1XHM

the crystal structure of a biologically active peptide (sigk) bound to a g protein beta:gamma heterodimer

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 151
  • Norm. En. per Res.: -3.8924
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-72.9363	-41.4706	-473.345	-587.7519	151	34	29	20795	3	50	49
A-C	-27.8636	-15.2257	-142.481	-185.5704	57	10	3	5429	2	11	5

Interface residues

• A-B: ALA10B, ALA11A, ALA12B, ALA21A, ALA23B, ALA240A, ALA24A, ALA257A, ALA26A, ALA28A, ALA299A, ALA305A, ALA326A, ALA33B, ALA34B, ALA35B, ALA39B, ALA43B, ALA45B, ALA7B, ARG13B, ARG19A, ARG219A, ARG22A, ARG256A, ARG27B, ARG283A, ARG42A, ARG8A, ASN16A, ASN237A, ASN239A, ASN24B, ASN340A, ASN35A, ASN36A, ASP20A, ASP254A, ASP258A, ASP26B, ASP27A, ASP298A, ASP322A, ASP323A, ASP36B, ASP38A, ASP48B, ASP5A, CYS218A, CYS25A, CYS41B, GLN11B, GLN13A, GLN17A, GLN18B, GLN220A, GLN259A, GLN32A, GLN44A, GLN6A, GLN9A, GLU10A, GLU12A, GLU17B, GLU215A, GLU22B, GLU260A, GLU3A, GLU42B, GLU47B, GLY182A, GLY238A, GLY282A, GLY319A, GLY324A, GLY41A, HIS183A, HIS44B, ILE18A, ILE25B, ILE28B, ILE33A, ILE37A, ILE43A, ILE9B, LEU14A, LEU15B, LEU19B, LEU210A, LEU252A, LEU255A, LEU261A, LEU284A, LEU286A, LEU300A, LEU308A, LEU30A, LEU37B, LEU4A, LEU50B, LEU51B, LEU7A, LYS14B, LYS15A, LYS209A, LYS20B, LYS23A, LYS280A, LYS29B, LYS301A, LYS32B, LYS46B, MET217A, MET21B, MET262A, MET325A, MET38B, MET45A, PHE222A, PHE235A, PHE241A, PHE253A, PHE278A, PRO194A, PRO236A, PRO39A, PRO49B, SER279A, SER281A, SER2A, SER31A, SER31B, SER8B, THR181A, THR184A, THR221A, THR223A, THR29A, THR321A, THR34A, THR52B, TRP211A, TRP339A, TYR264A, TYR40B, VAL16B, VAL296A, VAL30B, VAL320A, VAL327A, VAL40A
• A-C: ALA203A, ALA5C, ALA60A, ARG314A, ASN119A, ASN230A, ASP118A, ASP163A, ASP186A, ASP228A, ASP246A, ASP290A, CYS204A, GLN75A, GLY10C, GLY115A, GLY116A, GLY144A, GLY162A, GLY185A, GLY244A, GLY272A, GLY3C, ILE229A, ILE273A, ILE2C, ILE58A, ILE8C, LEU117A, LEU146A, LEU9C, LYS4C, LYS57A, LYS7C, MET101A, MET188A, PHE6C, PRO12C, SER147A, SER1C, SER227A, SER245A, SER316A, SER74A, SER97A, SER98A, THR102A, THR143A, THR164A, THR274A, TRP332A, TRP99A, TYR11C, TYR145A, TYR59A, VAL100A, VAL187A