1XE0

the structure and function of xenopus no38-core, a histone binding chaperone in the nucleolus

• Total interactions analyzed: 45
• Total true interactions: 30
• Strongest Interaction:
  • Chains: F-J
  • Int. Res.: 106
  • Norm. En. per Res.: -3.4673
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-15.8458	-12.7212	-302.596	-331.1631	114	11	14	12246	0	10	11
A-C	0.0	0.0	-0.0159	-0.0159	5	0	0	6	0	0	0
A-D	0.0	0.0	-0.0158	-0.0158	5	0	0	7	0	0	0
A-E	-47.2133	-11.0695	-305.683	-363.9658	108	9	14	12235	0	9	13
A-F	-14.8905	13.922	-3.6298	-4.5982	20	3	0	842	0	8	5
A-G	0.0	-6.6879	-5.4191	-12.107	16	4	0	623	0	12	8
B-C	-13.8756	-13.6018	-282.306	-309.7835	106	10	12	11809	0	11	11
B-D	0.0	0.0	-0.0117	-0.0117	4	0	0	5	0	0	0
B-E	0.0	0.0	-0.0117	-0.0117	2	0	0	4	0	0	0
B-F	0.0	-4.6354	-3.3567	-7.9921	13	0	0	415	0	12	8
B-J	0.0	19.6387	-9.2576	10.381	18	0	0	621	0	8	6
C-D	-18.0331	-10.813	-285.245	-314.0911	104	7	11	11908	0	10	12
C-E	0.0	0.0	-0.0109	-0.0109	6	0	0	5	0	0	0
C-I	0.0	15.5351	-8.792	6.7432	18	0	0	685	0	8	5
C-J	0.0	-2.1437	-4.4107	-6.5543	14	0	0	389	0	12	8
D-E	-19.6846	-10.2593	-281.653	-311.597	106	14	13	11797	0	9	14
D-H	0.0	14.2672	-7.833	6.4342	18	0	0	661	0	8	5
D-I	0.0	-12.7801	-3.8751	-16.6552	18	4	0	683	0	12	8
E-G	0.0	16.3614	-7.7371	8.6243	18	0	0	604	0	8	4
E-H	0.0	-7.2303	-5.0759	-12.3061	16	4	0	643	0	12	8
F-G	-26.2967	-11.2248	-280.302	-317.8234	105	11	10	11745	0	10	11
F-H	0.0	0.0	-0.0128	-0.0128	6	0	0	5	0	0	0
F-I	0.0	0.0	-0.0289	-0.0289	7	0	0	8	0	0	0
F-J	-60.7944	-10.4527	-296.286	-367.5332	106	8	14	12135	0	10	12
G-H	-24.1883	-9.6056	-293.494	-327.2879	108	10	13	12101	0	10	13
G-I	0.0	0.0	-0.0117	-0.0117	4	0	0	4	0	0	0
G-J	0.0	0.0	-0.0098	-0.0098	4	0	0	3	0	0	0
H-I	-35.6129	-9.4403	-301.881	-346.9342	107	9	14	12286	0	9	13
H-J	0.0	0.0	-0.0096	-0.0096	4	0	0	3	0	0	0
I-J	-50.1749	-12.4759	-303.831	-366.4818	107	6	12	12095	0	10	12

Interface residues

• A-B: ALA120A, ALA120B, ALA53A, ALA55A, ALA64B, ALA77B, ALA79B, ARG13A, ARG47A, ARG47B, ASN17A, ASN40A, ASN68B, ASP37A, ASP38A, CYS22A, GLN116A, GLN16A, GLN43B, GLN86A, GLN86B, GLU23A, GLU36A, GLU39A, GLU41A, GLU41B, GLU58B, GLU63B, GLU65B, GLU70B, GLU95B, GLY107B, GLY115A, GLY14A, GLY21A, GLY52A, GLY66B, GLY71B, GLY92A, GLY92B, GLY93A, GLY93B, HIS117A, HIS42A, HIS42B, HIS60B, ILE101B, ILE67B, ILE74B, ILE76B, ILE96B, LEU102B, LEU118A, LEU118B, LEU19A, LEU44B, LEU46A, LEU46B, LEU51A, LEU59B, LEU78B, LEU81A, LEU81B, LEU91A, LEU91B, LYS105B, LYS34A, LYS72B, LYS75B, LYS82A, LYS82B, PHE18A, PHE20A, PHE33A, PHE94B, PRO110A, PRO83A, PRO87A, PRO87B, PRO98B, PRO99B, SER106B, SER114A, SER15A, SER45A, SER45B, SER50A, SER54A, SER80B, SER84A, SER84B, SER90A, SER90B, THR48A, THR73B, THR88A, THR88B, THR97B, TYR112A, TYR31A, TYR69B, VAL100B, VAL111A, VAL113A, VAL119A, VAL35A, VAL49A, VAL49B, VAL61B, VAL62B, VAL85A, VAL85B, VAL89A, VAL89B
