2AG5

crystal structure of human dhrs6

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 148
  • Norm. En. per Res.: -5.1534
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-45.6198	36.2628	-367.736	-377.093	142	15	11	15010	2	20	27
A-C	-17.5818	1.1856	-42.7297	-59.1259	26	3	0	1442	0	2	5
A-D	-109.0642	-143.5548	-510.085	-762.704	148	21	20	19977	10	42	31
B-C	-99.5732	-145.2364	-516.775	-761.5846	149	12	20	19845	10	39	31
B-D	-28.2556	0.0	-34.9681	-63.2237	24	2	0	1124	0	2	7
C-D	-53.6047	35.9422	-366.709	-384.3714	139	18	11	14778	1	20	27

Interface residues

• A-B: ALA162A, ALA162B, ALA163A, ALA163B, ALA212A, ALA212B, ALA218A, ALA218B, ALA230A, ALA230B, ARG171A, ARG171B, ARG205A, ARG205B, ARG210A, ARG210B, ARG3A, ARG3B, ASN173A, ASN173B, ASN235A, ASN235B, ASP164A, ASP164B, ASP181A, ASP227A, ASP227B, ASP240A, ASP240B, CYS172A, CYS172B, CYS176A, CYS176B, CYS221A, CYS221B, GLN167A, GLN167B, GLN168A, GLN168B, GLN206A, GLN206B, GLU215A, GLU215B, GLU216A, GLU216B, GLU228A, GLU228B, GLU29A, GLU29B, GLY156A, GLY156B, GLY169A, GLY169B, GLY178A, GLY178B, GLY209A, GLY209B, GLY234A, GLY234B, GLY241A, GLY241B, GLY242A, GLY242B, GLY246A, GLY246B, ILE155A, ILE155B, ILE166A, ILE166B, ILE170A, ILE170B, ILE217A, ILE217B, ILE238A, ILE238B, ILE239A, ILE239B, LEU203A, LEU203B, LEU220A, LEU220B, LEU224A, LEU224B, LEU245A, LEU245B, LYS139A, LYS159A, LYS159B, LYS204A, LYS207A, LYS207B, MET219A, MET219B, PHE165A, PHE165B, PHE202A, PHE202B, PHE211A, PHE211B, PRO177A, PRO177B, PRO236A, PRO236B, SER160A, SER160B, SER226A, SER226B, SER229A, SER229B, SER244A, SER244B, THR158A, THR158B, THR179A, THR179B, THR208A, THR208B, THR213A, THR213B, THR233A, THR233B, TRP243A, TRP243B, TYR223A, TYR223B, TYR231A, TYR231B, VAL134A, VAL134B, VAL138A, VAL138B, VAL161A, VAL161B, VAL175B, VAL180A, VAL180B, VAL222A, VAL222B, VAL232A, VAL232B, VAL237A, VAL237B
• A-C: ARG205C, ASP240C, GLY140A, GLY140C, GLY246A, ILE238C, LEU245A, LEU245C, LYS139A, LYS139C, LYS207A, LYS207C, SER136A, SER136C, SER137A, SER137C, SER244A, SER244C, TRP243C, VAL134C, VAL138A, VAL138C, VAL141A, VAL141C, VAL142A, VAL142C
• A-D: ALA115A, ALA115D, ALA135A, ALA135D, ALA152A, ALA152D, ALA153A, ALA153D, ALA162A, ALA162D, ALA163A, ALA163D, ARG107A, ARG107D, ARG144A, ARG144D, ASN103A, ASN103D, ASN105A, ASN143A, ASN143D, ASN235D, ASP164A, ASP164D, ASP66A, ASP66D, ASP92A, ASP92D, ASP97A, ASP97D, ASP99A, ASP99D, CYS145A, CYS145D, CYS93A, CYS93D, GLN167A, GLN167D, GLN168A, GLU94A, GLU94D, GLU95A, GLU95D, GLY140A, GLY140D, GLY156A, GLY156D, GLY234A, GLY234D, GLY88A, GLY88D, HIS86A, HIS86D, ILE113A, ILE113D, ILE128A, ILE128D, ILE155A, ILE155D, ILE166A, ILE166D, ILE170A, ILE170D, LEU111A, LEU111D, LEU117A, LEU117D, LEU121A, LEU121D, LEU157A, LEU157D, LEU91A, LEU91D, LYS114A, LYS114D, LYS119A, LYS119D, LYS139A, LYS139D, LYS151A, LYS151D, LYS159A, LYS159D, LYS62A, LYS62D, LYS63A, LYS63D, LYS96A, LYS96D, MET102A, MET102D, MET109A, MET109D, MET112A, MET112D, MET120A, PHE100D, PHE116A, PHE116D, PHE165A, PHE165D, PRO118A, PRO118D, PRO236A, PRO236D, SER108A, SER108D, SER136A, SER136D, SER137A, SER137D, SER148A, SER148D, SER160A, SER160D, SER244A, THR149A, THR149D, THR150A, THR150D, THR158A, THR158D, THR89A, THR89D, TRP98A, TRP98D, TYR110A, TYR110D, TYR147A, TYR147D, VAL106A, VAL106D, VAL134A, VAL134D, VAL138A, VAL138D, VAL141A, VAL141D, VAL142A, VAL142D, VAL146A, VAL146D, VAL154A, VAL154D, VAL161A, VAL161D, VAL90A, VAL90D
