2A1S

crystal structure of native parn nuclease domain

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 95
  • Norm. En. per Res.: -5.8949
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-14.9459	-32.5581	-214.729	-262.233	128	13	2	9299	2	85	74
A-D	-133.3067	-60.2195	-366.493	-560.0192	95	20	8	12680	4	30	22
B-C	-130.8448	-45.7031	-78.9842	-255.5321	99	13	8	12691	2	28	22

Interface residues

• A-C: ALA18A, ALA18C, ALA22A, ALA22C, ALA258A, ALA258C, ALA276C, ALA363C, ARG143A, ARG249A, ARG249C, ARG251A, ARG251C, ARG252A, ARG252C, ARG272A, ARG272C, ARG411A, ASN11A, ASN265A, ASN265C, ASN279C, ASP190C, ASP245C, ASP77A, ASP77C, ASP80A, ASP80C, GLN17A, GLN17C, GLN193C, GLN254A, GLN254C, GLN255A, GLN255C, GLN261A, GLU186C, GLU189C, GLU195C, GLU196C, GLU20A, GLU20C, GLU21A, GLU21C, GLU246A, GLU246C, GLU247A, GLU247C, GLU248A, GLU248C, GLU253A, GLU260A, GLU262A, GLU361C, GLU364C, GLY224C, GLY365C, GLY398A, HIS13A, HIS13C, HIS257A, HIS275C, HIS407A, ILE188C, ILE19A, ILE19C, ILE225C, ILE406A, ILE84C, LEU12A, LEU12C, LEU191C, LEU192C, LEU264A, LEU401A, LYS14A, LYS14C, LYS220C, LYS223C, LYS243C, LYS250A, LYS250C, LYS256A, LYS259A, LYS282A, LYS282C, LYS359A, LYS405A, LYS413A, LYS75A, LYS75C, LYS82C, LYS86A, LYS86C, LYS9A, LYS9C, PHE366C, PHE400A, PHE74C, PHE8A, PRO222C, PRO403A, PRO404A, SER10A, SER194C, SER218C, SER280C, SER362C, SER399A, SER402A, SER409A, SER81A, THR73C, THR79A, THR79C, THR85C, TRP219C, TYR16A, TYR16C, TYR221C, TYR76A, TYR76C, TYR78A, TYR78C, VAL15A, VAL15C, VAL185C, VAL408A
• A-D: ALA117A, ALA117D, ARG128A, ARG128D, ARG5A, ARG5D, ARG99D, ASN124A, ASN124D, ASN129A, ASN129D, ASP103A, ASP103D, ASP114A, ASP114D, ASP122A, ASP122D, ASP36A, ASP36D, ASP63A, ASP63D, CYS108A, CYS108D, GLN109A, GLN109D, GLN119A, GLN119D, GLY120A, GLY120D, GLY130A, GLY130D, GLY33A, GLY33D, GLY37D, HIS60A, HIS60D, ILE113A, ILE113D, ILE34A, ILE34D, LEU116A, LEU116D, LEU376A, LEU65A, LEU65D, LYS105A, LYS105D, LYS125A, LYS125D, LYS234D, LYS348A, LYS95A, LYS95D, PHE106A, PHE106D, PHE115A, PHE115D, PHE121A, PHE121D, PHE123A, PHE123D, PHE127A, PHE127D, PHE64A, PHE64D, PHE67A, PHE67D, PHE93A, PHE93D, PRO102A, PRO102D, PRO38D, PRO94A, PRO94D, PRO96A, PRO96D, SER110A, SER110D, SER111A, SER111D, SER112A, SER112D, SER118A, SER118D, SER32A, SER32D, SER35A, SER35D, TYR133A, VAL104A, VAL104D, VAL107A, VAL107D, VAL126A, VAL126D
• B-C: ALA117B, ALA117C, ARG128B, ARG128C, ARG5B, ARG5C, ARG99B, ARG99C, ASN124B, ASN124C, ASN129B, ASN129C, ASN98C, ASP103B, ASP103C, ASP114B, ASP114C, ASP122B, ASP122C, ASP36B, ASP36C, ASP63B, ASP63C, CYS108B, CYS108C, GLN109B, GLN109C, GLN119B, GLN119C, GLY120B, GLY120C, GLY130B, GLY130C, GLY33B, GLY33C, GLY37B, HIS60B, ILE113B, ILE113C, ILE34B, ILE34C, LEU116B, LEU116C, LEU65B, LEU65C, LYS105B, LYS105C, LYS125B, LYS125C, LYS95B, LYS95C, PHE106B, PHE106C, PHE115B, PHE115C, PHE121B, PHE121C, PHE123B, PHE123C, PHE127B, PHE127C, PHE64B, PHE64C, PHE67B, PHE67C, PHE93B, PHE93C, PHE97C, PRO102B, PRO102C, PRO38B, PRO94B, PRO94C, PRO96B, PRO96C, SER101B, SER101C, SER110B, SER110C, SER111B, SER111C, SER112B, SER112C, SER118B, SER118C, SER32B, SER32C, SER35B, SER35C, SER39B, TYR133B, TYR133C, TYR91B, VAL104B, VAL104C, VAL107B, VAL107C, VAL126B, VAL126C