• A-C: GLN86A, GLN86C, SER84A, VAL85A, VAL85C
• A-D: GLN86A, GLN86D, SER84D, VAL85A, VAL85D
• A-E: ALA53E, ALA55E, ALA64A, ALA77A, ALA79A, ARG47A, ARG47E, ASN17E, ASN40E, ASN68A, ASP37E, ASP57E, CYS22E, GLN116E, GLN16E, GLN43A, GLN86A, GLN86E, GLU23E, GLU36E, GLU41A, GLU58A, GLU63A, GLU65A, GLU70A, GLU95A, GLY107A, GLY115E, GLY21E, GLY52E, GLY66A, GLY71A, GLY92A, GLY92E, GLY93A, GLY93E, HIS117E, HIS42A, HIS42E, HIS60A, ILE101A, ILE67A, ILE74A, ILE76A, ILE96A, LEU102A, LEU118E, LEU19E, LEU44A, LEU46A, LEU46E, LEU51A, LEU51E, LEU59A, LEU78A, LEU81A, LEU81E, LEU91A, LEU91E, LYS105A, LYS34E, LYS72A, LYS75A, LYS82A, LYS82E, PHE18E, PHE20E, PHE33E, PHE94A, PRO110E, PRO83E, PRO87A, PRO87E, PRO98A, PRO99A, SER106A, SER114E, SER15E, SER45A, SER45E, SER50E, SER54E, SER80A, SER84A, SER84E, SER90A, SER90E, THR48E, THR73A, THR88A, THR88E, THR97A, TYR112E, TYR31E, TYR69A, VAL100A, VAL111E, VAL113E, VAL119E, VAL35E, VAL49A, VAL49E, VAL61A, VAL62A, VAL85A, VAL85E, VAL89A, VAL89E
• A-F: ALA53A, ALA53F, ALA55A, ALA55F, ASP57A, ASP57F, GLY52A, LYS56A, LYS56F, LYS82A, LYS82F, PRO110A, PRO83A, PRO83F, SER54A, SER54F, SER84A, SER84F, VAL85A, VAL85F
• A-G: ASP57A, ASP57G, GLU58A, GLU58G, GLY107A, LEU59A, LEU59G, LYS56G, LYS82A, LYS82G, PRO83G, SER106A, SER84A, SER84G, VAL85A, VAL85G
• B-C: ALA53B, ALA55B, ALA64C, ALA77C, ALA79C, ARG47B, ARG47C, ASN17B, ASN40B, ASN68C, ASP38B, ASP57B, CYS22B, GLN116B, GLN16B, GLN43C, GLN86B, GLN86C, GLU23B, GLU36B, GLU41B, GLU63C, GLU65C, GLU70C, GLU95C, GLY107C, GLY115B, GLY21B, GLY52B, GLY66C, GLY71C, GLY92B, GLY92C, GLY93B, GLY93C, HIS117B, HIS42B, HIS60C, ILE101C, ILE67C, ILE74C, ILE76C, ILE96C, LEU102C, LEU118B, LEU19B, LEU44C, LEU46B, LEU46C, LEU51B, LEU51C, LEU59C, LEU78C, LEU81B, LEU81C, LEU91B, LEU91C, LYS105C, LYS34B, LYS72C, LYS75C, LYS82B, LYS82C, PHE18B, PHE20B, PHE33B, PHE94C, PRO110B, PRO83B, PRO87B, PRO87C, PRO98C, PRO99C, SER106C, SER114B, SER15B, SER45B, SER45C, SER50B, SER54B, SER80C, SER84B, SER84C, SER90B, SER90C, THR48B, THR73C, THR88B, THR88C, THR97C, TYR112B, TYR31B, TYR69C, VAL100C, VAL111B, VAL113B, VAL119B, VAL35B, VAL49B, VAL49C, VAL61C, VAL62C, VAL85B, VAL85C, VAL89B, VAL89C
• B-D: GLN86B, GLN86D, VAL85B, VAL85D