• B-C: ALA115B, ALA115C, ALA135B, ALA135C, ALA152B, ALA152C, ALA153B, ALA153C, ALA162B, ALA162C, ALA163B, ALA163C, ARG107B, ARG107C, ARG144B, ARG144C, ASN103B, ASN103C, ASN105B, ASN130C, ASN143B, ASN143C, ASP164B, ASP164C, ASP66B, ASP66C, ASP92B, ASP92C, ASP97B, ASP97C, ASP99B, ASP99C, CYS145B, CYS145C, CYS93B, CYS93C, GLN167B, GLN167C, GLN168B, GLU94B, GLU94C, GLU95B, GLU95C, GLY140B, GLY140C, GLY156B, GLY156C, GLY234B, GLY234C, GLY88B, GLY88C, HIS86B, HIS86C, ILE113B, ILE113C, ILE128B, ILE128C, ILE155B, ILE155C, ILE166B, ILE166C, ILE170B, ILE170C, LEU111B, LEU111C, LEU117B, LEU117C, LEU121B, LEU121C, LEU157B, LEU157C, LEU91B, LEU91C, LYS114B, LYS114C, LYS119B, LYS119C, LYS139B, LYS139C, LYS151B, LYS151C, LYS159B, LYS159C, LYS62B, LYS62C, LYS63C, LYS96B, LYS96C, MET102B, MET102C, MET109B, MET109C, MET112B, MET112C, MET120B, PHE100B, PHE100C, PHE116B, PHE116C, PHE165B, PHE165C, PRO118B, PRO118C, PRO236B, PRO236C, SER108B, SER108C, SER132B, SER132C, SER136B, SER136C, SER137B, SER137C, SER148B, SER148C, SER160B, SER160C, THR149B, THR149C, THR150B, THR150C, THR158B, THR158C, THR89B, THR89C, TRP98B, TRP98C, TYR110B, TYR110C, TYR147B, TYR147C, VAL106B, VAL106C, VAL134B, VAL134C, VAL138B, VAL138C, VAL141B, VAL141C, VAL142B, VAL142C, VAL146B, VAL146C, VAL154B, VAL154C, VAL161B, VAL161C, VAL90B, VAL90C
• B-D: GLY140B, GLY140D, GLY246B, LEU245B, LEU245D, LYS139B, LYS139D, LYS207B, LYS207D, SER136B, SER136D, SER137B, SER137D, SER244B, SER244D, TRP243D, VAL134B, VAL134D, VAL138B, VAL138D, VAL141B, VAL141D, VAL142B, VAL142D
• C-D: ALA162C, ALA162D, ALA163C, ALA163D, ALA212C, ALA212D, ALA218C, ALA218D, ALA230C, ALA230D, ARG171C, ARG171D, ARG205C, ARG205D, ARG210C, ARG210D, ARG3C, ARG3D, ASN173C, ASN173D, ASN235C, ASN235D, ASP164C, ASP164D, ASP181C, ASP181D, ASP227C, ASP227D, ASP240C, ASP240D, CYS172C, CYS172D, CYS176C, CYS176D, CYS221C, CYS221D, GLN167C, GLN167D, GLN168C, GLN168D, GLN206C, GLN206D, GLU215C, GLU215D, GLU216C, GLU216D, GLU228C, GLU228D, GLU29C, GLU29D, GLY156C, GLY156D, GLY169C, GLY169D, GLY178C, GLY178D, GLY209C, GLY209D, GLY234C, GLY234D, GLY241C, GLY241D, GLY242C, GLY242D, ILE155C, ILE155D, ILE166C, ILE166D, ILE170C, ILE170D, ILE217C, ILE217D, ILE238C, ILE238D, ILE239C, ILE239D, LEU203C, LEU203D, LEU220C, LEU220D, LEU224C, LEU224D, LEU245C, LEU245D, LYS159C, LYS159D, LYS207C, LYS207D, MET219C, MET219D, PHE165C, PHE165D, PHE202C, PHE202D, PHE211C, PHE211D, PRO177C, PRO177D, PRO236C, PRO236D, SER160C, SER160D, SER226C, SER226D, SER229C, SER229D, SER244C, SER244D, THR158C, THR158D, THR179C, THR179D, THR208C, THR208D, THR213C, THR213D, THR233C, THR233D, TRP243C, TRP243D, TYR223C, TYR223D, TYR231C, TYR231D, VAL134C, VAL134D, VAL138C, VAL138D, VAL161C, VAL161D, VAL175C, VAL180C, VAL180D, VAL222C, VAL222D, VAL232C, VAL232D, VAL237C, VAL237D