1Y2M

crystal structure of phenylalanine ammonia-lyase from yeast rhododporidium toruloides

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 339
  • Norm. En. per Res.: -4.8986
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-176.5613	-80.8008	-1082.26	-1339.6221	319	37	13	41316	7	75	95
A-C	-281.6083	-231.0388	-1147.97	-1660.6172	339	50	32	45204	30	110	124
A-D	-48.635	44.2895	-371.825	-376.1706	159	8	12	14589	1	27	44
B-C	-34.7005	41.4722	-370.055	-363.2833	161	7	12	14369	2	26	43
B-D	-279.2175	-221.7391	-1146.13	-1647.0866	340	51	32	45280	29	110	126
C-D	-204.3093	-117.2625	-1060.4	-1381.9718	313	28	12	39902	10	72	95

Interface residues

• A-B: ALA211A, ALA211B, ALA26A, ALA26B, ALA276A, ALA276B, ALA33B, ALA382A, ALA382B, ALA384A, ALA384B, ALA390A, ALA390B, ALA415A, ALA415B, ALA416A, ALA416B, ALA417A, ALA417B, ALA419A, ALA419B, ALA430A, ALA430B, ALA485A, ALA485B, ALA495A, ALA495B, ALA498A, ALA498B, ALA501A, ALA501B, ALA506A, ALA506B, ARG178A, ARG178B, ARG320A, ARG320B, ARG359A, ARG359B, ARG362A, ARG362B, ARG366A, ARG366B, ARG426A, ARG426B, ASN270A, ASN270B, ASN397A, ASN397B, ASN404A, ASN404B, ASN412A, ASN412B, ASN420A, ASN420B, ASN436A, ASN436B, ASN445A, ASN445B, ASN486A, ASN486B, ASN499A, ASN499B, ASN503A, ASN503B, ASP317A, ASP317B, ASP361A, ASP361B, ASP378A, ASP378B, ASP396A, ASP396B, ASP401A, ASP401B, GLN325A, GLN325B, GLN360A, GLN360B, GLN370A, GLN370B, GLN392A, GLN392B, GLN414A, GLN414B, GLN41B, GLN431A, GLN431B, GLN439A, GLN439B, GLN493A, GLN493B, GLN500A, GLN500B, GLU346A, GLU346B, GLU348A, GLU348B, GLU389A, GLU389B, GLU403A, GLU403B, GLU423A, GLU423B, GLU442A, GLU442B, GLU496A, GLU496B, GLY179A, GLY179B, GLY213A, GLY213B, GLY271A, GLY271B, GLY309A, GLY309B, GLY34B, GLY373A, GLY373B, GLY391A, GLY391B, GLY410A, GLY410B, GLY411A, GLY411B, GLY428A, GLY428B, GLY433A, GLY433B, GLY482A, GLY482B, HIS180A, HIS180B, HIS307A, HIS307B, HIS312A, HIS312B, HIS316A, HIS316B, HIS322A, HIS322B, HIS345A, HIS345B, HIS36A, HIS381A, HIS381B, HIS383B, HIS408A, HIS408B, HIS409A, HIS409B, HIS483A, HIS483B, HIS491A, HIS491B, ILE209A, ILE209B, ILE326A, ILE326B, ILE380A, ILE380B, ILE388A, ILE388B, ILE400A, ILE400B, ILE432A, ILE432B, ILE47B, LEU215A, LEU215B, LEU266A, LEU266B, LEU30A, LEU30B, LEU315A, LEU315B, LEU358A, LEU358B, LEU365A, LEU365B, LEU372A, LEU372B, LEU375A, LEU375B, LEU379A, LEU379B, LEU37A, LEU386A, LEU386B, LEU399A, LEU399B, LEU427A, LEU427B, LEU429A, LEU429B, LEU435A, LEU435B, LEU481A, LEU481B, LEU484A, LEU484B, LEU505A, LEU505B, LYS350B, LYS405A, LYS405B, LYS424A, LYS424B, LYS434A, LYS434B, PHE311A, PHE311