1XTV

sulfolobus solfataricus uracil phosphoribosyltransferase with uridine 5'-monophosphate (ump) bound to half of the subunits

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 169
  • Norm. En. per Res.: -3.848
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-29.7426	-9.4852	-526.504	-565.7318	170	54	15	22123	2	52	37
A-C	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	2
A-D	-47.1231	-10.8808	-306.897	-364.9009	110	12	7	12008	2	32	33
B-C	-26.6537	0.0975	-304.939	-331.4952	108	19	6	12051	2	31	29
B-D	0.0	0.0	-0.0075	-0.0075	2	0	0	8	0	0	2
C-D	-108.3703	-27.2584	-514.686	-650.3147	169	37	15	21442	7	49	40
C-H	-9.4511	-5.8542	-12.026	-27.3314	16	1	0	611	0	5	5
D-G	-9.9517	-5.9123	-12.5103	-28.3744	16	1	0	627	0	5	5
D-H	-28.9367	50.4274	-136.883	-115.3924	86	20	3	6796	0	34	25
E-F	-67.3104	-10.4502	-521.706	-599.4666	171	61	15	22247	2	51	38
E-H	-46.01	-10.0945	-309.022	-365.1265	112	13	7	11989	2	32	33
F-G	-26.2505	-0.6139	-300.231	-327.0954	108	17	6	11873	2	31	29
F-H	0.0	0.0	-0.0075	-0.0075	2	0	0	8	0	0	2
G-H	-84.6841	-28.053	-514.538	-627.2752	170	40	15	21465	7	49	40

Interface residues

• A-B: ALA210A, ALA210B, ALA92A, ALA92B, ARG19A, ARG19B, ARG213A, ARG213B, ARG34A, ARG34B, ARG37A, ARG37B, ASN198A, ASN198B, ASN27A, ASN27B, ASN31B, ASN45A, ASN45B, ASN71A, ASN71B, ASP194A, ASP194B, ASP209A, ASP209B, ASP20A, ASP20B, ASP212A, ASP212B, ASP48A, ASP48B, ASP66A, ASP66B, ASP69A, ASP69B, ASP7A, ASP7B, GLN17A, GLN17B, GLU196A, GLU196B, GLU42A, GLU42B, GLU50A, GLU50B, GLU53A, GLU53B, GLU55A, GLU55B, GLY201A, GLY201B, GLY206A, GLY206B, GLY208A, GLY208B, GLY40A, GLY40B, GLY59A, GLY59B, GLY64A, GLY64B, HIS13A, HIS13B, ILE10A, ILE10B, ILE14A, ILE14B, ILE170A, ILE170B, ILE203A, ILE203B, ILE38A, ILE38B, ILE43A, ILE43B, ILE51A, ILE51B, ILE67A, ILE67B, ILE6A, ILE6B, ILE73A, LEU12A, LEU12B, LEU15A, LEU15B, LEU18A, LEU18B, LEU197A, LEU197B, LEU204A, LEU204B, LEU207A, LEU207B, LEU35A, LEU35B, LEU39A, LEU39B, LEU47A, LEU47B, LEU58A, LEU58B, LEU70A, LEU70B, LYS200A, LYS200B, LYS21A, LYS21B, LYS30A, LYS30B, LYS61A, LYS61B, LYS63A, LYS63B, LYS8A, LYS8B, LYS91A, LYS91B, LYS95A, LYS95B, MET142A, MET142B, PHE28A, PHE28B, PHE93A, PHE93B, PRO195A, PRO195B, PRO205A, PRO205B, PRO57A, PRO57B, PRO94A, PRO94B, PRO9A, PRO9B, SER44A, SER44B, THR11A, THR11B, THR16A, THR16B, THR23A, THR23B, THR46A, THR46B, THR56A, THR56B, THR62A, THR62B, THR68A, THR68B, TYR202A, TYR202B, TYR22A, TYR22B, TYR41A, TYR41B, TYR49A, TYR49B, VAL33A, VAL33B, VAL52A, VAL52B, VAL54A, VAL54B, VAL60A, VAL60B, VAL65A, VAL65B
