1YMH

anti-hcv fab 19d9d6 complexed with protein l (ppl) mutant a66w

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: A-E
  • Int. Res.: 76
  • Norm. En. per Res.: -3.182
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-30.285	-13.1632	-454.771	-498.2192	194	35	12	20300	0	14	18
A-E	-51.9194	-6.8708	-183.045	-241.8352	76	11	1	7510	0	14	17
A-D	-9.1322	0.0	-44.6318	-53.764	32	5	0	1826	0	3	3
B-E	0.0	1.2923	-5.1902	-3.8979	8	0	0	383	0	2	2
B-C	-8.8282	0.0	-52.0799	-60.9081	34	6	0	2079	0	3	3
B-D	-10.7394	-74.227	-85.0412	-170.0076	76	4	3	4316	7	10	7
C-D	-22.7069	5.8086	-449.222	-466.1204	193	26	11	19090	1	13	18
C-F	-28.0203	4.6337	-142.574	-165.9606	73	10	1	6566	0	17	16
D-F	0.0	1.3434	-1.7458	-0.4024	5	0	0	199	0	2	2

Interface residues

• A-B: ALA100A, ALA105B, ALA125B, ALA129B, ALA130A, ALA130B, ALA168B, ALA34A, ALA51A, ALA60B, ALA91A, ALA93B, ARG211A, ARG213B, ARG94B, ARG98B, ASN133B, ASN137A, ASN138A, ASN157A, ASN161A, ASN210A, ASN212A, ASN27A, ASN31A, ASN38B, ASN46B, ASP101B, ASP165A, ASP167A, ASP170A, ASP1A, ASP1A5, ASP61B, ASP62B, CB9.0118739.80024, CYS134A, CYS140B, CYS214A, CYS88A, CYS92B, GLN124A, GLN131B, GLN171B, GLN37A, GLN38A, GLN39B, GLN42A, GLN6B, GLN90A, GLN99B, GLU123A, GLU213A, GLU55A, GLY101A, GLY104B, GLY106B, GLY127B, GLY128A, GLY129A, GLY139B, GLY144B, GLY158A, GLY162B, GLY41A, GLY42B, GLY44B, GLY49B, GLY99A, HIS164B, HIS35B, ILE117A, ILE210B, ILE48A, ILE93A, LEU124B, LEU125A, LEU136A, LEU138B, LEU141B, LEU160A, LEU170B, LEU174B, LEU177B, LEU179A, LEU181A, LEU33A, LEU45B, LEU47A, LEU96A, LEU96B, LEU97B, LYS143B, LYS169A, LYS207A, LYS208B, LYS209B, LYS30A, LYS43B, LYS45A, LYS89A, MET135B, MET175A, MET48B, PHE100B, PHE118A, PHE135A, PHE139A, PHE166B, PHE209A, PHE91B, PHE95B, PHE98A, PRO119A, PRO120A, PRO123B, PRO126B, PRO167B, PRO212B, PRO40A, PRO44A, PRO94A, PRO95A, SER116A, SER120B, SER121A, SER122A, SER127A, SER128B, SER131A, SER161B, SER162A, SER168A, SER172B, SER174A, SER176A, SER177A, SER178B, SER179B, SER180B, SER208A, SER43A, SER56A, THR114A, THR126A, THR137B, THR164A, THR165B, THR172A, THR176B, THR178A, THR180A, THR182B, THR28A, THR53A, THR58B, THR89B, THR97A, TRP103B, TRP154B, TRP163A, TRP188B, TRP35A, TRP36B, TRP47B, TRP50A, TRP50B, TYR100B, TYR122B, TYR173A, TYR175B, TYR186A, TYR32A, TYR36A, TYR49A, TYR59B, TYR86A, TYR87A, TYR92A, VAL102B, VAL115A, VAL121B, VAL132A, VAL133A, VAL136B, VAL142B, VAL159A, VAL163B, VAL169B, VAL181B, VAL211B, VAL37B, VAL46A, VAL85A
• A-E: ALA100A, ALA12A, ALA15A, ALA837E, ALA846E, ALA848E, ALA850E, ALA854E, ARG65A, ARG852E, ASN826E, ASN861E, ASP70A, ASP831E, CYS23A, GLN6A, GLN835E, GLU105A, GLU17A, GLU819E, GLU838E, GLU845E, GLU849E, GLY101A, GLY16A, GLY66A, GLY832E, GLY841E, GLY99A, ILE75A, ILE823E, ILE834E, LEU104A, LEU11A, LEU73A, LEU827E, LEU856E, LEU857E, LYS103A, LYS107A, LYS142A, LYS18A, LYS24A, LYS818E, LYS824E, LYS833E, LYS840E, LYS859E, MET21A, MET4A, PHE71A, PHE829E, PHE839E, PHE98A, PRO8A, SER10A, SER14A, SER22A, SER5A, SER7A, SER9A, THR102A, THR20A, THR72A, THR74A, THR822E, THR836E, TYR853E, TYR87A, VAL13A, VAL19A, VAL78A, VAL821E, VAL825E, VAL85A, VAL860E
• A-D: ALA24D, ALA75D, ARG54A, ASP31D, ASP60A, GLN1D, GLN3D, GLN42A, GLU55A, GLY26D, GLY57A, ILE2D, LEU4D, LYS23D, LYS45A, PHE29D, PRO44A, SER25D, SER43A, SER56A, SER74D, SER76D, THR28D, THR30D, THR53A, THR73D, THR77D, TRP50A, TYR27D, TYR49A, VAL46A, VAL58A