B, PHE314A, PHE314B, PHE413A, PHE413B, PHE437A, PHE437B, PRO313A, PRO313B, PRO321A, PRO321B, PRO323A, PRO323B, PRO364A, PRO364B, PRO369A, PRO369B, PRO374A, PRO374B, PRO38A, PRO398A, PRO398B, PRO487A, PRO487B, PRO494A, PRO494B, SER175A, SER175B, SER181A, SER181B, SER210A, SER210B, SER212A, SER212B, SER310A, SER310B, SER35A, SER368A, SER368B, SER377A, SER377B, SER393A, SER393B, SER407A, SER407B, SER479A, SER479B, SER504A, SER504B, SER509A, SER509B, THR272A, THR272B, THR319A, THR319B, THR324A, THR324B, THR367A, THR367B, THR387A, THR387B, THR394A, THR394B, THR395A, THR395B, THR39A, THR39B, THR406A, THR406B, THR40A, THR40B, THR421A, THR421B, THR438A, THR438B, THR441A, THR441B, THR478A, THR478B, THR489A, THR489B, THR490A, THR490B, TRP371A, TRP371B, TYR363A, TYR363B, TYR65A, TYR65B, VAL318A, VAL318B, VAL349A, VAL349B, VAL376A, VAL376B, VAL385A, VAL385B, VAL402A, VAL402B, VAL418A, VAL418B, VAL42B, VAL488A, VAL488B, VAL492A, VAL492B, VAL502A, VAL502B
• A-C: ALA127A, ALA127C, ALA133A, ALA133C, ALA211A, ALA211C, ALA223A, ALA223C, ALA430A, ALA430C, ALA473A, ALA473C, ALA474A, ALA474C, ALA475A, ALA475C, ALA476A, ALA476C, ALA485A, ALA485C, ALA495A, ALA495C, ALA498A, ALA498C, ALA501A, ALA525A, ALA525C, ARG151A, ARG151C, ARG154A, ARG154C, ARG206A, ARG206C, ARG247A, ARG247C, ARG426A, ARG426C, ARG511A, ARG511C, ARG512A, ARG512C, ARG678A, ARG678C, ARG679A, ARG679C, ASN158A, ASN158C, ASN445A, ASN445C, ASN486A, ASN486C, ASN499A, ASN499C, ASN503A, ASN503C, ASN694A, ASN694C, ASP126A, ASP126C, ASP214A, ASP214C, ASP230A, ASP230C, ASP471A, ASP471C, ASP518A, ASP518C, ASP681A, ASP681C, CYS140A, CYS140C, CYS455A, CYS455C, CYS467A, CYS467C, GLN131A, GLN131C, GLN138A, GLN138C, GLN493A, GLN493C, GLN500A, GLN500C, GLN687A, GLN687C, GLU125A, GLU125C, GLU136A, GLU136C, GLU157A, GLU157C, GLU163A, GLU163C, GLU241A, GLU241C, GLU423A, GLU423C, GLU480A, GLU480C, GLU496A, GLU496C, GLU515A, GLU515C, GLU688A, GLU688C, GLU700A, GLU700C, GLY141A, GLY141C, GLY153A, GLY153C, GLY155A, GLY155C, GLY207A, GLY207C, GLY213A, GLY213C, GLY227A, GLY227C, GLY469A, GLY469C, GLY482A, GLY482C, GLY680A, GLY680C, GLY685A, GLY685C, GLY692A, GLY692C, HIS137A, HIS137C, HIS228A, HIS228C, HIS234A, HIS234C, HIS466A, HIS466C, HIS483A, HIS483C, HIS491A, HIS491C, ILE128A, ILE128C, ILE202A, ILE202C, ILE209A, ILE209C, ILE243A, ILE243C, ILE472A, ILE472C, ILE508A, ILE508C, ILE691A, ILE691C, ILE698A, ILE698C, LEU130A, LEU130C, LEU134A, LEU134C, LEU135A, LEU135C, LEU139A, LEU139C, LEU143A, LEU143C, LEU152A, LEU152C, LEU156A, LEU156C, LEU160A, LEU160C, LEU162A, LEU162C, LEU205A, LEU205C