1Z8L

crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 229
  • Norm. En. per Res.: -2.2676
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-55.5825	39.67	-503.368	-519.2804	229	34	14	22955	3	63	73
A-C	0.0	-17.9272	-35.0141	-52.9413	38	4	0	2080	0	22	12
A-D	0.0	0.0	-0.2786	-0.2786	8	0	0	121	0	0	1
B-C	0.0	0.0	-1.8266	-1.8266	9	0	0	374	0	0	1
B-D	0.0	-17.376	-40.8977	-58.2737	40	12	0	2945	0	26	13
C-D	-35.3798	55.8823	-539.518	-519.0155	236	42	14	24069	5	65	72

Interface residues

• A-B: ALA274A, ALA274B, ALA278A, ALA278B, ALA284A, ALA284B, ALA365A, ALA365B, ALA435A, ALA435B, ALA635A, ALA635B, ALA674A, ALA674B, ALA735A, ALA735B, ALA736A, ALA736B, ALA741A, ALA741B, ALA742A, ALA742B, ALA743A, ALA743B, ALA750A, ALA750B, ARG280A, ARG280B, ARG281A, ARG281B, ARG363A, ARG363B, ARG370A, ARG370B, ARG411A, ARG411B, ARG413A, ARG413B, ARG414A, ARG440A, ARG440B, ARG445A, ARG445B, ARG527A, ARG527B, ARG649A, ARG649B, ARG662A, ARG662B, ARG673A, ARG673B, ARG688A, ARG688B, ARG730A, ARG730B, ASN275A, ASN275B, ASN438A, ASN438B, ASN657A, ASN657B, ASP106A, ASP106B, ASP369A, ASP369B, ASP630A, ASP630B, ASP666A, ASP666B, ASP677A, ASP677B, GLN443A, GLN443B, GLN667A, GLN667B, GLN731A, GLN731B, GLN740A, GLN740B, GLU276A, GLU276B, GLU285A, GLU285B, GLU367A, GLU367B, GLU433A, GLU433B, GLU436A, GLU436B, GLU437A, GLU437B, GLU444A, GLU444B, GLU672A, GLU672B, GLU727A, GLU727B, GLU744A, GLU744B, GLU748A, GLU748B, GLY271A, GLY271B, GLY364A, GLY364B, GLY680A, GLY680B, GLY726A, GLY726B, HIS689B, ILE416A, ILE416B, ILE659A, ILE659B, ILE676A, ILE676B, ILE732A, ILE732B, LEU268A, LEU268B, LEU362A, LEU362B, LEU417A, LEU417B, LEU441A, LEU441B, LEU528A, LEU528B, LEU632A, LEU632B, LEU661A, LEU661B, LEU671A, LEU671B, LEU679A, LEU679B, LEU681A, LEU681B, LEU746A, LEU746B, LYS723A, LYS723B, LYS729A, LYS729B, MET663A, MET663B, MET664A, MET664B, MET669A, MET669B, PHE646A, PHE646B, PHE670A, PHE670B, PHE675A, PHE675B, PHE686A, PHE686B, PHE737A, PHE737B, PRO270A, PRO270B, PRO273A, PRO273B, PRO368A, PRO368B, PRO658A, PRO658B, PRO678A, PRO678B, PRO682A, PRO682B, PRO685A, PRO685B, SER107A, SER107B, SER439A, SER439B, SER628A, SER628B, SER631A, SER631B, SER634A, SER634B, SER656A, SER722A, SER722B, SER747A, SER747B, THR269A, THR269B, THR361A, THR361B, THR415A, THR415B, THR738A, THR738B, THR745A, THR745B, TRP434A, TRP725A, TRP725B, TYR113A, TYR113B, TYR272A, TYR272B, TYR277A, TYR277B, TYR279A, TYR279B, TYR371A, TYR371B, TYR625B, TYR733A, TYR733B, VAL366A, VAL366B, VAL660A, VAL660B, VAL690A, VAL690B, VAL728A, VAL728B, VAL734A, VAL734B, VAL739A, VAL739B, VAL749A, VAL749B
• A-C: 0158CB9.9643, ARG413A, ARG413C, ARG662A, ASN57A, ASN57C, ASN589A, ASN589C, ASN657A, ASN657C, ASN665A, ASN665C, ASP652A, ASP652C, ASP654A, ASP654C, GLU648C, HIS56A, HIS56A5, HIS56C, ILE591A, ILE591C, ILE659A, ILE659C, LEU661A, LEU661C, LYS655A, LYS655C, PHE653A, PHE653C, PRO658A, PRO658C, SER656A, SER656C, VAL366A, VAL366C, VAL592A, VAL592C