• B-E: VAL85B, VAL85E
• B-F: ASP57B, ASP57F, GLU58B, GLU58F, LEU59B, LEU59F, LYS56F, LYS82B, LYS82F, SER84B, SER84F, VAL85B, VAL85F
• B-J: ALA53B, ALA53J, ALA55B, ALA55J, ASP57B, ASP57J, LYS56B, LYS56J, LYS82B, LYS82J, PRO83B, PRO83J, SER54B, SER54J, SER84B, SER84J, VAL85B, VAL85J
• C-D: ALA120C, ALA53C, ALA55C, ALA64D, ALA77D, ALA79D, ARG47C, ARG47D, ASN17C, ASN68D, CYS22C, GLN116C, GLN16C, GLN43D, GLN86C, GLN86D, GLU23C, GLU36C, GLU58D, GLU63D, GLU65D, GLU70D, GLU95D, GLY107D, GLY115C, GLY21C, GLY52C, GLY66D, GLY71D, GLY92C, GLY92D, GLY93C, GLY93D, HIS117C, HIS42C, HIS60D, ILE101D, ILE67D, ILE74D, ILE76D, ILE96D, LEU102D, LEU118C, LEU19C, LEU44C, LEU44D, LEU46C, LEU46D, LEU51C, LEU59D, LEU78D, LEU81C, LEU81D, LEU91C, LEU91D, LYS105D, LYS34C, LYS72D, LYS75D, LYS82C, LYS82D, PHE18C, PHE20C, PHE33C, PHE94D, PRO110C, PRO83C, PRO87C, PRO87D, PRO98D, PRO99D, SER106D, SER114C, SER45C, SER45D, SER50C, SER54C, SER80D, SER84C, SER84D, SER90C, SER90D, THR48C, THR48D, THR73D, THR88C, THR88D, THR97D, TYR112C, TYR31C, TYR69D, VAL100D, VAL111C, VAL113C, VAL119C, VAL35C, VAL49C, VAL49D, VAL61D, VAL62D, VAL85C, VAL85D, VAL89C, VAL89D
• C-E: GLN86E, GLY92C, GLY92E, PRO87C, VAL85C, VAL85E
• C-I: ALA53C, ALA53I, ALA55C, ALA55I, ASP57C, ASP57I, LYS56C, LYS56I, LYS82C, LYS82I, PRO83C, PRO83I, SER54C, SER54I, SER84C, SER84I, VAL85C, VAL85I
• C-J: ASP57C, ASP57J, GLU58C, GLU58J, LEU59C, LEU59J, LYS56C, LYS82C, LYS82J, SER106J, SER84C, SER84J, VAL85C, VAL85J
• D-E: ALA53D, ALA55D, ALA64E, ALA77E, ALA79E, ARG47D, ARG47E, ASN17D, ASN40D, ASN68E, ASP38D, CYS22D, GLN116D, GLN16D, GLN43E, GLN86D, GLN86E, GLU23D, GLU36D, GLU58E, GLU63E, GLU65E, GLU70E, GLU95E, GLY107E, GLY115D, GLY21D, GLY52D, GLY66E, GLY71E, GLY92D, GLY92E, GLY93D, GLY93E, HIS117D, HIS42D, HIS60E, ILE101E, ILE67E, ILE74E, ILE76E, ILE96E, LEU102E, LEU118D, LEU19D, LEU44D, LEU44E, LEU46D, LEU46E, LEU51D, LEU59E, LEU78E, LEU81D, LEU81E, LEU91D, LEU91E, LYS105E, LYS25D, LYS34D, LYS72E, LYS75E, LYS82D, LYS82E, PHE18D, PHE20D, PHE33D, PHE94E, PRO110D, PRO83D, PRO87D, PRO87E, PRO98E, PRO99E, SER106E, SER114D, SER15D, SER45D, SER45E, SER50D, SER54D, SER80E, SER84D, SER84E, SER90D, SER90E, THR48D, THR73E, THR88D, THR88E, THR97E, TYR112D, TYR31D, TYR69E, VAL100E, VAL111D, VAL113D, VAL119D, VAL35D, VAL49D, VAL49E, VAL61E, VAL62E, VAL85D, VAL85E, VAL89D, VAL89E
• D-H: ALA53D, ALA53H, ALA55D, ALA55H, ASP57D, ASP57H, LYS56D, LYS56H, LYS82D, LYS82H, PRO83D, PRO83H, SER54D, SER54H, SER84D, SER84H, VAL85D, VAL85H
