1XMU

catalytic domain of human phosphodiesterase 4b in complex with roflumilast

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 89
  • Norm. En. per Res.: -3.1619
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-28.4775	-80.0871	-172.847	-281.4116	89	10	4	7518	7	30	17

Interface residues

• A-B: ALA294A, ALA294B, ALA309A, ALA309B, ARG331A, ARG331B, ARG335A, ARG335B, ASN288A, ASN288B, ASN290A, ASN290B, ASN298A, ASN298B, ASN305A, ASN305B, ASP299A, ASP299B, ASP340A, ASP340B, GLN284A, GLN284B, GLN316A, GLN316B, GLN332A, GLN332B, GLU292A, GLU292B, GLU300A, GLU300B, GLU304A, GLU304B, GLU427A, GLU427B, GLY311A, GLY311B, GLY425A, GLY425B, HIS306A, HIS306B, HIS307A, HIS307B, ILE287A, ILE287B, ILE339A, ILE339B, LEU286A, LEU293A, LEU293B, LEU295A, LEU295B, LEU303A, LEU303B, LEU308A, LEU308B, LEU314A, LEU314B, LEU315A, LEU315B, LEU343A, LEU343B, LYS313A, LYS313B, LYS328A, LYS328B, LYS336A, LYS336B, MET296A, MET296B, MET426A, MET426B, PHE312A, PHE312B, SER291A, SER291B, SER301A, SER301B, THR289A, THR289B, TYR297A, TYR297B, VAL302A, VAL302B, VAL310A, VAL310B, VAL338A, VAL338B, VAL342A, VAL342B