, LEU192B, LEU192C, LEU199B, LEU199C, LEU203B, LEU203C, LEU208B, LEU208C, LEU216B, LEU216C, LEU221B, LEU221C, LEU231C, LEU240C, LEU281B, LEU281C, LEU285B, LEU285C, LEU291B, LYS284B, LYS284C, LYS289B, LYS289C, LYS290B, LYS290C, PHE162B, PHE162C, PHE170B, PHE170C, PHE172B, PHE172C, PHE233C, PHE278B, PHE278C, PHE292B, PRO184B, PRO184C, PRO197B, PRO197C, PRO201B, PRO201C, PRO210B, PRO210C, PRO220B, PRO220C, SER173B, SER173C, SER187B, SER187C, SER191B, SER191C, SER193B, SER193C, SER202B, SER202C, SER217B, SER217C, SER225B, SER225C, SER226B, SER226C, SER227B, SER227C, SER234B, SER234C, SER276B, SER276C, SER282B, SER282C, SER288B, SER288C, THR169B, THR169C, THR188B, THR188C, THR200B, THR200C, THR207B, THR207C, THR215B, THR215C, THR283C, TRP287B, TRP287C, TYR165B, TYR165C, TYR275B, TYR275C, TYR277B, TYR277C, VAL164B, VAL164C, VAL209B, VAL209C, VAL222B, VAL222C
• B-D: ALA157B, ALA157D, ALA189B, ALA189D, ALA194B, ALA194D, ALA249B, ALA249D, ARG175B, ARG175D, ASP177B, ASP177D, ASP239B, GLN247B, GLU241B, GLU241D, GLY154B, GLY154D, GLY178B, GLY178D, GLY195B, GLY195D, GLY196B, GLY196D, GLY286B, GLY286D, HIS152B, HIS152D, HIS158B, HIS158D, HIS214B, HIS214D, ILE180B, ILE180D, ILE198B, ILE198D, ILE248D, LEU151B, LEU192B, LEU192D, LEU216B, LEU216D, LEU281B, LEU281D, LEU285B, LEU285D, LYS155B, LYS155D, LYS284B, LYS284D, MET159B, MET159D, MET211B, MET211D, PHE100B, PHE100D, PHE212B, PHE212D, PRO153B, PRO153D, PRO210B, PRO210D, PRO213B, PRO213D, SER176B, SER176D, SER191B, SER191D, SER193B, SER193D, SER217B, SER217D, SER243B, SER243D, SER246B, SER246D, THR188B, THR188D, THR215B, THR215D, TRP287B, TRP287D, TYR190B, TYR190D, VAL150B, VAL150D, VAL156B, VAL156D, VAL209B, VAL209D
• C-D: ALA218C, ALA218D, ARG219C, ARG219D, HIS214C, HIS214D, LEU216C, LEU216D, PRO213C, PRO213D, SER217C, SER217D, THR215C, THR215D