1XB4

crystal structure of subunit vps25 of the endosomal trafficking complex escrt-ii

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 75
  • Norm. En. per Res.: -2.6067
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-147.958	-147.958	71	6	1	6827	0	2	1
A-C	-44.3798	-53.4406	-97.6788	-195.4992	75	12	0	4904	4	15	16
B-C	-27.7173	-6.9519	-78.9344	-113.6036	65	14	0	3759	0	28	25
C-D	-4.3987	0.0	-156.321	-160.7197	67	11	1	7048	0	2	3

Interface residues

• A-B: ARG16A, ARG16B, ARG23A, ARG23B, ARG24A, ARG24B, ARG83A, ARG83B, ASN19A, ASN19B, ASN78A, ASN78B, ASP32A, ASP32B, ASP80A, ASP80B, GLN17A, GLN17B, GLN25A, GLN25B, GLN26A, GLN26B, GLN36A, GLN82A, ILE27A, ILE27B, ILE31A, ILE31B, ILE33A, ILE33B, ILE81A, ILE81B, LEU13A, LEU13B, LEU21A, LEU21B, LEU4B, LYS102B, MET1B, PHE10A, PHE10B, PHE89A, PHE89B, PRO11A, PRO11B, PRO12A, PRO12B, PRO18A, PRO18B, PRO5A, PRO5B, PRO6A, PRO6B, SER28A, SER28B, SER9A, SER9B, THR15A, THR15B, THR22A, THR22B, THR29A, THR29B, TRP30A, TRP30B, TYR14A, TYR14B, TYR8A, TYR8B, VAL7A, VAL7B
• A-C: ALA3A, ARG112C, ARG167A, ARG16C, ARG83A, ARG83C, ASN115C, ASN162A, ASN54A, ASN74A, ASN77A, ASN77C, ASN78A, ASN78C, ASP107C, ASP158A, ASP49C, ASP55A, ASP80A, ASP91C, GLN108C, GLN82A, GLN82C, GLN87C, GLU159A, GLU79A, GLU79C, GLU92C, GLY50C, HIS166A, ILE43A, ILE53A, ILE53C, ILE81A, ILE81C, ILE90C, LEU4A, LEU75A, LYS39A, LYS41A, LYS42A, LYS73A, MET1A, PHE10A, PHE76A, PHE89C, PRO11C, PRO5A, PRO6A, SER113C, SER114C, SER2A, SER47C, SER84C, SER86C, SER9A, THR116C, THR117C, THR118C, THR119C, THR15C, THR160A, THR40A, THR51C, TRP163A, TRP94C, TYR14A, TYR14C, TYR37A, TYR8A, VAL48C, VAL52A, VAL7A, VAL85C, VAL88C
• B-C: ARG111B, ARG111C, ARG112B, ARG112C, ARG120C, ARG167C, ARG183B, ARG185B, ARG24B, ASN115B, ASN115C, ASN193C, ASN54C, ASN56C, ASP107C, ASP129B, ASP182B, ASP191C, ASP194C, ASP32B, ASP55C, ASP91B, CYS103B, GLN108C, GLN25B, GLN96B, GLU100B, GLU192C, GLU92B, GLY101B, GLY110C, ILE106C, ILE197C, ILE31B, ILE93B, LEU136B, LEU21B, LYS102B, LYS190C, LYS195C, LYS99B, MET97B, PRO105B, SER109C, SER113B, SER113C, SER114B, SER133B, SER171C, SER20B, SER28B, SER95B, THR116B, THR116C, THR117C, THR118B, THR119C, THR22B, THR29B, THR98B, TRP94B, TYR121B, TYR152C, TYR175C, VAL196C
• C-D: ARG16C, ARG16D, ARG23C, ARG23D, ARG24C, ARG24D, ARG83C, ARG83D, ASN19C, ASN78D, ASP32C, ASP32D, ASP80D, GLN17C, GLN17D, GLN25C, GLN25D, GLN26C, GLN26D, GLN36C, GLN36D, GLN82D, ILE27C, ILE27D, ILE31C, ILE31D, ILE33C, ILE33D, ILE81C, ILE81D, LEU13C, LEU13D, LEU21C, LEU4D, LYS102C, PHE10C, PHE10D, PHE89C, PHE89D, PRO11C, PRO11D, PRO12C, PRO12D, PRO18C, PRO18D, PRO5C, PRO5D, PRO6C, PRO6D, SER28C, SER28D, SER9C, SER9D, THR15C, THR15D, THR22C, THR22D, THR29C, THR29D, TRP30C, TRP30D, TYR14C, TYR14D, TYR8C, TYR8D, VAL7C, VAL7D