, LEU215A, LEU215C, LEU244C, LEU260A, LEU260C, LEU266C, LEU444A, LEU444C, LEU463A, LEU463C, LEU470A, LEU470C, LEU481A, LEU481C, LEU484A, LEU484C, LEU505A, LEU505C, LEU507A, LEU507C, LEU520A, LEU520C, LEU522A, LEU522C, LEU523A, LEU523C, LEU684A, LEU684C, LYS132A, LYS132C, LYS232A, LYS232C, LYS240A, LYS240C, LYS242A, LYS242C, LYS434A, LYS434C, LYS468A, LYS468C, LYS686A, LYS686C, LYS697A, LYS697C, LYS703A, LYS703C, PHE147A, PHE147C, PHE150A, PHE150C, PHE437A, PHE437C, PHE683A, PHE683C, PRO144A, PRO144C, PRO161A, PRO161C, PRO204A, PRO204C, PRO217A, PRO217C, PRO229A, PRO229C, PRO461A, PRO461C, PRO487A, PRO487C, PRO494A, PRO494C, SER129A, SER129C, SER145A, SER145C, SER146A, SER146C, SER149A, SER149C, SER159A, SER159C, SER210A, SER210C, SER212A, SER212C, SER216A, SER216C, SER226A, SER226C, SER231A, SER231C, SER462A, SER462C, SER464A, SER464C, SER479A, SER479C, SER509A, SER509C, SER516A, SER516C, SER521A, SER521C, SER693A, SER693C, SER696A, SER696C, THR208A, THR208C, THR438A, THR438C, THR441A, THR441C, THR478A, THR478C, THR489A, THR489C, THR490A, THR490C, THR514A, THR514C, THR526A, THR526C, THR690A, THR690C, TYR220A, TYR220C, TYR245A, TYR245C, TYR465A, TYR465C, TYR477A, TYR477C, TYR529A, TYR529C, TYR699A, TYR699C, VAL142A, VAL142C, VAL164A, VAL164C, VAL165A, VAL165C, VAL203A, VAL203C, VAL233A, VAL233C, VAL235A, VAL235C, VAL236A, VAL236C, VAL488A, VAL488C, VAL492A, VAL492C, VAL519A, VAL519C, VAL682A, VAL682C, VAL689A, VAL689C, VAL695A, VAL695C
• A-D: ALA446A, ALA446D, ALA495A, ALA495D, ALA498A, ALA498D, ALA501A, ALA501D, ALA563A, ALA563D, ALA600A, ALA600D, ALA604A, ALA604D, ALA605A, ALA605D, ALA620A, ALA620D, ALA621A, ALA621D, ALA624A, ALA624D, ARG362A, ARG362D, ARG584A, ARG584D, ARG596A, ARG596D, ASN445A, ASN445D, ASN486A, ASN486D, ASN589A, ASN589D, ASN623A, ASN623D, ASP354A, ASP354D, ASP460A, ASP460D, ASP592A, ASP592D, ASP599A, ASP599D, GLN493A, GLN493D, GLN587A, GLN587D, GLU355A, GLU355D, GLU586A, GLU610A, GLU610D, GLY356A, GLY356D, GLY447A, GLY447D, GLY606A, GLY606D, HIS483A, HIS483D, HIS491A, HIS491D, HIS598A, HIS598D, ILE357A, ILE357D, ILE472A, ILE472D, LEU358D, LEU463A, LEU463D, LEU569A, LEU569D, LEU573A, LEU573D, LEU585A, LEU585D, LEU593A, LEU593D, LEU612A, LEU612D, LEU617A, LEU617D, LEU619A, LEU619D, LYS434A, LYS434D, LYS583A, LYS583D, LYS626A, LYS626D, PHE437D, PHE560A, PHE560D, PHE601A, PHE601D, PHE603A, PHE603D, PRO461A, PRO461D, PRO487A, PRO487D, PRO494A, PRO494D, PRO595A, PRO595D, SER454A, SER454D, SER462A, SER462D, SER590A, SER590D, SER602A, SER602D, SER613A, SER613D, SER614A, SER614D, SER616A, SER616D, SER618A, SER618D, THR489A, THR489D, THR490A, THR490D, THR580A, THR580D, THR588A, THR588D, THR607A, THR607D, THR615A, THR615D, TRP625A, TRP625D, TYR363A, TYR363D, TYR465A, TYR465D, TYR591A, TYR591D, VAL488A, VAL488D, VAL492A, VAL492D, VAL594A, VAL594D, VAL608A, VAL608D, VAL609A, VAL609D, VAL611A, VAL611D, VAL622A, VAL622D, VAL627A, VAL627D
