1XK8

divalent cation tolerant protein cuta from homo sapiens o60888

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 113
  • Norm. En. per Res.: -3.9227
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-81.9327	-50.8251	-310.511	-443.2688	113	10	18	13372	2	21	12
A-C	-87.1273	-23.9446	-311.629	-422.7009	111	10	18	13188	2	22	10
A-D	0.0	0.0	-17.5266	-17.5266	30	2	0	1217	0	0	2
A-E	0.0	0.0	-0.0154	-0.0154	2	0	0	1	0	0	1
A-F	0.0	6.13	-40.4101	-34.2801	20	0	0	1359	0	0	1
B-C	-81.8161	-28.5369	-311.839	-422.192	110	12	18	12964	2	20	9
B-D	0.0	0.0	-0.0305	-0.0305	2	0	0	2	0	0	1
B-E	0.0	5.0772	-41.701	-36.6238	20	0	0	1400	0	0	1
B-F	0.0	0.0	-16.9796	-16.9796	31	3	0	1153	0	0	1
C-D	0.0	4.5838	-40.7979	-36.2141	20	0	0	1401	0	0	1
C-E	0.0	0.0	-17.3462	-17.3462	31	3	0	1212	0	0	1
C-F	0.0	0.0	-0.0179	-0.0179	2	0	0	1	0	0	1
D-E	-88.4742	-42.9065	-298.902	-430.2827	111	10	18	12968	2	19	6
D-F	-72.3084	5.9314	-287.054	-353.431	112	11	19	12243	0	15	8
E-F	-73.6601	-28.3725	-308.255	-410.2877	110	12	18	13047	1	22	10

Interface residues

• A-B: ALA109B, ALA123B, ALA127A, ALA127B, ALA47A, ALA47B, ALA48A, ALA48B, ALA58A, ALA62A, ALA64A, ALA71A, ALA72A, ARG115B, ARG63A, ARG69A, ASN134A, ASN75A, ASP112B, ASP93B, CYS52B, CYS73A, GLN103B, GLN132A, GLN139A, GLN143A, GLN79A, GLN79B, GLU121B, GLU124B, GLU131A, GLU55A, GLU60A, GLU67A, GLU85B, GLU91B, GLU92B, GLU95B, GLY133A, GLY43A, GLY43B, GLY88B, HIS118B, ILE100A, ILE126B, ILE61A, ILE77A, ILE77B, ILE80A, ILE80B, ILE83B, ILE90B, LEU106B, LEU110B, LEU128A, LEU128B, LEU138A, LEU76A, LEU97A, LEU97B, LYS101A, LYS59A, LYS68A, LYS89B, MET98A, MET98B, MET99A, MET99B, PHE135A, PHE49A, PHE49B, PRO108B, PRO129A, PRO129B, PRO136A, PRO42A, PRO42B, PRO78A, PRO78B, SER104B, SER105B, SER116B, SER44B, SER46A, SER46B, SER82B, THR102A, THR102B, THR111B, THR51B, THR81B, TRP140A, TRP86B, TYR120B, TYR137A, TYR40A, TYR84B, VAL107B, VAL114B, VAL122B, VAL125B, VAL130A, VAL130B, VAL141A, VAL144A, VAL45A, VAL45B, VAL50B, VAL65A, VAL66A, VAL74A, VAL96A, VAL96B
• A-C: ALA109A, ALA123A, ALA127A, ALA127C, ALA47A, ALA47C, ALA48A, ALA48C, ALA58C, ALA62C, ALA64C, ALA71C, ALA72C, ARG115A, ARG63C, ARG69C, ASN134C, ASN75C, ASP112A, ASP93A, CYS52A, CYS73C, GLN103A, GLN132C, GLN139C, GLN79A, GLN79C, GLU121A, GLU124A, GLU131C, GLU55C, GLU60C, GLU67C, GLU85A, GLU91A, GLU92A, GLU95A, GLY133C, GLY43A, GLY43C, GLY88A, HIS118A, ILE100C, ILE126A, ILE61C, ILE77A, ILE77C, ILE80A, ILE80C, ILE83A, ILE90A, LEU106A, LEU110A, LEU128A, LEU128C, LEU138C, LEU76C, LEU97A, LEU97C, LYS101C, LYS59C, LYS68C, LYS89A, MET98A, MET98C, MET99A, MET99C, PHE135C, PHE49A, PHE49C, PRO108A, PRO129A, PRO129C, PRO136C, PRO42A, PRO42C, PRO78A, PRO78C, SER104A, SER105A, SER44A, SER46A, SER46C, SER82A, THR102A, THR102C, THR111A, THR51A, THR81A, TRP140C, TRP86A, TYR120A, TYR137C, TYR40C, TYR84A, VAL107A, VAL114A, VAL122A, VAL125A, VAL130A, VAL130C, VAL141C, VAL144C, VAL45A, VAL45C, VAL50A, VAL65C, VAL66C, VAL74C, VAL96A, VAL96C
