1XM2

crystal structure of human prl-1

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: B-F
  • Int. Res.: 63
  • Norm. En. per Res.: -4.8827
• Hub Node: B(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-19.0994	-18.0067	-125.298	-162.4042	50	26	0	5481	2	17	23
A-C	-4.6876	2.0307	-151.347	-154.0039	54	10	0	5735	0	18	25
B-C	-6.1704	-18.3024	-125.577	-150.0498	51	14	0	5615	2	17	24
B-D	-6.5488	36.0885	-33.3595	-3.8198	19	0	0	1466	1	11	8
B-F	-14.2058	-143.5489	-149.855	-307.6097	63	13	3	6599	13	36	43
C-F	-5.3939	25.7928	-32.949	-12.5501	20	2	0	1563	1	11	8
D-E	-6.8061	-13.5087	-148.937	-169.2518	50	18	0	5603	3	18	23
D-F	-5.6796	1.3358	-138.476	-142.8198	52	17	0	5550	1	17	23
E-F	-3.6784	-9.3215	-125.879	-138.8789	48	9	0	5088	0	18	22

Interface residues

• A-B: ALA129B, ALA140B, ARG134B, ARG137B, ARG138B, ARG18A, ARG93A, ASN16A, ASP128B, CYS98A, CYS99A, GLN131B, GLN135A, GLN135B, GLU11A, GLU127B, GLU150B, GLU35A, GLU36A, GLU95A, GLY139B, GLY41A, GLY97A, ILE100A, ILE133B, LEU146B, LEU20A, LEU37A, LYS125B, LYS136A, LYS136B, LYS15A, LYS38A, LYS39A, LYS91A, PHE132A, PHE132B, PHE141B, PHE19A, PHE92A, PRO96A, PRO9A, THR13A, TYR126B, TYR14A, TYR40A, VAL10A, VAL12A, VAL130B, VAL42A
• A-C: ALA129A, ALA140A, ARG134A, ARG137A, ARG138A, ARG18C, ARG93C, ASN16C, ASP128A, CYS98C, CYS99C, GLN131A, GLN135A, GLN135C, GLU11C, GLU127A, GLU150A, GLU35C, GLU36C, GLU94C, GLU95C, GLY139A, GLY41C, GLY97C, ILE100C, ILE133A, LEU108A, LEU146A, LEU20C, LEU37C, LYS125A, LYS136A, LYS136C, LYS15C, LYS32C, LYS38C, LYS39C, LYS91C, PHE132A, PHE132C, PHE141A, PHE19C, PHE92C, PRO96C, PRO9C, THR13C, THR43C, TYR126A, TYR14C, TYR40C, VAL10C, VAL12C, VAL130A, VAL42C
• B-C: ALA129C, ALA140C, ARG134C, ARG137C, ARG138C, ARG18B, ARG93B, ASN16B, ASP128C, CYS98B, CYS99B, GLN131C, GLN135B, GLN135C, GLU11B, GLU127C, GLU150C, GLU35B, GLU36B, GLU95B, GLY139C, GLY41B, GLY97B, ILE100B, ILE133C, LEU108C, LEU146C, LEU147C, LEU20B, LEU37B, LYS125C, LYS136B, LYS136C, LYS15B, LYS38B, LYS39B, PHE132B, PHE132C, PHE141C, PHE19B, PHE92B, PRO96B, PRO9B, THR13B, THR43B, TYR126C, TYR14B, TYR40B, VAL10B, VAL12B, VAL130C
• B-D: ASP54B, GLU150D, GLU59B, GLU61B, GLY62B, LEU146D, LEU147D, LEU57B, LYS144D, LYS151D, LYS60B, SER143D, THR55B, THR56B, TYR126D, TYR148D, TYR152D, VAL58B, VAL65B
• B-F: ARG93B, ARG93F, ASN78F, ASP67B, ASP67F, ASP82B, ASP82F, ASP83B, ASP83F, CYS98B, CYS98F, GLN79B, GLN79F, GLU59B, GLU59F, GLU94B, GLU94F, GLU95B, GLU95F, GLY62B, HIS64B, HIS64F, ILE100B, ILE100F, ILE45B, ILE45F, ILE63B, ILE63F, ILE80B, ILE80F, ILE90B, ILE90F, LEU66B, LEU66F, LEU85B, LEU85F, LEU87B, LEU87F, LYS89B, LYS89F, LYS91B, LYS91F, PHE92B, PHE92F, PRO96B, PRO96F, SER86B, SER86F, THR43B, THR43F, THR44B, THR44F, TRP68B, TRP68F, TRP84B, TRP84F, VAL46B, VAL46F, VAL65B, VAL65F, VAL81F, VAL88B, VAL88F
• C-F: ASP54F, GLU150C, GLU59F, GLU61F, GLY62F, HIS64F, LEU146C, LEU147C, LEU57F, LYS144C, LYS151C, LYS60F, SER143C, THR55F, THR56F, TYR126C, TYR148C, TYR152C, VAL58F, VAL65F
• D-E: ALA129E, ALA140E, ARG134E, ARG137E, ARG138E, ARG18D, ARG93D, ASN16D, ASP128E, CYS98D, CYS99D, GLN131E, GLN135E, GLU11D, GLU127E, GLU150E, GLU35D, GLU36D, GLU95D, GLY139E, GLY41D, GLY97D, ILE100D, ILE133E, LEU108E, LEU146E, LEU20D, LEU37D, LYS125E, LYS136D, LYS136E, LYS15D, LYS38D, LYS39D, PHE132D, PHE132E, PHE141E, PHE19D, PHE92D, PRO96D, PRO9D, THR13D, THR43D, TYR126E, TYR14D, TYR40D, VAL10D, VAL12D, VAL130E, VAL42D
• D-F: ALA129D, ALA140D, ARG134D, ARG137D, ARG138D, ARG18F, ARG93F, ASN16F, ASP128D, CYS98F, CYS99F, GLN131D, GLN135D, GLN135F, GLU11F, GLU127D, GLU150D, GLU35F, GLU36F, GLU94F, GLU95F, GLY139D, GLY41F, GLY97F, ILE100F, ILE133D, LEU146D, LEU147D, LEU20F, LEU37F, LYS125D, LYS136D, LYS136F, LYS15F, LYS38F, LYS39F, LYS91F, PHE132D, PHE132F, PHE141D, PHE19F, PHE92F, PRO96F, PRO9F, THR13F, TYR126D, TYR14D, TYR14F, TYR40F, VAL10F, VAL12F, VAL130D
• E-F: ALA129F, ALA140F, ARG134F, ARG137F, ARG138F, ARG18E, ARG93E, ASN16E, ASP128F, CYS98E, CYS99E, GLN131F, GLN135F, GLU11E, GLU127F, GLU150F, GLU35E, GLU36E, GLU95E, GLY139F, GLY41E, GLY97E, ILE100E, ILE133F, LEU146F, LEU20E, LEU37E, LYS125F, LYS136E, LYS136F, LYS15E, LYS38E, LYS39E, PHE132E, PHE132F, PHE141F, PHE19E, PHE92E, PRO96E, PRO9E, THR13E, TYR126F, TYR14E, TYR40E, VAL10E, VAL12E, VAL130F, VAL42E