1Y5M

the crystal structure of murine 11b-hydroxysteroid dehydrogenase: an important therapeutic target for diabetes

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 218
  • Norm. En. per Res.: -4.2703
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-113.4613	-61.9652	-755.495	-930.9215	218	40	33	30635	4	34	30

Interface residues

• A-B: ALA153A, ALA153B, ALA172A, ALA172B, ALA181A, ALA181B, ALA185A, ALA185B, ALA189A, ALA189B, ALA233A, ALA233B, ALA99A, ALA99B, ARG137A, ARG137B, ARG138A, ARG138B, ARG198A, ARG198B, ARG273A, ARG273B, ARG282A, ARG282B, ASN232A, ASN232B, ASN270A, ASN270B, ASN285A, ASN285B, ASP131A, ASP131B, ASP132A, ASP132B, ASP191A, ASP191B, ASP259A, ASP259B, ASP287A, ASP287B, ASP95A, ASP95B, GLN177A, GLN177B, GLN234A, GLN234B, GLU100A, GLU100B, GLU141A, GLU141B, GLU200A, GLU200B, GLU226B, GLU277A, GLU277B, GLU94A, GLU94B, GLY173A, GLY173B, GLY192A, GLY192B, GLY229A, GLY229B, GLY269A, GLY269B, GLY272A, GLY272B, HIS130A, HIS130B, HIS134A, HIS134B, ILE133A, ILE133B, ILE180A, ILE180B, ILE197A, ILE197B, ILE203A, ILE203B, ILE227A, ILE227B, ILE230A, ILE230B, ILE231A, ILE231B, ILE266A, ILE266B, ILE275A, ILE275B, LEU126A, LEU126B, LEU128A, LEU128B, LEU145A, LEU145B, LEU155A, LEU155B, LEU171A, LEU171B, LEU190A, LEU190B, LEU201A, LEU201B, LEU212A, LEU212B, LEU217A, LEU217B, LEU263A, LEU263B, LEU267A, LEU267B, LEU268A, LEU268B, LEU281A, LEU281B, LYS159A, LYS159B, LYS174A, LYS174B, LYS187A, LYS187B, LYS260A, LYS260B, LYS274A, LYS274B, LYS286A, LYS286B, MET140A, MET140B, MET150A, MET150B, MET175A, MET175B, MET179A, MET179B, MET276A, MET276B, MET288A, MET288B, MET96A, MET96B, PHE129A, PHE129B, PHE144A, PHE144B, PHE188A, PHE188B, PHE193A, PHE193B, PHE194A, PHE194B, PHE278A, PHE278B, PHE279A, PHE279B, PHE289A, PHE289B, PRO156A, PRO156B, PRO178A, PRO178B, PRO182A, PRO182B, PRO265A, PRO265B, PRO271A, PRO271B, SER127A, SER127B, SER135A, SER135B, SER146A, SER146B, SER151A, SER151B, SER184A, SER184B, SER186A, SER186B, SER195A, SER195B, SER228A, SER228B, SER261A, SER261B, SER280A, SER280B, THR152A, THR152B, THR176A, THR176B, THR196A, THR196B, THR199A, THR199B, THR204A, THR204B, THR264A, THR264B, THR97A, THR97B, TYR183A, TYR183B, TYR202B, TYR283A, TYR283B, TYR284A, TYR284B, VAL136A, VAL136B, VAL139A, VAL139B, VAL148A, VAL148B, VAL149A, VAL149B, VAL206A, VAL206B