• A-D: ASN657A, ASN657D, ILE659A, ILE659D, PRO658A, PRO658D, SER656A, SER656D
• B-C: ASN657B, ASN657C, ASP654B, ILE659B, ILE659C, PRO658B, PRO658C, SER656B, SER656C
• B-D: ARG413B, ARG413D, ARG662B, ARG662D, ASN57B, ASN57D, ASN589B, ASN589D, ASN657B, ASN657D, ASN665B, ASN665D, ASP652B, ASP652D, ASP654B, ASP654D, GLU367D, GLU648B, HIS56B, HIS56D, ILE591B, ILE591D, ILE659B, ILE659D, LEU661B, LEU661D, LYS655B, LYS655D, PHE653B, PHE653D, PRO658B, PRO658D, SER590B, SER590D, SER656B, SER656D, VAL366B, VAL366D, VAL592B, VAL592D
• C-D: ALA274C, ALA274D, ALA278C, ALA278D, ALA284C, ALA284D, ALA365C, ALA365D, ALA435C, ALA435D, ALA635C, ALA635D, ALA674C, ALA674D, ALA724D, ALA735C, ALA735D, ALA736C, ALA736D, ALA741C, ALA741D, ALA742C, ALA742D, ALA743C, ALA743D, ALA750C, ALA750D, ARG280C, ARG280D, ARG281C, ARG281D, ARG363C, ARG363D, ARG370C, ARG370D, ARG411C, ARG411D, ARG413C, ARG413D, ARG414C, ARG414D, ARG440C, ARG440D, ARG445C, ARG445D, ARG527C, ARG527D, ARG649C, ARG649D, ARG662C, ARG662D, ARG673C, ARG673D, ARG688C, ARG688D, ARG730C, ARG730D, ASN275C, ASN275D, ASN438C, ASN438D, ASN657C, ASN657D, ASP106C, ASP106D, ASP369C, ASP369D, ASP630C, ASP630D, ASP666C, ASP666D, ASP677C, ASP677D, GLN443C, GLN443D, GLN667C, GLN667D, GLN731C, GLN731D, GLN740C, GLN740D, GLU276C, GLU276D, GLU285C, GLU285D, GLU367C, GLU367D, GLU433C, GLU433D, GLU436C, GLU436D, GLU437C, GLU437D, GLU444C, GLU444D, GLU672C, GLU672D, GLU727C, GLU727D, GLU744C, GLU744D, GLU748C, GLU748D, GLY271C, GLY271D, GLY364C, GLY364D, GLY680C, GLY680D, GLY726C, GLY726D, HIS689C, HIS689D, ILE416C, ILE416D, ILE659C, ILE659D, ILE676C, ILE676D, ILE732C, ILE732D, LEU268C, LEU268D, LEU362C, LEU362D, LEU417C, LEU417D, LEU441C, LEU441D, LEU528C, LEU528D, LEU632C, LEU632D, LEU661C, LEU661D, LEU671C, LEU671D, LEU679C, LEU679D, LEU681C, LEU681D, LEU746C, LEU746D, LYS723C, LYS723D, LYS729C, LYS729D, MET663C, MET663D, MET664C, MET664D, MET669C, MET669D, PHE646C, PHE646D, PHE670C, PHE670D, PHE675C, PHE675D, PHE686C, PHE686D, PHE737C, PHE737D, PRO270C, PRO270D, PRO273C, PRO273D, PRO368C, PRO368D, PRO658C, PRO658D, PRO678C, PRO678D, PRO682C, PRO682D, PRO685C, PRO685D, SER107C, SER107D, SER439C, SER439D, SER628C, SER628D, SER631C, SER631D, SER634C, SER634D, SER656C, SER656D, SER722C, SER722D, SER747C, SER747D, THR269C, THR269D, THR361C, THR361D, THR415C, THR415D, THR738C, THR738D, THR745C, THR745D, TRP434C, TRP434D, TRP725C, TRP725D, TYR113C, TYR113D, TYR272C, TYR272D, TYR277C, TYR277D, TYR279C, TYR279D, TYR371C, TYR371D, TYR625C, TYR625D, TYR733C, TYR733D, VAL366C, VAL366D, VAL627D, VAL660C, VAL660D, VAL690C, VAL690D, VAL728C, VAL728D, VAL734C, VAL734D, VAL739C, VAL739D, VAL749C, VAL749D