1XQH

crystal structure of a ternary complex of the methyltransferase set9 (also known as set7/9) with a p53 peptide and sah

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 48
  • Norm. En. per Res.: -3.3706
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-19.8154	-12.5726	-122.575	-154.9631	48	4	0	4910	0	15	8
A-E	-52.5745	29.0011	-142.902	-166.4754	63	8	2	5540	0	10	19
E-F	-27.2469	-11.519	-123.024	-161.7899	48	5	0	4879	0	15	9

Interface residues

• A-B: ALA261A, ALA334A, ALA349A, ARG258A, ASN263A, ASN265A, ASP256A, ASP259A, ASP270A, ASP276A, ASP306A, ASP338A, GLN253A, GLU254A, GLU271A, GLU348A, GLY264A, GLY336A, GLY343A, GLY374B, HIS252A, ILE250A, ILE275A, ILE304A, LEU262A, LEU267A, LEU269A, LEU369B, LYS317A, LYS370B, LYS373B, MET307A, PRO341A, PRO342A, PRO350A, SER257A, SER268A, SER371B, THR251A, THR266A, THR273A, TRP260A, TYR305A, TYR335A, TYR337A, VAL255A, VAL274A, VAL333A
• A-E: ARG179A, ARG179E, ARG320A, ARG320E, ASN239A, ASN239E, ASP125A, ASP125E, ASP150A, ASP150E, CYS119A, CYS119E, GLU132A, GLU132E, GLU151A, GLU151E, GLU176A, GLU176E, GLU177A, GLU177E, GLY117A, GLY117E, GLY126A, GLY126E, GLY127A, GLY127E, GLY131A, GLY131E, GLY178A, GLY178E, ILE121A, ILE121E, LEU129A, LEU129E, MET139A, PRO124A, PRO124E, PRO149A, PRO149E, PRO180A, PRO180E, SER128A, SER128E, THR175A, THR175E, THR240A, THR240E, TRP120A, TRP120E, TYR122A, TYR122E, TYR123A, TYR123E, TYR148A, TYR148E, VAL118A, VAL118E, VAL130A, VAL130E, VAL133A, VAL133E, VAL241A, VAL241E
• E-F: ALA261E, ALA334E, ALA349E, ARG258E, ASN263E, ASN265E, ASP256E, ASP259E, ASP270E, ASP276E, ASP306E, ASP338E, GLN253E, GLU254E, GLU271E, GLU348E, GLY264E, GLY336E, GLY343E, GLY374F, HIS252E, ILE250E, ILE275E, ILE304E, LEU262E, LEU267E, LEU269E, LEU369F, LYS317E, LYS370F, LYS373F, MET307E, PRO341E, PRO342E, PRO350E, SER257E, SER268E, SER371F, THR251E, THR266E, THR273E, TRP260E, TYR305E, TYR335E, TYR337E, VAL255E, VAL274E, VAL333E