1YUC

human nuclear receptor liver receptor homologue-1, lrh-1, bound to phospholipid and a fragment of human shp

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 83
  • Norm. En. per Res.: -4.2641
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-68.2523	-74.4421	-211.23	-353.9244	83	15	1	7585	9	23	26
A-C	-11.2028	-10.4131	-162.651	-184.2669	50	3	6	6610	0	3	3
B-D	-35.7629	-6.8555	-143.769	-186.3874	46	13	6	5994	0	4	4

Interface residues

• A-B: ALA420A, ALA420B, ARG333A, ARG333B, ASN332B, ASN523A, ASN523B, ASN529A, ASN529B, ASN530A, ASN530B, ASP525A, ASP525B, GLN419A, GLN419B, GLU329A, GLU329B, GLU337A, GLU337B, GLY343A, GLY343B, GLY421A, GLY421B, GLY524A, GLY524B, HIS336A, HIS336B, HIS521A, HIS521B, HIS537A, HIS537B, ILE415A, ILE415B, ILE416A, ILE416B, ILE533A, ILE533B, LEU339A, LEU339B, LEU344A, LEU344B, LEU424A, LEU424B, LEU517A, LEU517B, LEU522A, LEU522B, LEU532B, LEU536A, LEU536B, LYS335A, LYS335B, LYS338A, LYS338B, LYS347A, LYS347B, LYS520A, LYS520B, MET345A, MET345B, PHE342A, PHE342B, PRO527A, PRO527B, SER334A, SER334B, SER340A, SER340B, SER418A, SER418B, THR341A, THR341B, TYR516A, TYR516B, TYR518A, TYR518B, TYR519B, TYR528A, TYR528B, VAL411A, VAL411B, VAL526A, VAL526B
• A-C: ALA19C, ALA23C, ALA360A, ALA538A, ARG17C, ARG361A, ARG367A, ASN380A, ASN529A, ASN530A, ASP350A, ASP372A, ASP373A, GLN374A, GLN379A, GLU358A, GLU534A, HIS537A, ILE20C, ILE356A, ILE533A, LEU21C, LEU24C, LEU25C, LEU353A, LEU369A, LEU377A, LEU378A, LEU456A, LEU531A, LEU532A, LEU536A, LYS370A, LYS376A, MET375A, MET535A, PHE354A, PHE366A, PRO18C, SER16C, SER26C, SER27C, SER28C, SER355A, SER362A, TRP382A, TYR22C, TYR528A, VAL357A, VAL371A
• B-D: ALA19D, ALA23D, ALA360B, ALA538B, ARG17D, ARG361B, ARG367B, ASN380B, ASN529B, ASN530B, ASP350B, ASP372B, ASP373B, GLN374B, GLN379B, GLU358B, GLU534B, HIS537B, ILE20D, ILE356B, ILE533B, LEU21D, LEU24D, LEU25D, LEU353B, LEU369B, LEU377B, LEU378B, LEU531B, LEU532B, LYS370B, LYS376B, LYS539B, MET375B, MET535B, PHE354B, PHE366B, PRO18D, SER26D, SER27D, SER355B, TRP382B, TYR22D, TYR528B, VAL357B, VAL371B