• D-I: ASP57D, ASP57I, GLU58D, GLU58I, GLY107I, LEU59D, LEU59I, LYS56D, LYS56I, LYS82D, LYS82I, PRO83D, PRO83I, SER106I, SER84D, SER84I, VAL85D, VAL85I
• E-G: ALA53E, ALA53G, ALA55E, ALA55G, ASP57E, ASP57G, LYS56E, LYS56G, LYS82E, LYS82G, PRO83E, PRO83G, SER54E, SER54G, SER84E, SER84G, VAL85E, VAL85G
• E-H: ASP57E, ASP57H, GLU58E, GLU58H, LEU59E, LEU59H, LYS56E, LYS56H, LYS82E, LYS82H, PRO83E, SER106E, SER84E, SER84H, VAL85E, VAL85H
• F-G: ALA53F, ALA55F, ALA64G, ALA77G, ALA79G, ARG47F, ARG47G, ASN17F, ASN40F, ASN68G, ASP38F, CYS22F, GLN116F, GLN16F, GLN43G, GLN86F, GLN86G, GLU23F, GLU36F, GLU41G, GLU58G, GLU63G, GLU65G, GLU70G, GLU95G, GLY107G, GLY115F, GLY14F, GLY21F, GLY52F, GLY66G, GLY71G, GLY92F, GLY92G, GLY93F, GLY93G, HIS117F, HIS42F, HIS60G, ILE101G, ILE67G, ILE74G, ILE76G, ILE96G, LEU102G, LEU118F, LEU19F, LEU44G, LEU46F, LEU46G, LEU51F, LEU59G, LEU78G, LEU81F, LEU81G, LEU91F, LEU91G, LYS105G, LYS34F, LYS72G, LYS75G, LYS82F, LYS82G, PHE18F, PHE20F, PHE33F, PHE94G, PRO110F, PRO83F, PRO87F, PRO87G, PRO99G, SER106G, SER114F, SER15F, SER45F, SER45G, SER50F, SER54F, SER80G, SER84F, SER84G, SER90F, SER90G, THR48F, THR73G, THR88F, THR88G, THR97G, TYR112F, TYR31F, TYR69G, VAL100G, VAL111F, VAL113F, VAL119F, VAL35F, VAL49F, VAL49G, VAL61G, VAL62G, VAL85F, VAL85G, VAL89F, VAL89G
• F-H: GLN86F, GLN86H, SER90F, SER90H, VAL85F, VAL85H
• F-I: GLN86F, GLN86I, SER84I, SER90F, SER90I, VAL85F, VAL85I
• F-J: ALA53J, ALA55J, ALA64F, ALA77F, ALA79F, ARG47F, ARG47J, ASN17J, ASN40J, ASN68F, CYS22J, GLN116J, GLN16J, GLN43F, GLN86F, GLN86J, GLU23J, GLU36J, GLU39J, GLU41F, GLU58F, GLU63F, GLU65F, GLU70F, GLU95F, GLY107F, GLY115J, GLY21J, GLY52J, GLY66F, GLY71F, GLY92F, GLY92J, GLY93F, GLY93J, HIS117J, HIS42F, HIS42J, HIS60F, ILE101F, ILE67F, ILE74F, ILE76F, ILE96F, LEU102F, LEU118J, LEU19J, LEU44F, LEU46F, LEU46J, LEU51J, LEU59F, LEU78F, LEU81F, LEU81J, LEU91F, LEU91J, LYS105F, LYS34J, LYS72F, LYS75F, LYS82F, LYS82J, PHE18J, PHE20J, PHE33J, PHE94F, PRO110J, PRO83J, PRO87F, PRO87J, PRO98F, PRO99F, SER106F, SER114J, SER15J, SER45F, SER45J, SER50J, SER54J, SER80F, SER84F, SER84J, SER90F, SER90J, THR48J, THR73F, THR88F, THR88J, THR97F, TYR112J, TYR31J, TYR69F, VAL100F, VAL111J, VAL113J, VAL119J, VAL35J, VAL49F, VAL49J, VAL61F, VAL62F, VAL85F, VAL85J, VAL89F, VAL89J