• A-C: LYS30A, LYS30C
• A-D: ALA103A, ALA103D, ALA210A, ALA210D, ALA214A, ALA214D, ALA81A, ALA81D, ALA82A, ALA82D, ALA96A, ALA96D, ARG105A, ARG105D, ARG213A, ARG213D, ARG29A, ARG29D, ARG37D, ARG80A, ARG80D, ARG97A, ARG97D, ASN27A, ASN71A, ASN71D, ASN77A, ASN77D, ASP128A, ASP128D, ASP209A, ASP209D, ASP212A, ASP212D, ASP24A, ASP24D, GLN25A, GLN25D, GLN98A, GLN98D, GLU107A, GLU87A, GLU87D, GLY102A, GLY102D, GLY211A, GLY211D, GLY216A, GLY216D, GLY88D, GLY99A, GLY99D, ILE101A, ILE101D, ILE121A, ILE121D, ILE126A, ILE126D, ILE26A, ILE26D, ILE73A, ILE73D, ILE75A, ILE75D, ILE76A, ILE76D, ILE78A, ILE78D, LEU79A, LEU79D, LEU90A, LEU90D, LYS124A, LYS124D, LYS125A, LYS125D, LYS30D, LYS91A, LYS91D, LYS95A, LYS95D, PHE215A, PHE215D, PHE93A, PHE93D, PRO127A, PRO127D, PRO84A, PRO84D, PRO94A, PRO94D, SER104A, SER104D, TYR120A, TYR120D, TYR122A, TYR122D, TYR123A, TYR123D, TYR202D, VAL100A, VAL100D, VAL33A, VAL33D, VAL74A, VAL74D, VAL83A, VAL83D, VAL86A, VAL86D
• B-C: ALA103B, ALA103C, ALA210B, ALA210C, ALA214B, ALA214C, ALA81B, ALA81C, ALA82C, ALA96B, ALA96C, ARG130B, ARG213B, ARG213C, ARG29B, ARG29C, ARG37B, ARG37C, ARG80B, ARG80C, ARG97B, ARG97C, ASN27C, ASN71B, ASN71C, ASN77B, ASN77C, ASP128B, ASP128C, ASP209B, ASP209C, ASP212B, ASP212C, ASP24B, ASP24C, GLN25B, GLN25C, GLN98B, GLN98C, GLU87B, GLU87C, GLY102B, GLY102C, GLY211B, GLY211C, GLY216B, GLY216C, GLY88B, GLY99B, GLY99C, ILE101B, ILE101C, ILE121B, ILE126B, ILE126C, ILE26B, ILE26C, ILE73B, ILE73C, ILE75B, ILE75C, ILE76B, ILE76C, ILE78B, ILE78C, LEU79B, LEU79C, LEU90B, LEU90C, LYS124B, LYS124C, LYS125B, LYS125C, LYS30B, LYS30C, LYS91B, LYS91C, LYS95B, LYS95C, PHE215B, PHE215C, PHE93B, PHE93C, PRO127B, PRO127C, PRO84B, PRO84C, PRO94B, PRO94C, SER104B, SER104C, TYR120B, TYR120C, TYR122B, TYR122C, TYR123B, TYR123C, TYR202C, VAL100B, VAL100C, VAL33B, VAL33C, VAL74B, VAL74C, VAL83B, VAL83C, VAL86B, VAL86C
• B-D: LYS30B, LYS30D
