2A07

crystal structure of foxp2 bound specifically to dna.

• Total interactions analyzed: 45
• Total true interactions: 5
• Strongest Interaction:
  • Chains: H-I
  • Int. Res.: 149
  • Norm. En. per Res.: -5.6585
• Hub Node: F(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
F-G	-47.0231	-53.16	-701.94	-802.1231	147	18	23	26530	3	25	32
F-J	0.0	1.2105	-8.2714	-7.061	19	0	0	736	0	4	11
H-I	-58.3468	-65.7809	-718.994	-843.1217	149	13	24	27265	4	25	32
I-K	0.0	1.5834	-11.967	-10.3836	19	1	0	806	0	4	10
J-K	0.0	0.0	-17.6304	-17.6304	18	1	0	1200	0	0	4

Interface residues

• F-G: ALA510F, ALA510G, ALA516F, ALA516G, ALA539F, ALA539G, ALA545F, ALA545G, ALA546G, ALA551F, ALA551G, ALA571F, ALA571G, ARG504F, ARG514F, ARG514G, ARG523F, ARG523G, ARG536F, ARG536G, ARG542F, ARG542G, ARG543F, ARG543G, ARG553F, ARG553G, ARG564F, ARG564G, ARG583F, ARG583G, ARG584F, ARG584G, ASN528F, ASN528G, ASN544F, ASN544G, ASN550F, ASN550G, ASN555F, ASN555G, ASN567F, ASN567G, ASP522F, ASP522G, ASP576F, ASP576G, CYS561F, CYS561G, GLN515F, GLN515G, GLN524F, GLN524G, GLN581G, GLU519F, GLU519G, GLU529F, GLU529G, GLU566F, GLU577F, GLU577G, GLY570F, GLY570G, HIS554F, HIS554G, HIS559F, HIS559G, ILE513F, ILE513G, ILE517F, ILE517G, ILE530F, ILE530G, LEU512F, LEU512G, LEU525F, LEU525G, LEU527F, LEU527G, LEU556F, LEU556G, LEU558F, LEU558G, LYS549F, LYS549G, LYS569F, LYS569G, MET518F, MET518G, PHE507F, PHE507G, PHE534F, PHE534G, PHE538F, PHE538G, PHE541F, PHE541G, PHE562F, PHE562G, PRO505F, PRO506F, PRO506G, SER520F, SER520G, SER532F, SER532G, SER557F, SER557G, THR508F, THR508G, THR511F, THR511G, THR526F, THR526G, THR535F, THR535G, THR537F, THR537G, THR547F, THR547G, THR574F, THR574G, TRP533F, TRP533G, TRP548F, TRP548G, TRP573F, TRP573G, TYR509F, TYR509G, TYR531F, TYR531G, TYR540F, TYR540G, TYR580F, TYR580G, VAL503F, VAL552F, VAL552G, VAL563F, VAL563G, VAL565F, VAL565G, VAL568G, VAL572F, VAL572G, VAL575F, VAL575G
• F-J: ARG564F, ARG583F, ARG583J, GLU579F, GLU579J, HIS554F, HIS554J, HIS559F, HIS559J, LEU556F, LEU558F, LEU558J, LYS560F, LYS560J, LYS582F, LYS582J, SER557F, SER557J, TRP573F
• H-I: ALA510H, ALA510I, ALA516H, ALA516I, ALA539H, ALA539I, ALA545H, ALA545I, ALA546H, ALA551H, ALA551I, ALA571H, ALA571I, ARG504I, ARG514H, ARG514I, ARG523H, ARG523I, ARG536H, ARG536I, ARG542H, ARG542I, ARG543H, ARG543I, ARG553H, ARG553I, ARG564H, ARG564I, ARG583H, ARG583I, ARG584H, ASN528H, ASN528I, ASN544H, ASN544I, ASN550H, ASN550I, ASN555H, ASN555I, ASN567H, ASN567I, ASP522H, ASP522I, ASP576H, ASP576I, CYS561H, CYS561I, GLN515H, GLN515I, GLN524H, GLN524I, GLN581H, GLN581I, GLU519H, GLU519I, GLU529H, GLU529I, GLU566H, GLU566I, GLU577H, GLU577I, GLY570H, GLY570I, HIS554H, HIS554I, HIS559H, HIS559I, ILE513H, ILE513I, ILE517H, ILE517I, ILE530H, ILE530I, LEU512H, LEU512I, LEU525H, LEU525I, LEU527H, LEU527I, LEU556H, LEU556I, LEU558H, LEU558I, LYS549H, LYS549I, LYS569H, LYS569I, MET518H, MET518I, PHE507H, PHE507I, PHE534H, PHE534I, PHE538H, PHE538I, PHE541H, PHE541I, PHE562H, PHE562I, PRO505I, PRO506H, PRO506I, SER520H, SER520I, SER521H, SER532H, SER532I, SER557H, SER557I, THR508H, THR508I, THR511H, THR511I, THR526H, THR526I, THR535H, THR535I, THR537H, THR537I, THR547H, THR547I, THR574H, THR574I, TRP533H, TRP533I, TRP548H, TRP548I, TRP573H, TRP573I, TYR509H, TYR509I, TYR531H, TYR531I, TYR540H, TYR540I, TYR580H, TYR580I, VAL503I, VAL552H, VAL552I, VAL563H, VAL563I, VAL565H, VAL565I, VAL572H, VAL572I, VAL575H, VAL575I, VAL578H
• I-K: ARG564I, ARG583I, ARG583K, GLU579I, GLU579K, HIS554I, HIS554K, HIS559I, HIS559K, LEU556I, LEU558I, LEU558K, LYS560I, LYS560K, LYS582I, LYS582K, SER557I, SER557K, TRP573I
• J-K: ARG504J, ARG504K, ARG543J, ARG543K, ASN544J, ASN544K, ILE502J, ILE502K, PRO505J, PRO505K, PRO506J, PRO506K, THR547J, THR547K, TYR540J, TYR540K, VAL503J, VAL503K