• B-E: ASN46B, GLN39B, GLU819E, GLY42B, GLY44B, LEU45B, LYS43B, LYS818E
• B-C: ALA24B, ALA75B, ARG54C, ASP31B, ASP60C, GLN1B, GLN3B, GLN42C, GLU55C, GLY26B, GLY57C, ILE2B, LEU4B, LYS23B, LYS45C, PHE29B, PRO44C, PRO59C, SER25B, SER43C, SER56C, SER74B, SER76B, THR28B, THR30B, THR53C, THR73B, THR77B, TRP50C, TYR27B, TYR49C, VAL46C, VAL58C, VAL5B
• B-D: ALA105D, ARG94B, ARG94D, ARG98B, ARG98D, ASN155B, ASN155D, ASN196D, ASP101B, ASP101D, ASP207D, ASP31B, ASP31D, GLN1B, GLN1D, GLN3B, GLN3D, GLU191B, GLU191D, GLU53D, GLY104D, GLY157B, GLY157D, GLY26B, GLY26D, ILE210B, ILE2B, ILE2D, LEU159B, LEU159D, LEU4D, LEU96B, LEU96D, LEU97B, LEU97D, LYS209B, LYS209D, PHE29B, PHE29D, PHE32B, PHE32D, PRO189B, SER156B, SER156D, SER158B, SER158D, SER160D, SER186D, SER190B, SER190D, SER25B, SER25D, THR153D, THR187B, THR187D, THR192B, THR192D, THR194B, THR194D, THR28B, THR28D, THR30B, THR30D, TRP103B, TRP103D, TRP154B, TRP154D, TYR100B, TYR100D, TYR27B, TYR27D, VAL102B, VAL102D, VAL193B, VAL193D, VAL211B
• C-D: ALA100C, ALA105D, ALA125D, ALA129D, ALA130C, ALA130D, ALA168D, ALA34C, ALA51C, ALA60D, ALA91C, ALA93D, ARG211C, ARG213D, ARG27C, ARG94D, ARG98D, ASN133D, ASN137C, ASN138C, ASN161C, ASN210C, ASN27C, ASN31C, ASN38D, ASN46D, ASP101D, ASP165C, ASP167C, ASP170C, ASP1C, ASP61D, ASP62D, CYS134C, CYS140D, CYS214C, CYS88C, CYS92D, GLN124C, GLN131D, GLN171D, GLN37C, GLN38C, GLN39D, GLN42C, GLN6D, GLN90C, GLN99D, GLU123C, GLU213C, GLU55C, GLY101C, GLY104D, GLY106D, GLY127D, GLY129C, GLY139D, GLY158C, GLY162D, GLY41C, GLY42D, GLY44D, GLY49D, GLY99C, HIS164D, HIS35D, ILE117C, ILE205C, ILE210D, ILE48C, ILE93C, LEU124D, LEU125C, LEU136C, LEU138D, LEU141D, LEU160C, LEU170D, LEU174D, LEU177D, LEU179C, LEU33C, LEU45D, LEU47C, LEU96C, LEU96D, LEU97D, LYS143D, LYS169C, LYS207C, LYS208D, LYS30C, LYS43D, LYS45C, LYS64D, LYS89C, MET135D, MET175C, MET48D, PHE100D, PHE118C, PHE135C, PHE139C, PHE166D, PHE209C, PHE63D, PHE91D, PHE95D, PHE98C, PRO113C, PRO119C, PRO120C, PRO123D, PRO126D, PRO167D, PRO44C, PRO94C, PRO95C, SER116C, SER120D, SER121C, SER122C, SER127C, SER128D, SER131C, SER134D, SER160D, SER161D, SER162C, SER168C, SER172D, SER174C, SER176C, SER177C, SER178D, SER179D, SER180D, SER208C, SER43C, SER56C, THR114C, THR126C, THR132D, THR137D, THR164C, THR165D, THR172C, THR176D, THR178C, THR180C, THR182D, THR28C, THR53C, THR58D, THR89D, THR97C, TRP103D, TRP154D, TRP163C, TRP188D, TRP35C, TRP36D, TRP47D, TRP50C, TRP50D, TYR100D, TYR122D, TYR173C, TYR175D, TYR186C, TYR32C, TYR36C, TYR49C, TYR59D, TYR86C, TYR87C, TYR92C, VAL102D, VAL115C, VAL121D, VAL132C, VAL133C, VAL136D, VAL142D, VAL159C, VAL163D, VAL169D, VAL181D, VAL206C, VAL211D, VAL37D, VAL46C, VAL85C
• C-F: ALA100C, ALA12C, ALA15C, ALA837F, ALA850F, ALA854F, ARG65C, ARG852F, ASN826F, ASN861F, ASP143C, ASP70C, ASP831F, CYS23C, GLN6C, GLN835F, GLU105C, GLU17C, GLU819F, GLU838F, GLU845F, GLU849F, GLY16C, GLY66C, GLY832F, GLY841F, ILE75C, ILE823F, ILE828F, ILE834F, LEU104C, LEU11C, LEU73C, LEU827F, LEU856F, LEU857F, LYS103C, LYS107C, LYS142C, LYS18C, LYS24C, LYS818F, LYS824F, LYS833F, LYS840F, LYS859F, LYS882F, MET21C, PHE71C, PHE829F, PHE839F, PRO141C, PRO8C, SER10C, SER14C, SER22C, SER5C, SER7C, SER9C, THR102C, THR20C, THR72C, THR74C, THR822F, THR836F, TYR140C, TYR853F, VAL13C, VAL19C, VAL78C, VAL821F, VAL825F, VAL860F
• D-F: ALA40D, ASN46D, GLU819F, LYS43D, LYS818F