• B-C: ALA446B, ALA446C, ALA495B, ALA495C, ALA498B, ALA498C, ALA501B, ALA501C, ALA563B, ALA563C, ALA600B, ALA600C, ALA604B, ALA604C, ALA605B, ALA605C, ALA620B, ALA620C, ALA621B, ALA621C, ALA624B, ALA624C, ARG362B, ARG362C, ARG584B, ARG584C, ARG596B, ARG596C, ASN445B, ASN445C, ASN486B, ASN486C, ASN589B, ASN589C, ASN623B, ASN623C, ASP354B, ASP354C, ASP460B, ASP460C, ASP592B, ASP592C, ASP599B, ASP599C, GLN493B, GLN493C, GLN587B, GLN587C, GLU355B, GLU355C, GLU586C, GLU610B, GLU610C, GLY356B, GLY356C, GLY447B, GLY447C, GLY606B, GLY606C, HIS483B, HIS483C, HIS491B, HIS491C, HIS598B, HIS598C, ILE357B, ILE357C, ILE472B, ILE472C, LEU358B, LEU358C, LEU463B, LEU569B, LEU569C, LEU573B, LEU573C, LEU593B, LEU593C, LEU612B, LEU612C, LEU617B, LEU617C, LEU619B, LEU619C, LYS434B, LYS434C, LYS468B, LYS468C, LYS583B, LYS583C, LYS626B, LYS626C, PHE437B, PHE437C, PHE560B, PHE560C, PHE601B, PHE601C, PHE603B, PHE603C, PRO461B, PRO461C, PRO487B, PRO487C, PRO494B, PRO494C, PRO595B, PRO595C, SER454B, SER454C, SER462B, SER462C, SER479B, SER590B, SER590C, SER602B, SER602C, SER613B, SER613C, SER614B, SER614C, SER616B, SER616C, SER618B, SER618C, THR489B, THR489C, THR490B, THR490C, THR580B, THR580C, THR588B, THR588C, THR607B, THR607C, THR615B, THR615C, TRP625B, TRP625C, TYR363B, TYR363C, TYR465B, TYR465C, TYR591B, TYR591C, VAL488B, VAL488C, VAL492B, VAL492C, VAL594B, VAL594C, VAL608B, VAL608C, VAL609B, VAL609C, VAL611B, VAL611C, VAL622B, VAL622C, VAL627B, VAL627C
• B-D: ALA127B, ALA127D, ALA133B, ALA133D, ALA211B, ALA211D, ALA223B, ALA223D, ALA430B, ALA430D, ALA457D, ALA473B, ALA473D, ALA474B, ALA474D, ALA475B, ALA475D, ALA476B, ALA476D, ALA485B, ALA485D, ALA495B, ALA495D, ALA498B, ALA498D, ALA525B, ALA525D, ARG151B, ARG151D, ARG154B, ARG154D, ARG206B, ARG206D, ARG247B, ARG247D, ARG426B, ARG426D, ARG511B, ARG511D, ARG512B, ARG512D, ARG678B, ARG678D, ARG679B, ARG679D, ASN158B, ASN158D, ASN445B, ASN445D, ASN486B, ASN486D, ASN499B, ASN499D, ASN503B, ASN503D, ASN694B, ASN694D, ASP126B, ASP126D, ASP148D, ASP214B, ASP214D, ASP230B, ASP230D, ASP471B, ASP471D, ASP518B, ASP518D, ASP681B, ASP681D, CYS140B, CYS140D, CYS455B, CYS455D, CYS467B, CYS467D, GLN131B, GLN131D, GLN138B, GLN138D, GLN493B, GLN493D, GLN500B, GLN500