• C-D: ALA210C, ALA210D, ALA92C, ALA92D, ARG19C, ARG19D, ARG213C, ARG213D, ARG34C, ARG34D, ARG37C, ARG37D, ASN198C, ASN198D, ASN27C, ASN27D, ASN31D, ASN45C, ASN45D, ASN71C, ASN71D, ASP194C, ASP194D, ASP209C, ASP209D, ASP20C, ASP20D, ASP212C, ASP212D, ASP48C, ASP48D, ASP66C, ASP66D, ASP69C, ASP69D, ASP7C, ASP7D, GLN17C, GLN17D, GLU196C, GLU196D, GLU42C, GLU42D, GLU50C, GLU50D, GLU53C, GLU53D, GLU55C, GLU55D, GLY201C, GLY201D, GLY206C, GLY206D, GLY208C, GLY208D, GLY36C, GLY40C, GLY40D, GLY59C, GLY59D, GLY64C, GLY64D, GLY88C, HIS13C, HIS13D, ILE10C, ILE10D, ILE14C, ILE14D, ILE170C, ILE170D, ILE203C, ILE203D, ILE38C, ILE38D, ILE43C, ILE43D, ILE51C, ILE51D, ILE67C, ILE67D, ILE6C, ILE6D, ILE73C, LEU12C, LEU12D, LEU15C, LEU15D, LEU18C, LEU18D, LEU197C, LEU197D, LEU204C, LEU204D, LEU207C, LEU207D, LEU35D, LEU39C, LEU39D, LEU47C, LEU47D, LEU58C, LEU58D, LEU70C, LEU70D, LEU90C, LYS200C, LYS200D, LYS21C, LYS21D, LYS30C, LYS30D, LYS61C, LYS61D, LYS63C, LYS63D, LYS8C, LYS8D, LYS91C, LYS91D, LYS95C, LYS95D, MET142C, MET142D, PHE28C, PHE28D, PHE93C, PHE93D, PRO205C, PRO205D, PRO57C, PRO57D, PRO94C, PRO94D, PRO9C, PRO9D, SER44C, SER44D, THR11C, THR11D, THR16C, THR16D, THR23C, THR23D, THR46C, THR46D, THR56C, THR56D, THR62C, THR62D, THR68C, THR68D, TYR202C, TYR202D, TYR22C, TYR22D, TYR41C, TYR41D, TYR49C, TYR49D, VAL33C, VAL52C, VAL52D, VAL54C, VAL54D, VAL60C, VAL60D, VAL65C, VAL65D
• C-H: ALA131H, ASN160H, ASP7C, HIS13C, ILE10C, ILE6C, LEU12C, LYS132H, LYS162H, LYS8C, PHE185H, PRO161H, PRO184H, PRO9C, THR11C, VAL5C
• D-G: ALA131D, ASN160D, ASP7G, HIS13G, ILE10G, ILE6G, LEU12G, LYS132D, LYS162D, LYS8G, PHE185D, PRO161D, PRO184D, PRO9G, THR11G, VAL5G
• D-H: ALA131D, ALA131H, ARG130D, ARG130H, ARG163D, ARG163H, ASN160D, ASN160H, ASN177D, ASN177H, ASN45D, ASN45H, ASP134D, ASP134H, ASP48D, ASP48H, ASP66D, ASP66H, ASP69D, ASP69H, ASP7D, ASP7H, GLU42D, GLU42H, GLU50D, GLU50H, GLY64D, GLY64H, ILE186D, ILE186H, ILE193D, ILE193H, ILE51D, ILE51H, ILE67D, ILE67H, ILE6D, ILE6H, LEU180D, LEU180H, LEU188D, LEU188H, LEU3D, LEU3H, LEU47D, LEU47H, LYS132D, LYS132H, LYS162D, LYS162H, LYS63D, LYS63H, LYS8D, LYS8H, PHE185D, PHE185H, PHE189D, PHE189H, PRO161D, PRO161H, PRO184D, PRO184H, PRO2D, PRO2H, SER181D, SER181H, THR46D, THR46H, THR68D, THR68H, TYR165D, TYR165H, TYR187D, TYR187H, TYR49D, TYR49H, TYR4D, TYR4H, VAL133D, VAL133H, VAL176D, VAL176H, VAL5D, VAL5H, VAL65D, VAL65H
