2AJQ

structure of replicative dna polymerase provides insigts into the mechanisms for processivity, frameshifting and editing

• Total interactions analyzed: 28
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 99
  • Norm. En. per Res.: -4.0215
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-77.5329	-8.0683	-312.529	-398.1301	99	20	16	12635	0	15	22
A-F	0.0	-1.0888	-11.0286	-12.1174	33	0	0	774	0	12	20
F-I	-61.3283	0.9077	-343.61	-404.0306	103	30	15	13723	0	14	20

Interface residues

• A-B: ALA105B, ALA29B, ALA322A, ALA324A, ALA39B, ALA67B, ALA87B, ALA88B, ALA93B, ARG278A, ARG288A, ARG318A, ARG73B, ASN106B, ASN63B, ASP104B, ASP316A, ASP61B, CYS275A, CYS32B, CYS35B, GLN266A, GLN98B, GLU101B, GLU30B, GLU319A, GLU330A, GLU348A, GLY262A, GLY295A, GLY296A, GLY323A, GLY33B, GLY65B, GLY71B, GLY74B, GLY92B, GLY97B, HIS276A, HIS331A, ILE289A, ILE297A, ILE38B, ILE41B, ILE60B, ILE72B, ILE75B, LEU103B, LEU283A, LEU315A, LEU78B, LEU79B, LEU94B, LEU99B, LYS100B, LYS268A, LYS285A, LYS290A, LYS344A, LYS345A, LYS36B, LYS69B, LYS90B, MET273A, MET37B, PHE102B, PHE274A, PHE27B, PHE298A, PRO267A, PRO277A, PRO287A, PRO292A, PRO325A, PRO328A, PRO34B, PRO40B, PRO64B, PRO68B, PRO76B, SER263A, SER95B, THR291A, THR317A, THR327A, THR66B, THR77B, THR89B, TRP264A, TRP28B, TRP31B, TYR265A, TYR286A, TYR320A, TYR326A, TYR70B, VAL321A, VAL329A, VAL91B
• A-F: ALA247F, ALA248F, ALA29A, ALA400F, ARG111A, ARG250F, ARG408F, GLU152F, GLU153F, GLU195A, GLU240F, GLU241F, GLU575A, GLY108A, GLY113A, GLY151F, GLY466F, LEU109A, LEU110A, LEU407F, LEU461F, LYS114A, LYS17F, LYS467F, LYS587A, MET107A, SER112A, SER27A, THR28A, TYR243F, TYR24A, TYR26A, VAL244F
• F-I: ALA105I, ALA29I, ALA322F, ALA324F, ALA39I, ALA67I, ALA87I, ALA88I, ALA93I, ARG278F, ARG288F, ARG318F, ARG73I, ASN106I, ASN63I, ASP104I, ASP316F, ASP61I, CYS275F, CYS32I, CYS35I, GLN266F, GLN98I, GLU101I, GLU30I, GLU319F, GLU330F, GLU348F, GLY262F, GLY269F, GLY270F, GLY295F, GLY296F, GLY323F, GLY33I, GLY65I, GLY71I, GLY74I, GLY92I, GLY97I, HIS276F, HIS331F, ILE289F, ILE297F, ILE38I, ILE41I, ILE60I, ILE72I, ILE75I, LEU103I, LEU107I, LEU283F, LEU315F, LEU78I, LEU79I, LEU94I, LEU99I, LYS100I, LYS268F, LYS285F, LYS290F, LYS344F, LYS345F, LYS36I, LYS69I, LYS90I, MET37I, PHE102I, PHE274F, PHE27I, PHE298F, PRO267F, PRO277F, PRO287F, PRO292F, PRO325F, PRO328F, PRO34I, PRO40I, PRO64I, PRO68I, PRO76I, SER263F, SER95I, THR291F, THR317F, THR327F, THR66I, THR77I, THR89I, TRP264F, TRP31I, TYR265F, TYR286F, TYR320F, TYR326F, TYR49I, TYR70I, VAL321F, VAL329F, VAL332F, VAL86I, VAL91I