D, GLN687B, GLN687D, GLU125B, GLU125D, GLU136B, GLU136D, GLU157B, GLU157D, GLU163B, GLU163D, GLU241B, GLU241D, GLU423B, GLU423D, GLU480B, GLU480D, GLU496B, GLU496D, GLU515B, GLU515D, GLU688B, GLU688D, GLU700B, GLU700D, GLY141B, GLY141D, GLY153B, GLY153D, GLY155B, GLY155D, GLY207B, GLY207D, GLY213B, GLY213D, GLY227B, GLY227D, GLY469B, GLY469D, GLY482B, GLY482D, GLY680B, GLY680D, GLY685B, GLY685D, GLY692B, GLY692D, HIS137B, HIS137D, HIS228B, HIS228D, HIS234B, HIS234D, HIS466B, HIS466D, HIS483B, HIS483D, HIS491B, HIS491D, ILE128B, ILE128D, ILE202B, ILE202D, ILE209B, ILE209D, ILE243B, ILE243D, ILE472B, ILE472D, ILE508B, ILE508D, ILE691B, ILE691D, ILE698B, ILE698D, LEU130B, LEU130D, LEU134B, LEU134D, LEU135B, LEU135D, LEU139B, LEU139D, LEU143B, LEU143D, LEU152B, LEU152D, LEU156B, LEU156D, LEU160B, LEU160D, LEU162B, LEU162D, LEU205B, LEU205D, LEU215B, LEU215D, LEU260B, LEU260D, LEU266B, LEU266D, LEU444B, LEU444D, LEU463B, LEU463D, LEU470B, LEU470D, LEU481B, LEU481D, LEU484B, LEU484D, LEU505B, LEU505D, LEU507B, LEU507D, LEU520B, LEU520D, LEU522B, LEU522D, LEU523B, LEU523D, LEU684B, LEU684D, LYS132B, LYS132D, LYS232B, LYS232D, LYS240B, LYS240D, LYS242B, LYS242D, LYS434B, LYS434D, LYS468B, LYS468D, LYS686B, LYS686D, LYS697B, LYS697D, LYS703B, LYS703D, PHE147B, PHE147D, PHE150B, PHE150D, PHE437B, PHE437D, PHE683B, PHE683D, PRO144B, PRO144D, PRO161B, PRO161D, PRO204B, PRO204D, PRO217B, PRO217D, PRO229B, PRO229D, PRO461B, PRO461D, PRO487B, PRO487D, PRO494B, PRO494D, SER129B, SER129D, SER145B, SER145D, SER146B, SER146D, SER149B, SER149D, SER159B, SER159D, SER210B, SER210D, SER212B, SER212D, SER216B, SER216D, SER226B, SER226D, SER231B, SER231D, SER462B, SER462D, SER464B, SER464D, SER479B, SER479D, SER509B, SER509D, SER516B, SER516D, SER521B, SER521D, SER693B, SER693D, SER696B, SER696D, THR208B, THR208D, THR438B, THR438D, THR441B, THR441D, THR478B, THR478D, THR489B, THR489D, THR490B, THR490D, THR514B, THR514D, THR526B, THR526D, THR690B, THR690D, TYR220B, TYR220D, TYR245B, TYR245D, TYR465B, TYR465D, TYR477B, TYR477D, TYR529B, TYR529D, TYR699B, TYR699D, VAL142B, VAL142D, VAL164B, VAL164D, VAL165B, VAL165D, VAL203B, VAL203D, VAL233B, VAL233D, VAL235B, VAL235D, VAL236B, VAL236D, VAL488B, VAL488D, VAL492B, VAL492D, VAL519B, VAL519D, VAL682B, VAL682D, VAL689B, VAL689D, VAL695B, VAL695D