• E-F: ALA210E, ALA210F, ALA92E, ALA92F, ARG19E, ARG19F, ARG213E, ARG213F, ARG34E, ARG34F, ARG37E, ARG37F, ASN198E, ASN198F, ASN27E, ASN27F, ASN31F, ASN45E, ASN45F, ASN71E, ASN71F, ASP194E, ASP194F, ASP209E, ASP209F, ASP20E, ASP20F, ASP212E, ASP212F, ASP48E, ASP48F, ASP66E, ASP66F, ASP69E, ASP69F, ASP7E, ASP7F, GLN17E, GLN17F, GLU196E, GLU196F, GLU42E, GLU42F, GLU50E, GLU50F, GLU53E, GLU53F, GLU55E, GLU55F, GLY201E, GLY201F, GLY206E, GLY206F, GLY208E, GLY208F, GLY40E, GLY40F, GLY59E, GLY59F, GLY64E, GLY64F, HIS13E, HIS13F, ILE10E, ILE10F, ILE14E, ILE14F, ILE170E, ILE170F, ILE203E, ILE203F, ILE38E, ILE38F, ILE43E, ILE43F, ILE51E, ILE51F, ILE67E, ILE67F, ILE6E, ILE6F, ILE73E, LEU12E, LEU12F, LEU15E, LEU15F, LEU18E, LEU18F, LEU197E, LEU197F, LEU204E, LEU204F, LEU207E, LEU207F, LEU35E, LEU35F, LEU39E, LEU39F, LEU47E, LEU47F, LEU58E, LEU58F, LEU70E, LEU70F, LYS200E, LYS200F, LYS21E, LYS21F, LYS30E, LYS30F, LYS61E, LYS61F, LYS63E, LYS63F, LYS8E, LYS8F, LYS91E, LYS91F, LYS95E, LYS95F, MET142E, MET142F, PHE28E, PHE28F, PHE93E, PHE93F, PRO195E, PRO195F, PRO205E, PRO205F, PRO57E, PRO57F, PRO94E, PRO94F, PRO9E, PRO9F, SER44E, SER44F, THR11E, THR11F, THR16E, THR16F, THR23E, THR23F, THR46E, THR46F, THR56E, THR56F, THR62E, THR62F, THR68E, THR68F, TYR202E, TYR202F, TYR22E, TYR22F, TYR41E, TYR41F, TYR49E, TYR49F, VAL191E, VAL33E, VAL33F, VAL52E, VAL52F, VAL54E, VAL54F, VAL60E, VAL60F, VAL65E, VAL65F
• E-H: ALA103E, ALA103H, ALA210E, ALA210H, ALA214E, ALA214H, ALA81E, ALA81H, ALA82E, ALA82H, ALA96E, ALA96H, ARG105E, ARG105H, ARG213E, ARG213H, ARG29E, ARG29H, ARG37H, ARG80E, ARG80H, ARG97E, ARG97H, ASN27E, ASN27H, ASN71E, ASN71H, ASN77E, ASN77H, ASP128E, ASP128H, ASP209E, ASP209H, ASP212E, ASP212H, ASP24E, ASP24H, GLN25E, GLN25H, GLN98E, GLN98H, GLU107E, GLU87E, GLU87H, GLY102E, GLY102H, GLY211E, GLY211H, GLY216E, GLY216H, GLY88H, GLY99E, GLY99H, ILE101E, ILE101H, ILE121E, ILE121H, ILE126E, ILE126H, ILE26E, ILE26H, ILE73E, ILE73H, ILE75E, ILE75H, ILE76E, ILE76H, ILE78E, ILE78H, LEU79E, LEU79H, LEU90E, LEU90H, LYS124E, LYS124H, LYS125E, LYS125H, LYS30H, LYS91E, LYS91H, LYS95E, LYS95H, PHE215E, PHE215H, PHE93E, PHE93H, PRO127E, PRO127H, PRO84E, PRO84H, PRO94E, PRO94H, SER104E, SER104H, TYR120E, TYR120H, TYR122E, TYR122H, TYR123E, TYR123H, TYR202E, TYR202H, VAL100E, VAL100H, VAL33E, VAL33H, VAL74E, VAL74H, VAL83E, VAL83H, VAL86E, VAL86H
