1Y2D

catalytic domain of human phosphodiesterase 4d in complex with 1-(4- methoxy-phenyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 83
  • Norm. En. per Res.: -3.8113
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.5078	-85.695	-190.132	-316.3347	83	10	4	7353	6	20	9

Interface residues

• A-B: ALA220A, ALA220B, ALA235A, ALA235B, ARG257A, ARG257B, ARG261A, ARG261B, ASN214A, ASN214B, ASN216A, ASN216B, ASN224A, ASN224B, ASN231A, ASN231B, ASP225A, ASP225B, ASP266A, ASP266B, GLN210A, GLN210B, GLN242A, GLN242B, GLN258A, GLN258B, GLU218A, GLU218B, GLU230A, GLU230B, GLY237A, GLY237B, HIS232A, HIS232B, HIS233A, HIS233B, ILE199A, ILE199B, ILE213A, ILE213B, ILE265A, ILE265B, LEU212B, LEU219A, LEU219B, LEU221A, LEU221B, LEU229A, LEU229B, LEU234A, LEU234B, LEU240A, LEU240B, LEU241A, LEU241B, LEU269A, LEU269B, LYS239A, LYS239B, LYS254A, LYS262A, LYS262B, MET222A, MET222B, MET352B, PHE238A, PHE238B, SER217A, SER217B, SER226A, SER226B, SER227A, SER227B, TYR223A, TYR223B, VAL228A, VAL228B, VAL236A, VAL236B, VAL264A, VAL264B, VAL268A, VAL268B