1ZC4

crystal structure of the ral-binding domain of exo84 in complex with the active rala

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 92
  • Norm. En. per Res.: -3.7076
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-76.192	-46.0862	-218.818	-341.0962	92	14	8	9513	7	41	39
B-C	-67.8164	-32.3859	-227.435	-327.6373	95	10	8	9509	5	43	41
B-D	-21.232	0.5863	-158.65	-179.2957	82	10	7	7081	3	14	12

Interface residues

• A-D: ALA13A, ALA185D, ALA189D, ALA228D, ALA48A, ALA70A, ALA76A, ALA77A, ARG226D, ARG273D, ARG279D, ARG280D, ARG52A, ARG79A, ARG84A, ASN231D, ASN235D, ASN81A, ASP186D, ASP225D, ASP234D, ASP277D, ASP49A, ASP65A, ASP68A, ASP74A, ASP80A, GLN63A, GLU184D, GLU249D, GLU266D, GLU269D, GLU270D, GLU73A, GLU87A, GLY86A, HIS187D, ILE18A, ILE252D, ILE64A, ILE66A, ILE78A, LEU12A, LEU14A, LEU224D, LEU227D, LEU244D, LEU245D, LEU265D, LEU268D, LEU275D, LEU32A, LEU67A, LEU72A, LYS16A, LYS233D, LYS243D, LYS261D, LYS272D, LYS278D, LYS47A, LYS53A, LYS54A, MET188D, MET238D, MET241D, MET246D, MET35A, PHE242D, PHE247D, PHE83A, PRO223D, PRO236D, PRO237D, PRO248D, SER11A, SER250D, SER276D, SER50A, SER85A, THR31A, THR46A, THR69A, TYR222D, TYR36A, TYR51A, TYR75A, TYR82A, VAL114A, VAL229D, VAL230D, VAL232D
• B-C: ALA13C, ALA185B, ALA189B, ALA228B, ALA274B, ALA48C, ALA70C, ALA76C, ALA77C, ARG226B, ARG273B, ARG279B, ARG280B, ARG52C, ARG79C, ARG84C, ASN231B, ASN235B, ASN81C, ASP186B, ASP225B, ASP234B, ASP277B, ASP49C, ASP65C, ASP68C, ASP74C, ASP80C, GLN63C, GLU184B, GLU249B, GLU266B, GLU269B, GLU270B, GLU38C, GLU73C, GLU87C, GLY86C, HIS187B, ILE18C, ILE252B, ILE64C, ILE66C, ILE78C, LEU12C, LEU14C, LEU224B, LEU227B, LEU244B, LEU245B, LEU265B, LEU268B, LEU275B, LEU32C, LEU67C, LEU72C, LYS115C, LYS16C, LYS233B, LYS243B, LYS261B, LYS272B, LYS278B, LYS47C, LYS53C, LYS54C, MET188B, MET238B, MET241B, MET246B, MET35C, PHE242B, PHE247B, PHE83C, PRO223B, PRO236B, PRO237B, PRO248B, SER11C, SER250B, SER276B, SER50C, SER85C, THR31C, THR46C, THR69C, TYR222B, TYR36C, TYR51C, TYR75C, TYR82C, VAL114C, VAL229B, VAL230B, VAL232B
• B-D: ALA206B, ALA206D, ALA220B, ALA220D, ARG193B, ARG193D, ARG217B, ARG217D, ARG226B, ARG226D, ARG279B, ARG279D, ASN177B, ASN177D, ASN200B, ASN200D, ASN219B, ASN219D, ASP179B, ASP179D, ASP201B, ASP201D, ASP225B, ASP225D, CYS202B, CYS202D, GLN172B, GLN172D, GLU282B, GLU282D, GLY171B, GLY171D, GLY178B, GLY178D, GLY196B, GLY196D, HIS195B, HIS195D, LEU174B, LEU174D, LEU180D, LEU198B, LEU198D, LEU203B, LEU203D, LEU204B, LEU204D, LEU221B, LEU221D, LEU224B, LEU224D, LEU275B, LEU275D, LYS278B, LYS278D, MET199B, MET199D, MET215B, MET215D, MET246B, PHE197B, PHE197D, PRO223B, PRO223D, THR207B, THR207D, TRP208B, TRP208D, TYR173B, TYR173D, TYR176B, TYR176D, TYR218B, TYR218D, TYR222B, TYR222D, VAL175B, VAL175D, VAL194B, VAL194D, VAL205B, VAL205D