2AGH

structural basis for cooperative transcription factor binding to the cbp coactivator

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 67
  • Norm. En. per Res.: -4.869
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-54.5804	-91.772	-179.87	-326.2224	67	11	9	7782	6	31	29
B-C	-25.9748	-46.2994	-191.966	-264.2402	62	4	7	8060	2	13	11

Interface residues

• A-B: ALA610B, ALA654B, ARG294A, ARG600B, ARG646B, ARG669B, ASN307A, ASP598B, ASP647B, CB7.222381.66218, CB8.58664-27.44194, CB8.58673-10.72831, GLN312A, GLN597B, GLN609B, GLN661B, GLU292A, GLU297A, GLU299A, GLU306A, GLU308A, GLU593B, GLU636B, GLU655B, GLU665B, GLU666B, GLY311A, HIS594B, HIS602B, HIS605B, HIS651B, ILE295A, ILE611B, ILE657B, ILE660B, LEU298A, LEU300A, LEU301A, LEU302A, LEU309A, LEU599B, LEU603B, LEU607B, LEU652B, LEU653B, LEU672B, LYS291A, LYS291A5, LYS296A, LYS310A, LYS606B, LYS656B, LYS659B, LYS662B, MET303A, PRO613B, SER304A, SER601B, SER670B, THR305A, THR596B, TYR649B, TYR650B, TYR658B, VAL595B, VAL604B, VAL608B
• B-C: ALA610B, ALA619B, ALA630B, ALA632B, ARG623B, ARG624B, ARG668B, ARG669B, ARG671B, ASN627B, ASN843C, ASN856C, ASP616B, ASP622B, ASP638B, ASP841C, ASP848C, ASP851C, GLN661B, GLN861C, GLU626B, GLU655B, GLU663B, GLU665B, GLY842C, ILE611B, ILE657B, ILE660B, ILE844C, ILE849C, LEU620B, LEU628B, LEU652B, LEU664B, LEU672B, LEU845C, LEU854C, LYS634B, LYS656B, LYS659B, LYS667B, LYS855C, MET625B, MET639B, MET850C, MET860C, PHE612B, PHE852C, PRO613B, PRO615B, PRO846C, PRO858C, SER670B, SER847C, SER859C, THR614B, THR857C, TYR631B, VAL608B, VAL629B, VAL635B, VAL853C