• A-D: ALA127A, ALA127D, ARG142A, ARG142D, GLN103A, GLN103D, GLY43A, GLY43D, LEU106A, LEU106D, PRO108A, PRO108D, PRO129A, PRO129D, PRO42A, PRO42D, SER104A, SER104D, SER105A, SER105D, SER44A, SER44D, SER46A, SER46D, TYR40A, TYR40D, VAL107A, VAL107D, VAL41A, VAL41D
• A-E: GLU131A, GLU131E
• A-F: GLN132A, GLN132F, GLU131A, GLU131F, GLY133A, GLY133F, GLY43A, GLY43F, PRO129A, PRO129F, PRO42A, PRO42F, SER44A, SER44F, TYR40A, TYR40F, VAL130A, VAL130F, VAL41A, VAL41F
• B-C: ALA109C, ALA123C, ALA127B, ALA127C, ALA47B, ALA47C, ALA48B, ALA48C, ALA58B, ALA62B, ALA64B, ALA71B, ALA72B, ARG115C, ARG63B, ARG69B, ASN134B, ASN75B, ASP112C, ASP93C, CYS73B, GLN103C, GLN132B, GLN79B, GLN79C, GLU121C, GLU124C, GLU131B, GLU55B, GLU60B, GLU67B, GLU85C, GLU91C, GLU92C, GLU95C, GLY133B, GLY43B, GLY43C, GLY88C, HIS118C, ILE100B, ILE126C, ILE61B, ILE77B, ILE77C, ILE80B, ILE80C, ILE83C, ILE90C, LEU106C, LEU110C, LEU128B, LEU128C, LEU138B, LEU76B, LEU97B, LEU97C, LYS101B, LYS59B, LYS68B, LYS87C, LYS89C, MET98B, MET98C, MET99B, MET99C, PHE135B, PHE49B, PHE49C, PRO108C, PRO129B, PRO129C, PRO136B, PRO42B, PRO42C, PRO78B, PRO78C, SER104C, SER105C, SER116C, SER44C, SER46B, SER46C, SER82C, SER94C, THR102B, THR111C, THR51C, THR81C, TRP140B, TRP86C, TYR120C, TYR137B, TYR40B, TYR84C, VAL107C, VAL114C, VAL122C, VAL125C, VAL130B, VAL130C, VAL141B, VAL144B, VAL45B, VAL45C, VAL50C, VAL65B, VAL66B, VAL74B, VAL96B
• B-D: GLU131B, GLU131D
• B-E: GLN132B, GLN132E, GLU131B, GLU131E, GLY133B, GLY133E, GLY43B, GLY43E, PRO129B, PRO129E, PRO42B, PRO42E, SER44B, SER44E, TYR40B, TYR40E, VAL130B, VAL130E, VAL41B, VAL41E
• B-F: ALA109B, ALA127B, ALA127F, ARG142B, ARG142F, GLN103B, GLN103F, GLY43B, GLY43F, LEU106B, LEU106F, PRO108B, PRO108F, PRO129B, PRO129F, PRO42B, PRO42F, SER104B, SER104F, SER105B, SER105F, SER44B, SER44F, SER46B, SER46F, TYR40B, TYR40F, VAL107B, VAL107F, VAL41B, VAL41F
• C-D: GLN132C, GLN132D, GLU131C, GLU131D, GLY133C, GLY133D, GLY43C, GLY43D, PRO129C, PRO129D, PRO42C, PRO42D, SER44C, SER44D, TYR40C, TYR40D, VAL130C, VAL130D, VAL41C, VAL41D
• C-E: ALA109E, ALA127C, ALA127E, ARG142C, ARG142E, GLN103C, GLN103E, GLY43C, GLY43E, LEU106C, LEU106E, PRO108C, PRO108E, PRO129C, PRO129E, PRO42C, PRO42E, SER104C, SER104E, SER105C, SER105E, SER44C, SER44E, SER46C, SER46E, TYR40C, TYR40E, VAL107C, VAL107E, VAL41C, VAL41E
• C-F: GLU131C, GLU131F
