1YK1

structure of natriuretic peptide receptor-c complexed with brain natriuretic peptide

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-E
  • Int. Res.: 67
  • Norm. En. per Res.: -2.9734
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-20.6229	-9.3612	-130.544	-160.5281	73	6	6	6159	3	28	21
A-E	-17.7828	-28.328	-153.105	-199.2158	67	15	3	7200	1	20	16
B-E	-15.4496	-17.6528	-175.073	-208.1754	73	6	4	7365	1	27	18

Interface residues

• A-B: ALA102A, ALA102B, ALA76A, ALA76B, ALA77A, ALA77B, ALA78A, ALA78B, ALA81A, ALA81B, ALA94A, ALA96A, ALA96B, ALA99A, ALA99B, ARG100A, ARG100B, ARG166A, ARG166B, ARG66A, ARG66B, ARG74A, ARG74B, ARG79A, ARG79B, ASN65A, ASN65B, ASP73A, ASP73B, GLU125A, GLU125B, GLU177B, GLY64A, GLY64B, GLY80A, GLY80B, HIS104A, HIS104B, HIS176B, LEU101A, LEU101B, LEU68A, LEU68B, LEU71A, LEU71B, LYS163A, LYS163B, LYS82A, LYS82B, PHE69A, PHE69B, PRO97A, PRO97B, SER103A, SER103B, SER124A, SER124B, SER70A, SER70B, TRP105A, TRP105B, TYR126A, TYR126B, TYR169A, TYR169B, TYR93A, TYR93B, VAL72A, VAL72B, VAL75A, VAL75B, VAL98A, VAL98B
• A-E: ALA114A, ALA116A, ALA117A, ALA94A, ALA95A, ALA96A, ALA99A, ARG100A, ARG10E, ARG131A, ARG14E, ARG166A, ASN65A, ASP13E, ASP161A, ASP162A, CYS168A, CYS23E, CYS7E, CYS91A, GLN120A, GLN180A, GLU125A, GLU173A, GLU177A, GLU181A, GLU92A, GLY118A, GLY174A, GLY20E, GLY22E, GLY6E, GLY9E, HIS121A, HIS176A, ILE15E, ILE188A, LEU115A, LEU157A, LEU164A, LEU172A, LEU21E, LEU26E, LYS11E, LYS163A, LYS24E, MET12E, PHE119A, PHE170A, PHE8E, PRO97A, SER16E, SER17E, SER187A, SER18E, SER190A, SER19E, THR171A, THR186A, TYR126A, TYR136A, TYR159A, TYR169A, TYR189A, TYR93A, VAL175A, VAL25E
• B-E: ALA116B, ALA117B, ALA137B, ALA67B, ALA94B, ALA96B, ARG100B, ARG10E, ARG14E, ARG166B, ARG66B, ASN205B, ASN65B, ASP13E, ASP161B, ASP162B, ASP192B, ASP196B, ASP198B, ASP201B, ASP62B, CYS23E, CYS63B, CYS7E, CYS91B, GLN120B, GLN180B, GLU125B, GLU165B, GLU173B, GLU177B, GLU193B, GLU92B, GLY118B, GLY174B, GLY20E, GLY22E, GLY64B, GLY6E, GLY9E, HIS121B, HIS176B, ILE15E, ILE188B, ILE202B, LEU164B, LEU197B, LEU21E, LEU26E, LEU68B, LYS11E, LYS163B, LYS195B, LYS24E, MET12E, PHE119B, PHE170B, PHE191B, PHE8E, PRO97B, SER16E, SER17E, SER187B, SER18E, SER190B, SER19E, THR194B, TYR126B, TYR159B, TYR169B, TYR189B, TYR93B, VAL25E