• G-H: ALA53G, ALA55G, ALA64H, ALA77H, ALA79H, ARG47G, ARG47H, ASN17G, ASN40G, ASN68H, ASP37G, ASP38G, CYS22G, GLN116G, GLN16G, GLN43H, GLN86G, GLN86H, GLU23G, GLU36G, GLU41G, GLU41H, GLU58H, GLU63H, GLU65H, GLU70H, GLU95H, GLY107H, GLY115G, GLY21G, GLY52G, GLY66H, GLY71H, GLY92G, GLY92H, GLY93G, GLY93H, HIS117G, HIS42G, HIS60H, ILE101H, ILE67H, ILE74H, ILE76H, ILE96H, LEU102H, LEU118G, LEU19G, LEU44G, LEU44H, LEU46G, LEU46H, LEU51G, LEU59H, LEU78H, LEU81G, LEU81H, LEU91G, LEU91H, LYS105H, LYS34G, LYS72H, LYS75H, LYS82G, LYS82H, PHE18G, PHE20G, PHE33G, PHE94H, PRO110G, PRO83G, PRO87G, PRO87H, PRO98H, PRO99H, SER106H, SER114G, SER15G, SER45G, SER45H, SER50G, SER54G, SER80H, SER84G, SER84H, SER90G, SER90H, THR48G, THR73H, THR88G, THR88H, THR97H, TYR112G, TYR31G, TYR69H, VAL100H, VAL111G, VAL113G, VAL119G, VAL35G, VAL49G, VAL49H, VAL61H, VAL62H, VAL85G, VAL85H, VAL89G, VAL89H
• G-I: GLN86G, GLN86I, VAL85G, VAL85I
• G-J: GLN86G, GLN86J, VAL85G, VAL85J
• H-I: ALA53H, ALA55H, ALA64I, ALA77I, ALA79I, ARG47H, ARG47I, ASN17H, ASN40H, ASN68I, ASP37H, ASP38H, ASP57H, CYS22H, GLN116H, GLN16H, GLN43I, GLN86H, GLN86I, GLU23H, GLU41I, GLU58I, GLU63I, GLU65I, GLU70I, GLU95I, GLY107I, GLY115H, GLY21H, GLY52H, GLY66I, GLY71I, GLY92H, GLY92I, GLY93H, GLY93I, HIS117H, HIS42H, HIS42I, HIS60I, ILE101I, ILE67I, ILE74I, ILE76I, ILE96I, LEU102I, LEU118H, LEU19H, LEU44I, LEU46H, LEU46I, LEU51H, LEU59I, LEU78I, LEU81H, LEU81I, LEU91H, LEU91I, LYS105I, LYS34H, LYS72I, LYS75I, LYS82H, LYS82I, PHE18H, PHE20H, PHE33H, PHE94I, PRO110H, PRO83H, PRO87H, PRO87I, PRO98I, PRO99I, SER106I, SER114H, SER15H, SER45H, SER45I, SER50H, SER54H, SER80I, SER84H, SER84I, SER90H, SER90I, THR48H, THR73I, THR88H, THR88I, THR97I, TYR112H, TYR31H, TYR69I, VAL100I, VAL111H, VAL113H, VAL119H, VAL35H, VAL49H, VAL49I, VAL61I, VAL62I, VAL85H, VAL85I, VAL89H, VAL89I
• H-J: GLN86H, GLN86J, VAL85H, VAL85J
• I-J: ALA53I, ALA55I, ALA64J, ALA77J, ALA79J, ARG47I, ARG47J, ASN17I, ASN68J, ASP38I, CYS22I, GLN116I, GLN16I, GLN43J, GLN86I, GLN86J, GLU23I, GLU36I, GLU41J, GLU58J, GLU63J, GLU65J, GLU70J, GLU95J, GLY107J, GLY115I, GLY21I, GLY52I, GLY66J, GLY71J, GLY92I, GLY92J, GLY93I, GLY93J, HIS117I, HIS42I, HIS42J, HIS60J, ILE101J, ILE67J, ILE74J, ILE76J, ILE96J, LEU102J, LEU118I, LEU19I, LEU44I, LEU44J, LEU46I, LEU46J, LEU51I, LEU59J, LEU78J, LEU81I, LEU81J, LEU91I, LEU91J, LYS105J, LYS34I, LYS72J, LYS75J, LYS82I, LYS82J, PHE18I, PHE20I, PHE33I, PHE94J, PRO110I, PRO83I, PRO87I, PRO87J, PRO98J, PRO99J, SER106J, SER114I, SER15I, SER45I, SER45J, SER50I, SER54I, SER80J, SER84I, SER84J, SER90I, SER90J, THR48I, THR48J, THR73J, THR88I, THR88J, THR97J, TYR112I, TYR31I, TYR69J, VAL100J, VAL111I, VAL113I, VAL119I, VAL35I, VAL49I, VAL49J, VAL61J, VAL62J, VAL85I, VAL85J, VAL89I, VAL89J