• C-D: ALA211C, ALA211D, ALA26C, ALA26D, ALA276C, ALA276D, ALA382C, ALA382D, ALA384C, ALA384D, ALA390C, ALA390D, ALA415C, ALA415D, ALA416C, ALA416D, ALA417C, ALA417D, ALA419C, ALA419D, ALA430C, ALA430D, ALA485C, ALA485D, ALA495C, ALA495D, ALA498C, ALA498D, ALA501C, ALA501D, ALA506C, ALA506D, ARG178C, ARG178D, ARG320C, ARG320D, ARG359C, ARG359D, ARG362C, ARG362D, ARG366C, ARG366D, ARG426C, ARG426D, ASN270C, ASN270D, ASN397C, ASN397D, ASN404C, ASN404D, ASN412C, ASN412D, ASN420C, ASN420D, ASN436C, ASN436D, ASN445C, ASN445D, ASN486C, ASN486D, ASN499C, ASN499D, ASN503C, ASN503D, ASP317C, ASP317D, ASP361C, ASP361D, ASP378C, ASP378D, ASP396C, ASP396D, ASP401C, ASP401D, GLN325C, GLN325D, GLN360C, GLN360D, GLN370C, GLN370D, GLN392C, GLN392D, GLN414C, GLN414D, GLN41D, GLN431C, GLN431D, GLN439C, GLN439D, GLN493C, GLN493D, GLN500C, GLN500D, GLU346C, GLU346D, GLU347C, GLU348D, GLU389C, GLU389D, GLU403C, GLU403D, GLU423C, GLU423D, GLU442C, GLU442D, GLU496C, GLU496D, GLY179C, GLY179D, GLY213C, GLY213D, GLY271C, GLY271D, GLY309C, GLY309D, GLY373C, GLY373D, GLY391C, GLY391D, GLY410C, GLY410D, GLY411C, GLY411D, GLY428C, GLY428D, GLY433C, GLY433D, GLY482C, GLY482D, HIS180C, HIS180D, HIS307C, HIS307D, HIS312C, HIS312D, HIS316C, HIS316D, HIS322C, HIS322D, HIS345D, HIS36C, HIS381C, HIS381D, HIS383D, HIS408C, HIS408D, HIS409C, HIS409D, HIS483C, HIS483D, HIS491C, HIS491D, ILE209C, ILE209D, ILE326C, ILE326D, ILE380C, ILE380D, ILE388C, ILE388D, ILE400C, ILE400D, ILE432C, ILE432D, LEU215C, LEU215D, LEU266C, LEU266D, LEU30C, LEU30D, LEU315C, LEU315D, LEU358C, LEU358D, LEU365C, LEU365D, LEU372C, LEU372D, LEU375C, LEU375D, LEU379C, LEU379D, LEU37C, LEU386C, LEU386D, LEU399C, LEU399D, LEU427C, LEU427D, LEU429C, LEU429D, LEU435C, LEU435D, LEU481C, LEU481D, LEU484C, LEU484D, LEU505C, LEU505D, LYS405C, LYS424C, LYS424D, LYS434C, LYS434D, PHE311C, PHE311D, PHE314C, PHE314D, PHE413C, PHE413D, PHE437C, PHE437D, PRO313C, PRO313D, PRO321C, PRO321D, PRO323C, PRO323D, PRO364C, PRO364D, PRO369C, PRO369D, PRO374C, PRO374D, PRO38C, PRO398C, PRO398D, PRO487C, PRO487D, PRO494C, PRO494D, SER175C, SER175D, SER181C, SER181D, SER210C, SER210D, SER212C, SER212D, SER275C, SER275D, SER310C, SER310D, SER35C, SER368C, SER368D, SER377C, SER377D, SER393C, SER393D, SER407C, SER407D, SER479C, SER479D, SER504C, SER504D, SER97C, THR272C, THR272D, THR319C, THR319D, THR324C, THR324D, THR367C, THR367D, THR387C, THR387D, THR394C, THR394D, THR395C, THR395D, THR39C, THR39D, THR406C, THR406D, THR40C, THR40D, THR421C, THR421D, THR438C, THR438D, THR441C, THR441D, THR478C, THR478D, THR489C, THR489D, THR490C, THR490D, TRP371C, TRP371D, TYR363C, TYR363D, TYR65C, TYR65D, VAL318C, VAL318D, VAL349D, VAL376C, VAL376D, VAL385C, VAL385D, VAL402C, VAL402D, VAL418C, VAL418D, VAL42D, VAL488C, VAL488D, VAL492C, VAL492D, VAL502C, VAL502D