• D-E: ALA109E, ALA123E, ALA127D, ALA127E, ALA47D, ALA47E, ALA48D, ALA48E, ALA58D, ALA62D, ALA64D, ALA71D, ALA72D, ARG115E, ARG63D, ARG69D, ASN134D, ASN75D, ASP112E, ASP93E, CYS52E, CYS73D, GLN103E, GLN132D, GLN139D, GLN79D, GLN79E, GLU121E, GLU124E, GLU131D, GLU55D, GLU60D, GLU67D, GLU85E, GLU91E, GLU92E, GLU95E, GLY133D, GLY43D, GLY43E, GLY88E, HIS118E, ILE100D, ILE126E, ILE61D, ILE77D, ILE77E, ILE80D, ILE80E, ILE83E, ILE90E, LEU106E, LEU110E, LEU128D, LEU128E, LEU138D, LEU76D, LEU97D, LEU97E, LYS101D, LYS59D, LYS68D, LYS89E, MET98D, MET98E, MET99D, MET99E, PHE135D, PHE49D, PHE49E, PRO108E, PRO129D, PRO129E, PRO136D, PRO42D, PRO42E, PRO78D, PRO78E, SER104E, SER105E, SER44E, SER46D, SER46E, SER82E, THR102D, THR102E, THR111E, THR51E, THR81E, TRP140D, TRP86E, TYR120E, TYR137D, TYR40D, TYR84E, VAL107E, VAL114E, VAL122E, VAL125E, VAL130D, VAL130E, VAL141D, VAL144D, VAL45D, VAL45E, VAL50E, VAL65D, VAL66D, VAL74D, VAL96D, VAL96E
• D-F: ALA109D, ALA123D, ALA127D, ALA127F, ALA47D, ALA47F, ALA48D, ALA48F, ALA58F, ALA62F, ALA64F, ALA71F, ALA72F, ARG115D, ARG63F, ARG69F, ASN134F, ASN75F, ASP112D, ASP93D, CYS52D, CYS73F, GLN103D, GLN132F, GLN139F, GLN79D, GLN79F, GLU121D, GLU124D, GLU131F, GLU55F, GLU60F, GLU67F, GLU85D, GLU91D, GLU92D, GLU95D, GLY133F, GLY43D, GLY43F, GLY88D, HIS118D, ILE100F, ILE126D, ILE61F, ILE77D, ILE77F, ILE80D, ILE80F, ILE83D, ILE90D, LEU106D, LEU110D, LEU128D, LEU128F, LEU138F, LEU76F, LEU97D, LEU97F, LYS101F, LYS59F, LYS68F, LYS87D, LYS89D, MET98D, MET98F, MET99D, MET99F, PHE135F, PHE49D, PHE49F, PRO108D, PRO129D, PRO129F, PRO136F, PRO42D, PRO42F, PRO78D, PRO78F, SER104D, SER105D, SER44D, SER46D, SER46F, SER82D, THR102D, THR102F, THR111D, THR51D, THR81D, TRP140F, TRP86D, TYR120D, TYR137F, TYR40F, TYR84D, VAL107D, VAL114D, VAL122D, VAL125D, VAL130D, VAL130F, VAL141F, VAL144F, VAL45D, VAL45F, VAL50D, VAL65F, VAL66F, VAL74F, VAL96D, VAL96F
• E-F: ALA109F, ALA123F, ALA127E, ALA127F, ALA47E, ALA47F, ALA48E, ALA48F, ALA58E, ALA62E, ALA64E, ALA71E, ALA72E, ARG115F, ARG63E, ARG69E, ASN134E, ASN75E, ASP112F, ASP93F, CYS73E, GLN103F, GLN132E, GLN139E, GLN79E, GLN79F, GLU121F, GLU124F, GLU131E, GLU55E, GLU60E, GLU67E, GLU85F, GLU91F, GLU92F, GLU95F, GLY133E, GLY43E, GLY43F, GLY88F, ILE100E, ILE126F, ILE61E, ILE77E, ILE77F, ILE80E, ILE80F, ILE83F, ILE90F, LEU106F, LEU110F, LEU128E, LEU128F, LEU138E, LEU76E, LEU97E, LEU97F, LYS101E, LYS59E, LYS68E, LYS89F, MET98E, MET98F, MET99E, MET99F, PHE135E, PHE49E, PHE49F, PRO108F, PRO119F, PRO129E, PRO129F, PRO136E, PRO42E, PRO42F, PRO78E, PRO78F, SER104F, SER105F, SER44F, SER46E, SER46F, SER82F, THR102E, THR102F, THR111F, THR51F, THR81F, TRP140E, TRP86F, TYR120F, TYR137E, TYR40E, TYR84F, VAL107F, VAL114F, VAL122F, VAL125F, VAL130E, VAL130F, VAL141E, VAL144E, VAL45E, VAL45F, VAL50F, VAL65E, VAL66E, VAL74E, VAL96E, VAL96F