• F-G: ALA103F, ALA103G, ALA210F, ALA210G, ALA214F, ALA214G, ALA81F, ALA81G, ALA82G, ALA96F, ALA96G, ARG130F, ARG213F, ARG213G, ARG29F, ARG29G, ARG37F, ARG37G, ARG80F, ARG80G, ARG97F, ARG97G, ASN27G, ASN71F, ASN71G, ASN77F, ASN77G, ASP128F, ASP128G, ASP209F, ASP209G, ASP212F, ASP212G, ASP24F, ASP24G, GLN25F, GLN25G, GLN98F, GLN98G, GLU87F, GLU87G, GLY102F, GLY102G, GLY211F, GLY211G, GLY216F, GLY216G, GLY99F, GLY99G, ILE101F, ILE101G, ILE121F, ILE121G, ILE126F, ILE126G, ILE26F, ILE26G, ILE73F, ILE73G, ILE75F, ILE75G, ILE76F, ILE76G, ILE78F, ILE78G, LEU79F, LEU79G, LEU90F, LEU90G, LYS124F, LYS124G, LYS125F, LYS125G, LYS30F, LYS30G, LYS91F, LYS91G, LYS95F, LYS95G, PHE215F, PHE215G, PHE93F, PHE93G, PRO127F, PRO127G, PRO84F, PRO84G, PRO94F, PRO94G, SER104F, SER104G, TYR120F, TYR120G, TYR122F, TYR122G, TYR123F, TYR123G, TYR202G, VAL100F, VAL100G, VAL33F, VAL33G, VAL74F, VAL74G, VAL83F, VAL83G, VAL86F, VAL86G
• F-H: LYS30F, LYS30H
• G-H: ALA210G, ALA210H, ALA92G, ALA92H, ARG19G, ARG19H, ARG213G, ARG213H, ARG34G, ARG34H, ARG37G, ARG37H, ASN198G, ASN198H, ASN27G, ASN27H, ASN31H, ASN45G, ASN45H, ASN71G, ASN71H, ASP194G, ASP194H, ASP209G, ASP209H, ASP20G, ASP20H, ASP212G, ASP212H, ASP48G, ASP48H, ASP66G, ASP66H, ASP69G, ASP69H, ASP7G, ASP7H, GLN17G, GLN17H, GLU196G, GLU196H, GLU42G, GLU42H, GLU50G, GLU50H, GLU53G, GLU53H, GLU55G, GLU55H, GLY201G, GLY201H, GLY206G, GLY206H, GLY208G, GLY208H, GLY40G, GLY40H, GLY59G, GLY59H, GLY64G, GLY64H, GLY88G, HIS13G, HIS13H, ILE10G, ILE10H, ILE14G, ILE14H, ILE170G, ILE170H, ILE203G, ILE203H, ILE38G, ILE38H, ILE43G, ILE43H, ILE51G, ILE51H, ILE67G, ILE67H, ILE6G, ILE6H, ILE73G, LEU12G, LEU12H, LEU15G, LEU15H, LEU18G, LEU18H, LEU197G, LEU197H, LEU204G, LEU204H, LEU207G, LEU207H, LEU35H, LEU39G, LEU39H, LEU47G, LEU47H, LEU58G, LEU58H, LEU70G, LEU70H, LEU90G, LYS200G, LYS200H, LYS21G, LYS21H, LYS30G, LYS30H, LYS61G, LYS61H, LYS63G, LYS63H, LYS8G, LYS8H, LYS91G, LYS91H, LYS95G, LYS95H, MET142G, MET142H, PHE28G, PHE28H, PHE93G, PHE93H, PRO195G, PRO195H, PRO205G, PRO205H, PRO57G, PRO57H, PRO94G, PRO94H, PRO9G, PRO9H, SER44G, SER44H, THR11G, THR11H, THR16G, THR16H, THR23G, THR23H, THR46G, THR46H, THR56G, THR56H, THR62G, THR62H, THR68G, THR68H, TYR202G, TYR202H, TYR22G, TYR22H, TYR41G, TYR41H, TYR49G, TYR49H, VAL33G, VAL52G, VAL52H, VAL54G, VAL54H, VAL60G, VAL60H, VAL65G, VAL65H