1YM7

g protein-coupled receptor kinase 2 (grk2)

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 72
  • Norm. En. per Res.: -2.0045
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-7.0526	92.2499	-87.4117	-2.2144	82	8	0	4854	10	45	39
A-C	-9.0061	39.5983	-154.509	-123.9168	70	12	6	7846	2	25	27
B-D	-3.5656	31.4687	-172.229	-144.3259	72	4	6	8028	3	26	31

Interface residues

• A-B: ALA650A, ARG507A, ARG507B, ARG50A, ARG648A, ARG648B, ARG652A, ARG652B, ASN508A, ASN508B, ASN570A, ASN570B, ASP500A, ASP500B, ASP502A, ASP502B, ASP649A, ASP649B, GLN503A, GLN607B, GLN613A, GLN613B, GLN629A, GLN629B, GLU504A, GLU504B, GLU610A, GLU610B, GLU611A, GLU611B, GLU646A, GLU646B, GLY626A, GLY626B, GLY627A, GLY627B, ILE241A, ILE614A, ILE614B, LEU237A, LEU499A, LEU499B, LEU505A, LEU505B, LEU621A, LEU621B, LEU622A, LEU622B, LEU647A, LEU647B, LYS615A, LYS615B, LYS618A, LYS618B, LYS623A, LYS623B, LYS628A, LYS628B, LYS644A, LYS644B, LYS645A, LYS645B, MET568A, MET568B, PHE630A, PHE630B, SER501A, SER501B, SER608A, SER608B, THR574A, THR574B, THR612A, THR612B, TYR651A, TYR651B, VAL609A, VAL609B, VAL631A, VAL631B, VAL641A, VAL641B
• A-C: ALA119A, ALA119C, ALA128A, ARG106A, ARG106C, ASP110A, ASP110C, CYS120A, CYS120C, GLN133A, GLN133C, GLN140A, GLN140C, GLU107A, GLU107C, GLU116A, GLU116C, GLU130A, GLU130C, GLY134A, GLY134C, HIS122A, HIS122C, HIS135A, HIS135C, ILE108C, ILE113A, ILE113C, ILE129A, ILE129C, LEU102A, LEU102C, LEU117A, LEU117C, LEU118A, LEU118C, LEU136A, LEU136C, LYS115A, LYS115C, LYS126A, LYS126C, LYS138A, LYS138C, LYS139A, LYS139C, MET114A, MET114C, PHE109A, PHE109C, PHE124A, PHE124C, PRO123A, SER105A, SER105C, SER121A, SER121C, SER125A, SER125C, SER127A, THR111A, THR111C, TYR112C, TYR149A, VAL103A, VAL103C, VAL132C, VAL137A, VAL137C, VAL141C
• B-D: ALA119B, ALA119D, ARG106B, ARG106D, ASP110B, ASP110D, CYS120B, CYS120D, GLN133B, GLN133D, GLN140B, GLN140D, GLU107B, GLU107D, GLU116B, GLU116D, GLU130B, GLU130D, GLY134B, GLY134D, HIS122B, HIS122D, HIS135B, HIS135D, ILE108B, ILE108D, ILE113B, ILE113D, ILE129B, ILE129D, LEU102B, LEU102D, LEU117B, LEU117D, LEU118B, LEU118D, LEU136B, LEU136D, LYS115B, LYS115D, LYS126B, LYS126D, LYS138B, LYS138D, LYS139B, LYS139D, MET114B, MET114D, PHE109B, PHE109D, PHE124B, PHE124D, SER105B, SER105D, SER121B, SER121D, SER125B, SER125D, SER127B, SER127D, THR111B, THR111D, TYR112B, TYR149D, VAL103B, VAL103D, VAL132B, VAL132D, VAL137B, VAL137D, VAL141B, VAL141D